The association between serum folate deficiency and the risk of dementia in old age is unclear, perhaps owing to small sample sizes, the competing risk of mortality or reverse causation. Objective To examine the associations between serum folate deficiency and the risks of incident dementia and all-cause mortality in a large national sample of older… Continue reading Serum folate deficiency and the risks of dementia and all-cause mortality: a national study of old age
Tag: Dementia
Longitudinal Associations of Mental Disorders With Dementia30-Year Analysis of 1.7 Million New Zealand Citizens
Mental disorders are an underappreciated category of modifiable risk factors for dementia. Developing an evidence base about the link between mental disorders and dementia risk requires studies that use large, representative samples, consider the full range of psychiatric conditions, ascertain mental disorders from early life, use long follow-ups, and distinguish between Alzheimer disease and related… Continue reading Longitudinal Associations of Mental Disorders With Dementia30-Year Analysis of 1.7 Million New Zealand Citizens
Association of Loneliness With 10-Year Dementia Risk and Early Markers of Vulnerability for Neurocognitive Decline
Background and Objective: Loneliness is common and its prevalence is rising. The relationship of loneliness with subsequent dementia and the early preclinical course of Alzheimer disease and related dementia (ADRD) remains unclear. Thus, the primary objective of this study was to determine the association of loneliness with 10-year all-cause dementia risk and early cognitive and… Continue reading Association of Loneliness With 10-Year Dementia Risk and Early Markers of Vulnerability for Neurocognitive Decline
Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019
SummaryBackgroundGiven the projected trends in population ageing and population growth, the number of people with dementia is expected to increase. In addition, strong evidence has emerged supporting the importance of potentially modifiable risk factors for dementia. Characterising the distribution and magnitude of anticipated growth is crucial for public health planning and resource prioritisation. This study… Continue reading Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019
Frailty, lifestyle, genetics and dementia risk
To optimise dementia prevention strategies, we must understand the complex relationships between lifestyle behaviours, frailty and genetics. Methods We explored relationships between frailty index, healthy lifestyle and polygenic risk scores (all assessed at study entry) and incident all-cause dementia as recorded on hospital admission records and death register data. Results The analytical sample had a… Continue reading Frailty, lifestyle, genetics and dementia risk
Association of Physical Activity Level With Risk of Dementia in a Nationwide Cohort in Korea
Current guidelines recommend 500 to 999 metabolic equivalent (MET)–minutes per week (MET-min/wk) of regular physical activity. However, evidence regarding the association between light-intensity physical activity (LPA) and dementia in older adults is inconsistent. Objective To assess the association between physical activity and new-onset dementia, focusing on the dose-response association between physical activity and dementia and… Continue reading Association of Physical Activity Level With Risk of Dementia in a Nationwide Cohort in Korea
Association of resting heart rate with cognitive decline and dementia in older adults: A population-based cohort study
Resting heart rate (RHR) predicts future risk for cardiovascular disease (CVD). However, longitudinal studies investigating the relationship of RHR with cognitive decline are scarce. Methods: This population-based cohort study included 2147 participants (age≥60) in SNAC-K who were free of dementia and regularly followed from 2001–2004 to 2013–2016. RHR was assessed with electrocardiogram. Dementia was diagnosed… Continue reading Association of resting heart rate with cognitive decline and dementia in older adults: A population-based cohort study
Amateur Boxing and DementiaCognitive Impairment Within the 35-Year Caerphilly Cohort Study
Objective:To examine the long-term effects of amateur boxing in a representative population sample of men. Design:The sample was examined every 5 years for 35 years. Cognition was assessed repeatedly from the third examination. Previous boxing experience and dementia were assessed at the fifth examination, and dementia assessed subsequently through medical records. Setting and Assessment of… Continue reading Amateur Boxing and DementiaCognitive Impairment Within the 35-Year Caerphilly Cohort Study
Consumption of coffee and tea and risk of developing stroke, dementia, and poststroke dementia: A cohort study in the UK Biobank
Previous studies have revealed the involvement of coffee and tea in the development of stroke and dementia. However, little is known about the association between the combination of coffee and tea and the risk of stroke, dementia, and poststroke dementia. Therefore, we aimed to investigate the associations of coffee and tea separately and in combination… Continue reading Consumption of coffee and tea and risk of developing stroke, dementia, and poststroke dementia: A cohort study in the UK Biobank
2 Medical News 