The Mediterranean Diet (MD) is plant-based and consists of multiple daily portions of vegetables, fruit, cereals, and olive oil. Although there are challenges with isolating the MD from the typical Mediterranean lifestyle and culture (including prolonged ‘social’ meals and siestas), much evidence supports the health benefits of the MD that include improved longevity, reduced metabolic… Continue reading The Effects of the #Mediterranean Diet on #Health and Gut #Microbiota
Tag: gut-microbiota
Controlled colonization of the human #gut with a genetically engineered microbial therapeutic
Editor’s summaryThe gut #microbiota has long been an aspirational target for clinical delivery of therapeutics. Successful therapy by this route depends on ensuring engraftment of the therapeutic organisms and their clearance after treatment. Whitaker et al. have engineered a strain of Bacteroides vulgatus, which is commonly found in the gut of healthy humans, with two… Continue reading Controlled colonization of the human #gut with a genetically engineered microbial therapeutic
Intestinal #Microbiota Contributes to the Development of #Cardiovascular Inflammation and Vasculitis in Mice
Alterations in the intestinal microbiota contribute to the pathogenesis of various cardiovascular disorders, but how they affect the development of Kawasaki disease (KD) an acute pediatric vasculitis, remains unclear.METHODS:We used the Lactobacillus casei cell wall extract (LCWE) murine model of KD vasculitis to assess the contribution of the intestinal microbiota to the development of vascular… Continue reading Intestinal #Microbiota Contributes to the Development of #Cardiovascular Inflammation and Vasculitis in Mice
Gut #microbiota markers in early #childhood are linked to #farm living, pets in household and allergy
BackgroundChildren growing up on farms or with pets have a lower risk of developing allergy, which may be linked to their gut microbiota development during infancy MethodsChildren from the FARMFLORA birth cohort (N = 65), of whom 28 (43%) lived on a dairy farm and 40 (62%) had pets, provided fecal samples at intervals from… Continue reading Gut #microbiota markers in early #childhood are linked to #farm living, pets in household and allergy
The central role of the gut #microbiota in the pathophysiology and management of type 2 #diabetes
The inhabitants of our intestines, collectively called the gut microbiome, comprise fungi, viruses, and bacterial strains. These microorganisms are involved in the fermentation of dietary compounds and the regulation of our adaptive and innate immune systems. Less known is the reciprocal interaction between the gut microbiota and type 2 diabetes mellitus (T2DM), as well as… Continue reading The central role of the gut #microbiota in the pathophysiology and management of type 2 #diabetes
Impact of Plant-Based Dietary #Fibers on Metabolic Homeostasis in High-#Fat Diet Mice via Alterations in the Gut #Microbiota and Metabolites
BackgroundThe gut microbiota contributes to metabolic disease, and diet shapes the gut microbiota, emphasizing the need to better understand how diet impacts metabolic disease via gut microbiota alterations. Fiber intake is linked with improvements in metabolic homeostasis in rodents and humans, which is associated with changes in the gut microbiota. However, dietary fiber is extremely… Continue reading Impact of Plant-Based Dietary #Fibers on Metabolic Homeostasis in High-#Fat Diet Mice via Alterations in the Gut #Microbiota and Metabolites
Multikingdom and functional gut #microbiota markers for #autism spectrum disorder
Associations between the gut microbiome and autism spectrum disorder (ASD) have been investigated although most studies have focused on the bacterial component of the microbiome. Whether gut archaea, fungi and viruses, or function of the gut microbiome, is altered in ASD is unclear. Here we performed metagenomic sequencing on faecal samples from 1,627 children (aged… Continue reading Multikingdom and functional gut #microbiota markers for #autism spectrum disorder
#Lactobacillus from the Altered Schaedler Flora maintain IFNγ homeostasis to promote #behavioral stress resilience
The gut microbiome consists of trillions of bacteria, fungi, and viruses that inhabit the digestive tract. These communities are sensitive to disruption from environmental exposures ranging from diet changes to illness. Disruption of the community of lactic acid producing bacteria, Lactobaccillacea, has been well documented in mood disorders and stress exposure. In fact, oral supplement with many Lactobacillus species… Continue reading #Lactobacillus from the Altered Schaedler Flora maintain IFNγ homeostasis to promote #behavioral stress resilience
#Prebiotic #diet changes neural correlates of #food decision-making in #overweight adults: a randomised controlled within-subject cross-over trial
Objective Animal studies suggest that prebiotic, plant-derived nutrients could improve homoeostatic and hedonic brain functions through improvements in microbiome–gut–brain communication. However, little is known if these results are applicable to humans. Therefore, we tested the effects of high-dosed prebiotic fibre on reward-related food decision-making in a randomised controlled within-subject cross-over study and assayed potential microbial and… Continue reading #Prebiotic #diet changes neural correlates of #food decision-making in #overweight adults: a randomised controlled within-subject cross-over trial
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