In the Recommendation Statement published in this issue of JAMA,1 the US Preventive Services Task Force (USPTF) has reaffirmed its 2014 recommendation, stating that “The USPTF recommends against screening for asymptomatic carotid artery stenosis in the general adult population (D recommendation),” based on evidence that the harms of screening for carotid artery stenosis in asymptomatic… Continue reading Screening for Asymptomatic #Carotid #Artery Stenosis Lack of Clinical Benefit, Potential for Harm
Time-restricted #feeding normalizes hyperinsulinemia to inhibit #breast cancer in obese postmenopausal mouse models
Accumulating evidence indicates that obesity with its associated metabolic dysregulation, including hyperinsulinemia and aberrant circadian rhythms, increases the risk for a variety of cancers including postmenopausal breast cancer. Caloric restriction can ameliorate the harmful metabolic effects of obesity and inhibit cancer progression but is difficult to implement and maintain outside of the clinic. In this… Continue reading Time-restricted #feeding normalizes hyperinsulinemia to inhibit #breast cancer in obese postmenopausal mouse models
Association of Medical #Stimulants With #Mortality in the US From 2010 to 2017
The role of nonopioids in the drug overdose epidemic in the US is frequently overshadowed. From 2015 to 2016, mortality rates involving cocaine and psychostimulants were smaller than opioids, but were rising faster than opioids.1 We examined individual substances listed on death certificates to better understand stimulant-associated mortality and assess rates over time. https://bit.ly/3oEgFbP
Increased #alcohol use during the #COVID-19 pandemic: The effect of mental health and age in a cross-sectional sample of social media users in the U.S.
The COVID-19 pandemic has triggered a public health crisis of unprecedented scale. Increased alcohol use has been extensively documented during other crises, particularly among persons with anxiety and depression. Despite COVID-19's differential impact by age, the association of age, mental health and alcohol use during the pandemic has not been explored. This study aimed to… Continue reading Increased #alcohol use during the #COVID-19 pandemic: The effect of mental health and age in a cross-sectional sample of social media users in the U.S.
The Tailgate Study: Differing #metabolic effects of a bout of excessive #eating and #drinking
Excess energy intake by spectators at a sporting event (i.e., a tailgate) might cause acute negative health effects. However, limited data exist regarding the effects of overeating and alcohol consumption on lipid metabolism and the potential to gain intrahepatic triacylglycerols (IHTG). We tested the hypothesis that overconsumption of food and alcohol would significantly increase both… Continue reading The Tailgate Study: Differing #metabolic effects of a bout of excessive #eating and #drinking
Association between current medication use and progression of radiographic #knee #osteoarthritis: data from the Osteoarthritis Initiative
Use of specific medications may accelerate the progression of radiographic knee osteoarthritis (RKOA). Our aim was to examine the effect of medication use on the progression of RKOA. Methods We used longitudinal data from the Osteoarthritis Initiative (OAI); an observational study of risk factors for knee OA. At baseline, we selected participants with RKOA (KL… Continue reading Association between current medication use and progression of radiographic #knee #osteoarthritis: data from the Osteoarthritis Initiative
A Little #Autonomy Support Goes a Long Way: Daily Autonomy‐Supportive Parenting, Child Well‐Being, Parental Need Fulfillment, and Change in Child, Family, and Parent Adjustment Across the Adaptation to the #COVID‐19 Pandemic
This study examined the effects of daily parental autonomy support on changes in child behavior, family environment, and parental well‐being across 3 weeks during the COVID‐19 pandemic in Germany. Day‐to‐day associations among autonomy‐supportive parenting, parental need fulfillment, and child well‐being were also assessed. Parents (longitudinal N = 469; Mage = 42.93, SDage = 6.40) of… Continue reading A Little #Autonomy Support Goes a Long Way: Daily Autonomy‐Supportive Parenting, Child Well‐Being, Parental Need Fulfillment, and Change in Child, Family, and Parent Adjustment Across the Adaptation to the #COVID‐19 Pandemic
Incidence, Prevalence and Healthcare Outcomes in Idiopathic #Intracranial #Hypertension: A Population Study
To characterise trends in incidence, prevalence, and healthcare outcomes in the idiopathic intracranial hypertension (IIH) population in Wales using routinely collected healthcare data. Methods: We used and validated primary and secondary care IIH diagnosis codes within the Secure Anonymised Information Linkage databank, to ascertain IIH cases and controls, in a retrospective cohort study between 2003… Continue reading Incidence, Prevalence and Healthcare Outcomes in Idiopathic #Intracranial #Hypertension: A Population Study
Individualizing Surveillance #Mammography for Older Patients After Treatment for Early-Stage #Breast Cancer Multidisciplinary Expert Panel and International Society of Geriatric Oncology Consensus Statement
..After a literature review of the risk of ipsilateral and contralateral breast cancer events among breast cancer survivors and the harms and benefits associated with mammography, a multidisciplinary expert panel was convened to develop consensus guidelines on surveillance mammography for breast cancer survivors 75 years or older. Using an iterative consensus-based approach, input from clinician… Continue reading Individualizing Surveillance #Mammography for Older Patients After Treatment for Early-Stage #Breast Cancer Multidisciplinary Expert Panel and International Society of Geriatric Oncology Consensus Statement
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