#C-reactive protein and #cardiovascular risk among #women with no standard modifiable risk factors: evaluating the ‘SMuRF-less but inflamed’

Interventions in preventive cardiology traditionally focus on four standard modifiable cardiovascular risk factors (SMuRFs): hypertension, dyslipidaemia, diabetes mellitus, and smoking. Yet, a substantial proportion of incident cardiovascular events accrues for individuals with none of these factors, particularly among women for whom cardiovascular disease remains under-detected and under-treated. The utility of the inflammatory biomarker high-sensitivity C-reactive… Continue reading #C-reactive protein and #cardiovascular risk among #women with no standard modifiable risk factors: evaluating the ‘SMuRF-less but inflamed’

Low High‐Sensitivity C‐ #Reactive Protein Level in Korean Patients With Chronic #Kidney Disease and Its Predictive Significance for Cardiovascular Events, Mortality, and Adverse Kidney Outcomes: Results From KNOW‐CKD

Inflammation levels are lower in East Asians than in Western people. We studied the association between high‐sensitivity hs‐CRP (C‐reactive protein) and adverse outcomes in Korean patients with chronic kidney disease. Methods and Results We included 2018 participants from the KNOW‐CKD (Korean Cohort Study for Outcome in Patients With Chronic Kidney Disease) between April 2011 and… Continue reading Low High‐Sensitivity C‐ #Reactive Protein Level in Korean Patients With Chronic #Kidney Disease and Its Predictive Significance for Cardiovascular Events, Mortality, and Adverse Kidney Outcomes: Results From KNOW‐CKD

Relationship of #Nutritional Status, #Inflammation, and Serum #Albumin Levels During Acute Illness: A Prospective Study

Low serum albumin levels resulting from inflammation-induced capillary leakage or disease-related anorexia during acute illness are associated with poor outcomes. We investigated the relationship of nutritional status and inflammation with low serum albumin levels and 30-day mortality in a large cohort.. Among the 2465 patients, 1019 (41%) had low serum albumin levels (<34 g/L), 619… Continue reading Relationship of #Nutritional Status, #Inflammation, and Serum #Albumin Levels During Acute Illness: A Prospective Study

#C-reactive protein mediates the association between leisure-time physical #activity and #lung function in middle-aged and older adults

Although previous studies have reported the benefits of physical activity (PA) to lung function in middle-aged and older adults, the biological mechanisms are still unclear.. ..Multiple linear regression models suggested that higher PA was associated with lower levels of CRP (β = − 0.048, P = 0.002 for moderate PA; β = − 0.108, P < 0.001 for high PA). CRP negatively correlated with FEV1… Continue reading #C-reactive protein mediates the association between leisure-time physical #activity and #lung function in middle-aged and older adults

Prediction model for #pneumonia in primary care patients with an acute respiratory tract infection: role of symptoms, signs, and biomarkers

Diagnosing pneumonia can be challenging in general practice but is essential to distinguish from other respiratory tract infections because of treatment choice and outcome prediction.. ..Two hundred forty-nine patients were included of whom 30 (12%) displayed a consolidation on chest X ray. Absence of runny nose and whether or not a patient felt ill were… Continue reading Prediction model for #pneumonia in primary care patients with an acute respiratory tract infection: role of symptoms, signs, and biomarkers

C-Reactive Protein Testing to Guide Antibiotic Prescribing for #COPD Exacerbations

Point-of-care testing of C-reactive protein (#CRP) may be a way to reduce unnecessary use of antibiotics without harming patients who have acute exacerbations of chronic obstructive pulmonary disease (COPD). A lower percentage of patients in the CRP-guided group than in the usual-care group received an antibiotic prescription at the initial consultation (47.7% vs. 69.7%, for… Continue reading C-Reactive Protein Testing to Guide Antibiotic Prescribing for #COPD Exacerbations