Effect of #Metformin on the Risk of Post- #coronavirus Disease 2019 Condition Among Individuals With #Overweight or #Obese: A Population-based Retrospective Cohort Study

BackgroundA subgroup analysis of the COVID-OUT trial's long-term outcome found that starting metformin within 3 days of coronavirus disease 2019 (COVID-19) diagnosis reduced post–COVID-19 condition (PCC) incidence by 63% in overweight or obese individuals. However, its generalizability remains uncertain.ObjectivesTo evaluate the effectiveness of metformin in preventing PCC in adults with overweight or obesity who had… Continue reading Effect of #Metformin on the Risk of Post- #coronavirus Disease 2019 Condition Among Individuals With #Overweight or #Obese: A Population-based Retrospective Cohort Study

3-month program of time-restricted #eating at any time of the day supports long-term #weight loss in adults with overweight or obesity

Three months of time-restricted eating (TRE), irrespective of whether it is earlier or later in the day, may be a promising strategy for sustaining long-term weight loss in adults with overweight or obesity, according to preliminary results of a randomised controlled trial being presented at this year’s European Congress on Obesity (ECO) in Malaga, Spain… Continue reading 3-month program of time-restricted #eating at any time of the day supports long-term #weight loss in adults with overweight or obesity

Can #carbonated water support weight loss?

Background Carbonated water has been reported to induce satiety, gastric motility and lower serum glucose concentrations, but the mechanisms remain unclear.Methods This report explores the physiological effects of carbonated water, referencing a study published in 2004 on the mechanisms of hypoglycaemia induced by haemodialysis.Results Upon consumption of carbonated water, carbon dioxide (CO2) is absorbed into… Continue reading Can #carbonated water support weight loss?

Blood #Pressure Decreases in #Overweight Elderly Individuals on Vitamin #D: A Randomized Trial

AbstractContextEvidence for a beneficial role of vitamin D on blood pressure (BP) outcomes is inconclusive.ObjectiveThis work aimed to investigate the effect of 2 doses of cholecalciferol (vitamin D3) supplementation coadministered with calcium on systolic blood pressure (SBP) and diastolic blood pressure (DBP).MethodsExploratory analyses were conducted from a 1-year, multicenter, double-blind, randomized controlled trial (RCT). Total… Continue reading Blood #Pressure Decreases in #Overweight Elderly Individuals on Vitamin #D: A Randomized Trial

#Overweight in #Adolescence and Young Adulthood in Association With Adult #Cerebrovascular Disease: The NFBC1966 Study

BACKGROUND:Risk factors for cerebrovascular disease in adulthood are well known. However, research on individuals’ risk factors throughout their life span has been limited. This prospective cohort study aims to determine the effect of body mass index (BMI) and its changes in adolescence and young adulthood on early onset cerebrovascular disease.METHODS:This study includes 10 491 people (5185… Continue reading #Overweight in #Adolescence and Young Adulthood in Association With Adult #Cerebrovascular Disease: The NFBC1966 Study

Apple cider # for weight management in Lebanese adolescents and young adults with #overweight and obesity: a randomised, double-blind, placebo-controlled study

Background and aims Obesity and overweight have become significant health concerns worldwide, leading to an increased interest in finding natural remedies for weight reduction. One such remedy that has gained popularity is apple cider vinegar (ACV).Objective To investigate the effects of ACV consumption on weight, blood glucose, triglyceride and cholesterol levels in a sample of the Lebanese… Continue reading Apple cider # for weight management in Lebanese adolescents and young adults with #overweight and obesity: a randomised, double-blind, placebo-controlled study

Consumption of 100% Fruit #Juice and Body #Weight in Children and AdultsA Systematic Review and Meta-Analysis

Importance  Concerns have been raised that frequent consumption of 100% fruit juice may promote weight gain. Current evidence on fruit juice and weight gain has yielded mixed findings from both observational studies and clinical trials.Objective  To synthesize the available evidence on 100% fruit juice consumption and body weight in children and adults.Data Sources  MEDLINE, Embase, and Cochrane databases… Continue reading Consumption of 100% Fruit #Juice and Body #Weight in Children and AdultsA Systematic Review and Meta-Analysis

Mechanisms of #weight loss-induced remission in people with #prediabetes: a post-hoc analysis of the randomised, controlled, multicentre Prediabetes Lifestyle Intervention Study (PLIS)

Background Remission of type 2 diabetes can occur as a result of weight loss and is characterised by liver fat and pancreas fat reduction and recovered insulin secretion. In this analysis, we aimed to investigate the mechanisms of weight loss- induced remission in people with prediabetes.MethodsIn this prespecified post-hoc analysis, weight loss-induced resolution of prediabetes… Continue reading Mechanisms of #weight loss-induced remission in people with #prediabetes: a post-hoc analysis of the randomised, controlled, multicentre Prediabetes Lifestyle Intervention Study (PLIS)

#Almonds vs. #carbohydrate snacks in an energy-restricted diet: Weight and cardiometabolic outcomes from a randomized trial

ObjectiveThis study evaluated weight and cardiometabolic outcomes after a 3-month energy-restricted diet (−30%) containing almonds (almond-enriched diet [AED]) or containing carbohydrate-rich snacks (nut-free control diet [NFD]) (Phase 1), followed by 6 months of weight maintenance (Phase 2).MethodsParticipants (25–65 years old) with overweight or obesity (BMI 27.5–34.9 kg/m2) were randomly allocated to AED (n = 68) or NFD (n = 72).ResultsBoth groups lost weight… Continue reading #Almonds vs. #carbohydrate snacks in an energy-restricted diet: Weight and cardiometabolic outcomes from a randomized trial