Major depression disorder is a common illness that severely limits psychosocial functioning, affects outcomes of other diseases, and diminishes the quality of life. High-salt diet (HSD) has long been closely associated with the occurrence and development of depression, but whether or how HSD causes depression remains unclear. In this study, HSD induces depression-like behavior in… Continue reading High- #salt #diet drives depression-like behavior in mice by inducing IL-17A production
Tag: Salt
#Sodium Intake and #Atopic Dermatitis
Question Is a higher level of sodium intake associated with risk of atopic dermatitis (AD)?Findings In this cross-sectional study of 215 832 adults from the UK Biobank cohort, a 1-g higher estimated 24-hour urine sodium excretion was associated with an 11% higher odds of AD diagnosis, 16% higher odds of active AD, and 11% higher odds of increasing… Continue reading #Sodium Intake and #Atopic Dermatitis
Self-Reported Frequency of Adding #Salt to Food and Risk of Incident Chronic #Kidney Disease
Importance The self-reported frequency of adding salt to foods could reflect a person’s long-term salt taste preference, and salt intake has been associated with increased risk of cardiovascular diseases (CVD). Whether self-reported adding of salt to foods is associated with increased risk of chronic kidney disease (CKD) remains unknown.Objective To prospectively examine the association of self-reported frequency… Continue reading Self-Reported Frequency of Adding #Salt to Food and Risk of Incident Chronic #Kidney Disease
Effect of Dietary #Sodium on Blood #PressureA Crossover Trial
Dietary sodium recommendations are debated partly due to variable blood pressure (BP) response to sodium intake. Furthermore, the BP effect of dietary sodium among individuals taking antihypertensive medications is understudied.Objectives To examine the distribution of within-individual BP response to dietary sodium, the difference in BP between individuals allocated to consume a high- or low-sodium diet first,… Continue reading Effect of Dietary #Sodium on Blood #PressureA Crossover Trial
Dietary #Sodium Intake and Risk of Incident Type 2 #Diabetes
ObjectiveTo fill the knowledge gap of the relation between long-term dietary sodium intake and type 2 diabetes (T2D), we evaluate the association between the frequency of adding salt to foods, a surrogate marker for evaluating the long-term sodium intake, and incident T2D risk.MethodsA total of 402,982 participants from UK Biobank (March 13, 2006 – October… Continue reading Dietary #Sodium Intake and Risk of Incident Type 2 #Diabetes
Salt Sensitivity of Blood Pressure in Women
Several clinical and large population studies indicate that women are more salt-sensitive than men, yet the precise mechanisms by which the sexually dimorphic onset manifests remains incompletely understood. Here, we evaluate recent epidemiological data and highlight current knowledge from studies investigating sex-specific mechanisms of salt-sensitive blood pressure (SSBP). Emerging evidence indicates that women of all… Continue reading Salt Sensitivity of Blood Pressure in Women
Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis
Objectives The Salt Substitute and Stroke Study (SSaSS) recently reported blood pressure-mediated benefits of a potassium-enriched salt substitute on cardiovascular outcomes and death. This study assessed the effects of salt substitutes on a breadth of outcomes to quantify the consistency of the findings and understand the likely generalisability of the SSaSS results.Methods We searched PubMed,… Continue reading Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis
The global epidemiology of #hypertension
Hypertension is the leading cause of cardiovascular disease and premature death worldwide. Owing to the widespread use of antihypertensive medications, global mean blood pressure (BP) has remained constant or has decreased slightly over the past four decades. By contrast, the prevalence of hypertension has increased, especially in low- and middle-income countries (LMICs). Estimates suggest that… Continue reading The global epidemiology of #hypertension
Greater T Regulatory Cells in Females Attenuate DOCA-Salt–Induced Increases in Blood Pressure Versus Males
Hypertension is the most common risk factor for cardiovascular disease, causing over 18 million deaths a year. Although the mechanisms controlling blood pressure (BP) in either sex remain largely unknown, T cells play a critical role in the development of hypertension. Further evidence supports a role for the immune system in contributing to sex differences… Continue reading Greater T Regulatory Cells in Females Attenuate DOCA-Salt–Induced Increases in Blood Pressure Versus Males
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