Background: The Hiroshima Registry for Evaluation and Treatment of Nocturnal and Early Morning Hypertension (Hiroshima NOCTURNE) was a prospective, multicenter study designed to determine whether elevated nighttime blood pressure (BP), assessed using a home BP monitoring (HBPM) device, can be normalized through active antihypertensive therapy in patients already receiving antihypertensive medication. In this subanalysis, we… Continue reading Factors associated with the failure to achieve nocturnal blood #pressure control
Tag: circadian
Later #eating #timing in relation to an individual internal clock is associated with lower #insulin sensitivity and affected by genetic factors
BackgroundAlthough the contribution of the circadian clock to metabolic regulation is widely recognized, the role of eating timing in glucose metabolism and diabetes risk remains insufficiently studied. This study aimed (i) to investigate the link between the eating timing pattern relative to individual clock and glucose homoeostasis and (ii) to explore the contribution of genetic… Continue reading Later #eating #timing in relation to an individual internal clock is associated with lower #insulin sensitivity and affected by genetic factors
Impact of #lifestyle moderate-to-vigorous #physical activity timing on #glycemic control in sedentary adults with #overweight/obesity and metabolic impairments
ObjectiveModerate-to-vigorous physical activity (MVPA) improves glucose levels; however, whether its timing affects daily glycemic control remains unclear. This study aims to investigate the impact of lifestyle MVPA timing on daily glycemic control in sedentary adults with overweight/obesity and metabolic impairments.MethodsA total of 186 adults (50% women; age, 46.8 [SD 6.2] years) with overweight/obesity (BMI, 32.9… Continue reading Impact of #lifestyle moderate-to-vigorous #physical activity timing on #glycemic control in sedentary adults with #overweight/obesity and metabolic impairments
Effect of timed dosing of usual #antihypertensives according to patient chronotype on #cardiovascular outcomes: the Chronotype sub-study cohort of the Treatment in Morning versus Evening (TIME) study
BackgroundTiming drug administration to endogenous circadian rhythms may enhance treatment efficacy. In the Chronotype sub-study of the Treatment in Morning versus Evening (TIME) clinical trial we examined whether timing of usual antihypertensive medications according to patient chronotype (a behavioural marker of personal circadian rhythm) may influence clinical cardiovascular outcomes.MethodsThis was a cohort sub-study of TIME,… Continue reading Effect of timed dosing of usual #antihypertensives according to patient chronotype on #cardiovascular outcomes: the Chronotype sub-study cohort of the Treatment in Morning versus Evening (TIME) study
Effects of calibrated blue–yellow changes in light on the human #circadian clock
Evening exposure to short-wavelength light can affect the circadian clock, sleep and alertness. Intrinsically photosensitive retinal ganglion cells expressing melanopsin are thought to be the primary drivers of these effects. Whether colour-sensitive cones also contribute is unclear. Here, using calibrated silent-substitution changes in light colour along the blue–yellow axis, we investigated whether mechanisms of colour… Continue reading Effects of calibrated blue–yellow changes in light on the human #circadian clock
Dietary #circadian rhythms and #cardiovascular disease risk in the prospective NutriNet-Santé cohort
Dietary circadian rhythms and #cardiovascular disease risk in the prospective NutriNet-Santé cohortDaily eating/fasting cycles synchronise circadian peripheral clocks, involved in the regulation of the cardiovascular system. However, the associations of daily meal and fasting timing with cardiovascular disease (CVD) incidence remain unclear. We used data from 103,389 adults in the NutriNet-Santé study. Meal timing and… Continue reading Dietary #circadian rhythms and #cardiovascular disease risk in the prospective NutriNet-Santé cohort
Can Circadian Eating Pattern Adjustments Reduce Risk or Prevent Development of T2D?
Type 2 diabetes (T2D) is a chronic condition that occurs in insulin-resistant people with reduced glucose uptake. It is contributed to and exacerbated by a poor diet that results in accumulation of adipose tissue, high blood sugar, and other metabolic issues. Because humans have undergone food scarcity throughout history, our species has adapted a fat… Continue reading Can Circadian Eating Pattern Adjustments Reduce Risk or Prevent Development of T2D?
META-ANALYSIS: CLUSTER HEADACHE, MIGRAINE HAVE STRONG LINKS TO CIRCADIAN SYSTEM
...For cluster headache, the meta-analysis found a circadian pattern of headache attacks in 71% of people. Attacks peaked in the late hours of the night to early hours of the morning. During the year, people had more attacks in the spring and fall. On the genetic level, cluster headache was associated with two main circadian… Continue reading META-ANALYSIS: CLUSTER HEADACHE, MIGRAINE HAVE STRONG LINKS TO CIRCADIAN SYSTEM
The hidden link between circadian entropy and mental health disorders
The high overlapping nature of various features across multiple mental health disorders suggests the existence of common psychopathology factor(s) (p-factors) that mediate similar phenotypic presentations across distinct but relatable disorders. In this perspective, we argue that circadian rhythm disruption (CRD) is a common underlying p-factor that bridges across mental health disorders within their age and… Continue reading The hidden link between circadian entropy and mental health disorders
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