Phthalates and Incident Diabetes in Midlife Women: The Study of Women’s Health Across the Nation (SWAN)

ContextPhthalates are hypothesized to contribute to diabetes, but longitudinal evidence in humans is limited.ObjectiveWe examined whether phthalate exposure was associated with a higher incidence of diabetes in a racially/ethnically diverse cohort of midlife women.MethodsIn the Study of Women's Health Across the Nation Multipollutant Study, we followed 1308 women without diabetes in 1999-2000 for 6 years.… Continue reading Phthalates and Incident Diabetes in Midlife Women: The Study of Women’s Health Across the Nation (SWAN)

Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes

The role of vitamin D in people who are at risk for type 2 diabetes remains unclear.Purpose:To evaluate whether administration of vitamin D decreases risk for diabetes among people with prediabetes.Data Sources:PubMed, Embase, and ClinicalTrials.gov from database inception through 9 December 2022.Study Selection:Eligible trials that were specifically designed and conducted to test the effects of… Continue reading Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes

Dietary exposure to nitrites and nitrates in association with type 2 diabetes risk: Results from the NutriNet-Santé population-based cohort study

Nitrites and nitrates occur naturally in water and soil and are commonly ingested from drinking water and dietary sources. They are also used as food additives, mainly in processed meats, to increase shelf life and to avoid bacterial growth. Experimental studies suggested both benefits and harmful effects of nitrites and nitrates exposure on type 2… Continue reading Dietary exposure to nitrites and nitrates in association with type 2 diabetes risk: Results from the NutriNet-Santé population-based cohort study

Proton Pump Inhibitor Use and Risks of Cardiovascular Disease and Mortality in Patients With Type 2 Diabetes 

Proton pump inhibitors (PPIs) are widely used drugs for gastric acid–related diseases and may affect the gut microbiome.ObjectiveWe aimed to evaluate the associations of PPI use with risks of cardiovascular disease (CVD) and all-cause mortality in patients with type 2 diabetes (T2D).MethodsWe analyzed the associations of PPI use with risks of coronary artery disease (CAD),… Continue reading Proton Pump Inhibitor Use and Risks of Cardiovascular Disease and Mortality in Patients With Type 2 Diabetes 

Vegetable, But Not Potato, Intake is Associated With a Lower Risk of Type 2 Diabetes in the Danish Diet, Cancer and Health Cohort

To examine the relationship between intake of vegetables/potatoes and incident type 2 diabetes (T2D) and explore whether the relationship between vegetable intake and incident T2D is mediated by baseline BMI.RESEARCH DESIGN AND METHODSCross-sectional associations between exposure (baseline intake of total vegetables, vegetable subgroups, and potatoes) and baseline BMI were assessed by multivariable-adjusted linear regression models.… Continue reading Vegetable, But Not Potato, Intake is Associated With a Lower Risk of Type 2 Diabetes in the Danish Diet, Cancer and Health Cohort

Low-Energy Dense Potato- and Bean-Based Diets Reduce Body Weight and Insulin Resistance: A Randomized, Feeding, Equivalence Trial

AbstractWe evaluated the effect of diets low in energy density (1 kcal/g) and high in either potatoes (Potato) or pulses (Bean) on blood glucose control in participants with insulin resistance. We hypothesized that the Potato and Bean diets would have equivalent effects. This was an 8-week randomized, parallel design, controlled feeding study comparing Potato and… Continue reading Low-Energy Dense Potato- and Bean-Based Diets Reduce Body Weight and Insulin Resistance: A Randomized, Feeding, Equivalence Trial

Psychological resilience in older adults with type 2 diabetes from the Look AHEAD Trial

BackgroundThere is growing interest in identifying factors associated with healthy aging. This cross-sectional study evaluated associations of psychological resilience with factors associated with aging in older adults with type 2 diabetes mellitus (T2DM).MethodsParticipants were 3199 adults (72.2 ± 6.2 years of age, 61% female, 61% White, body mass index [BMI] = 34.2 ± 8.2 kg/m2) with T2DM enrolled in Look AHEAD (a multi-site… Continue reading Psychological resilience in older adults with type 2 diabetes from the Look AHEAD Trial

Weight loss strategies, weight change, and type 2 diabetes in US health professionals: A cohort study

BackgroundWeight loss is crucial for disease prevention among individuals with overweight or obesity. This study aimed to examine associations of weight loss strategies (WLSs) with weight change and type 2 diabetes (T2D) risk among US health professionals.Methods and findingsThis study included 93,110 participants (24 to 60 years old; 11.6% male) from the Nurses’ Health Study… Continue reading Weight loss strategies, weight change, and type 2 diabetes in US health professionals: A cohort study

Diabetes and Obesity in Down Syndrome Across the Lifespan: A Retrospective Cohort Study Using U.K. Electronic Health Records

Down syndrome (DS) is the most common form of chromosomal trisomy. Genetic factors in DS may increase the risk for diabetes. This study aimed to determine whether DS is associated with an increased incidence of diabetes and the relationship with obesity across the life span compared with control patients.RESEARCH DESIGN AND METHODSThis matched population–based cohort… Continue reading Diabetes and Obesity in Down Syndrome Across the Lifespan: A Retrospective Cohort Study Using U.K. Electronic Health Records