Our brain continuously receives signals from the body and the environment. Although we are mostly unaware of internal bodily processes, such as our heartbeats, they can affect our perception. Here, we show two distinct ways in which the heartbeat modulates conscious perception. First, increased heartbeat-evoked neural activity before stimulation is followed by decreased somatosensory detection.… Continue reading Heart–brain interactions shape somatosensory perception and evoked potentials
A human monoclonal antibody blocking SARS-CoV-2 infection
The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV) in cell culture. This cross-neutralizing antibody targets a communal epitope on… Continue reading A human monoclonal antibody blocking SARS-CoV-2 infection
The Possible Role of Vitamin #D in Suppressing Cytokine Storm and Associated Mortality in #COVID-19 Patients
Large-scale data show that the mortality of COVID-19 varies dramatically across populations, although the cause of these disparities is not well understood. In this study we investigated whether severe COVID-19 is linked to Vitamin D (Vit D) deficiency. Method Daily admission, recovery and deceased rate data for patients with COVID-19 from countries with a large… Continue reading The Possible Role of Vitamin #D in Suppressing Cytokine Storm and Associated Mortality in #COVID-19 Patients
#Olive Oil Consumption and Cardiovascular Risk in U.S. Adults
Olive oil intake has been associated with lower risk of cardiovascular disease (CVD) in Mediterranean populations, but little is known about these associations in the U.S population.. ..During 24 years of follow-up, this study documented 9,797 incident cases of CVD, including 6,034 CHD cases and 3,802 stroke cases. After adjusting for major diet and lifestyle… Continue reading #Olive Oil Consumption and Cardiovascular Risk in U.S. Adults
Right Ventricular Global Longitudinal Strain and Outcomes in Heart Failure with Preserved Ejection Fraction
Right ventricular (RV) strain has emerged as an accurate tool for RV function assessment and is a powerful predictor of survival in patients with heart failure with reduced ejection fraction. However, its prognostic impact in patients with heart failure with preserved ejection fraction (HFpEF) remains unclear. The aim of this study was to compare the… Continue reading Right Ventricular Global Longitudinal Strain and Outcomes in Heart Failure with Preserved Ejection Fraction
Dietary Intake of #Acrylamide and Risk of Breast, Endometrial, and Ovarian Cancers: A Systematic Review and Dose–Response Meta-analysis
Acrylamide is a probable human carcinogen. Aside from occupational exposures and smoking, diet is the main source of exposure in humans. We performed a systematic review of the association between estimated dietary intake of acrylamide and risk of female breast, endometrial, and ovarian cancers in nonexperimental studies published through February 25, 2020, and conducted a… Continue reading Dietary Intake of #Acrylamide and Risk of Breast, Endometrial, and Ovarian Cancers: A Systematic Review and Dose–Response Meta-analysis
Associations between the National Walkability Index and #walking among US Adults — National Health Interview Survey, 2015
The Environmental Protection Agency created the National Walkability Index (Index) to compare and analyze walkability among US communities. Index elements include design, distance to transit, and diversity of land uses. Associations between the Index and walking behavior have not been examined. This study describes associations between the Index and transportation and leisure walking among US… Continue reading Associations between the National Walkability Index and #walking among US Adults — National Health Interview Survey, 2015
Neuroinflammation in Alzheimer’s Disease: Friend or Foe?
Neuroinflammation is part of the complex immune response within the central nervous system (CNS), whose details have been partially elucidated. The CNS immune response involves elements carried from the periphery and resident elements, mainly represented by glial cells. These cells drive neuroinflammation, which can be roughly defined as an articulated physiological response characterized by the… Continue reading Neuroinflammation in Alzheimer’s Disease: Friend or Foe?
The associations of longitudinal changes in consumption of total and types of #dairy products and markers of metabolic risk and #adiposity: findings from the European Investigation into Cancer and Nutrition (EPIC)–Norfolk study, United Kingdom
..For adiposity, an increase in fermented dairy products [yogurt (total or low-fat) or low-fat cheese] consumption was associated with a lower increase in body weight and body mass index (BMI). For example, over 3.7 y, increasing yogurt consumption by 1 serving/d was associated with a smaller increase in body weight by 0.23 kg (95% CI:… Continue reading The associations of longitudinal changes in consumption of total and types of #dairy products and markers of metabolic risk and #adiposity: findings from the European Investigation into Cancer and Nutrition (EPIC)–Norfolk study, United Kingdom