Antibiotic over prescription for upper respiratory tract infections (URTIs) in primary care exacerbates antimicrobial resistance. There is a need for effective alternatives to antibiotic prescribing. Honey is a lay remedy for URTIs, and has an emerging evidence base for its use. Honey has antimicrobial properties, and guidelines recommended honey for acute cough in children.. ..We… Continue reading Effectiveness of #honey for symptomatic relief in upper #respiratory tract infections: a systematic review and meta-analysis
Effects of #Diet versus Gastric #Bypass on Metabolic Function in Diabetes
Some studies have suggested that in people with type 2 diabetes, Roux-en-Y gastric bypass has therapeutic effects on metabolic function that are independent of weight loss.. ..Weight loss was associated with increases in mean suppression of glucose production from baseline, by 7.04 μmol per kilogram of fat-free mass per minute (95% confidence interval [CI], 4.74… Continue reading Effects of #Diet versus Gastric #Bypass on Metabolic Function in Diabetes
#Migraine, obesity and body #fat distribution – a population-based study
Obesity has been linked to an increased prevalence of migraine, and to increased migraine attack frequency, but several questions are left unanswered by previous studies. We examined the relationship between obesity and headache in a large, population-based study where we could take into account body fat distribution, migraine subtypes and tension-type headache.. ..Both total body… Continue reading #Migraine, obesity and body #fat distribution – a population-based study
Clinical Course and Molecular Viral Shedding Among Asymptomatic and Symptomatic Patients With #SARS-CoV-2 Infection in a Community Treatment Center in the Republic of Korea
There is limited information about the clinical course and viral load in asymptomatic patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).. Epidemiologic, demographic, and laboratory data were collected and analyzed. Attending health care personnel carefully identified patients’ symptoms during isolation. The decision to release an individual from isolation was based on the results… Continue reading Clinical Course and Molecular Viral Shedding Among Asymptomatic and Symptomatic Patients With #SARS-CoV-2 Infection in a Community Treatment Center in the Republic of Korea
Increasing Emergency Department Visits for #Mental Health Conditions in the United States
..Nationally representative samples of ED visits in the United States were assessed using a repeated cross-sectional analysis of National Hospital Ambulatory Medical Care Survey data. This study used diagnoses associated with each ED visit to identify changes in proportions in mental health diagnostic categories (psychiatric diagnoses only, substance use–related diagnoses only, or both, based on… Continue reading Increasing Emergency Department Visits for #Mental Health Conditions in the United States
An electrophysiological marker of #arousal level in humans
Deep non-rapid eye movement sleep (NREM) and general anesthesia with propofol are prominent states of reduced arousal linked to the occurrence of synchronized oscillations in the electroencephalogram (EEG). Although rapid eye movement (REM) sleep is also associated with diminished arousal levels, it is characterized by a desynchronized, ‘wake-like’ EEG. This observation implies that reduced arousal… Continue reading An electrophysiological marker of #arousal level in humans
CMS121, a fatty acid synthase inhibitor, protects against excess lipid peroxidation and inflammation and alleviates cognitive loss in a transgenic mouse model of #Alzheimer’s disease
The oxidative degradation of lipids has been shown to be implicated in the progression of several neurodegenerative diseases and modulating lipid peroxidation may be efficacious for treating Alzheimer’s disease (AD). This hypothesis is strengthened by recent findings suggesting that oxytosis/ferroptosis, a cell death process characterized by increased lipid peroxidation, plays an important role in AD-related… Continue reading CMS121, a fatty acid synthase inhibitor, protects against excess lipid peroxidation and inflammation and alleviates cognitive loss in a transgenic mouse model of #Alzheimer’s disease
Vitamin #D for treatment of non‐alcoholic #fatty liver disease detected by transient elastography: A randomized, double‐blind, placebo‐controlled trial
To evaluate the effects of vitamin D on transient elastography (TE, FibroScan) indices of liver steatosis (controlled attenuation parameter [CAP]) and fibrosis (liver stiffness measurement [LSM]) in adults with non‐alcoholic fatty liver disease (NAFLD).. ..Both CAP and LSM gradually decreased in vitamin D‐treated patients and slightly increased in the placebo arm. Vitamin D was superior… Continue reading Vitamin #D for treatment of non‐alcoholic #fatty liver disease detected by transient elastography: A randomized, double‐blind, placebo‐controlled trial
Association Between the Gut #Microbiota and Blood #Pressure in a Population Cohort of 6953 Individuals
Several small‐scale animal studies have suggested that gut microbiota and blood pressure (BP) are linked. However, results from human studies remain scarce and conflicting. We wanted to elucidate the multivariable‐adjusted association between gut metagenome and BP in a large, representative, well‐phenotyped population sample. We performed a focused analysis to examine the previously reported inverse associations… Continue reading Association Between the Gut #Microbiota and Blood #Pressure in a Population Cohort of 6953 Individuals
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