Stang and coworkers have recently reported in the Journal that “RT-PCR test results as gold standard for assessing and controlling infectiousness fail”[1]. The authors analyzed two scenarios and used Ct25 and Ct30 as thresholds for infectiousness and conclude that more than the half of their patient cohort was unlikely to have been infectious, i.e. the… Continue reading Limited protection against #SARS-CoV-2 infection and virus transmission after mRNA #vaccination
Pilot randomized controlled trial of a #hypnosis intervention for women with #bladder pain syndrome
To evaluate the feasibility and acceptability of a randomized controlled trial of a hypnosis intervention for the treatment of bladder pain syndrome/interstitial cystitis (BPS/IC) in women. MethodsWe conducted a parallel arm, non-blinded, pilot randomized controlled trial of standardized hypnosis sessions including a hypnosis web tool versus usual care in adult women with BPS/IC. Pilot study… Continue reading Pilot randomized controlled trial of a #hypnosis intervention for women with #bladder pain syndrome
Association of poor #housing conditions with #COVID-19 incidence and mortality across US counties
Poor housing conditions have been linked with worse health outcomes and infectious disease spread. Since the relationship of poor housing conditions with incidence and mortality of COVID-19 is unknown, we investigated the association between poor housing condition and COVID-19 incidence and mortality in US counties. MethodsWe conducted cross-sectional analysis of county-level data from the US… Continue reading Association of poor #housing conditions with #COVID-19 incidence and mortality across US counties
Topical 5% #Tranexamic acid with 30% #Glycolic acid peel: An useful Combination for Accelerating the improvement in #Melasma
Recently, topical Tranexamic acid (TXA) has been used in melasma management. On detail search of literature, this may be the first study assessing efficacy on combining of Topical TXA with GA peel in melasma. To assess efficacy, safety and improvement in quality of life index on combining 30% GA peel with 5% TXA solution topically… Continue reading Topical 5% #Tranexamic acid with 30% #Glycolic acid peel: An useful Combination for Accelerating the improvement in #Melasma
First #monoclonal antibody treatment for #COVID-19 approved for use in the UK
Following on from a thorough review of the evidence carried out by the MHRA, and recommendation by the Commission on Human Medicines (CHM), the government’s independent expert scientific advisory body, the MHRA has approved Ronapreve as the first monoclonal antibody combination product indicated for use in the prevention and treatment of acute COVID-19 infection for… Continue reading First #monoclonal antibody treatment for #COVID-19 approved for use in the UK
Enteric-Coated #Aspirin and the Risk of Gastrointestinal Side Effects: A Systematic Review
Aspirin appeared as a medicine to deal with aches and inflammation, but due to its antiplatelet properties, it has evolved into a drug mainly used to avert cardiovascular disease. Regardless of its therapeutic uses, the limiting aspect for aspirin use has been its affiliation with gastrointestinal (GI) toxicity, classifying from acute mucosal damage to GI… Continue reading Enteric-Coated #Aspirin and the Risk of Gastrointestinal Side Effects: A Systematic Review
Microbial Diversity and Abundance of Parabacteroides Mediate the Associations Between Higher Intake of #Flavonoid-Rich Foods and Lower Blood #Pressure
We assessed, for the first time, to what extent the composition of the gut microbiome might explain the cross-sectional association of habitual flavonoid and flavonoid-rich food intake with systolic and diastolic blood pressure (BP) in a community-based sample (N=904) from Northern Germany. Gut microbiome composition was sequenced from 16S ribosomal RNA genes. Higher total flavonoid… Continue reading Microbial Diversity and Abundance of Parabacteroides Mediate the Associations Between Higher Intake of #Flavonoid-Rich Foods and Lower Blood #Pressure
#Cognitive stimulation in the workplace, plasma proteins, and risk of #dementia: three analyses of population cohort studies
To examine the association between cognitively stimulating work and subsequent risk of dementia and to identify protein pathways for this association. Design Multicohort study with three sets of analyses. Setting United Kingdom, Europe, and the United States. Participants Three associations were examined: cognitive stimulation and dementia risk in 107 896 participants from seven population based prospective… Continue reading #Cognitive stimulation in the workplace, plasma proteins, and risk of #dementia: three analyses of population cohort studies
The association between occupational #asbestos exposure with the risk of incidence and mortality from #prostate #cancer: a systematic review and meta-analysis
There is conflicting evidence on the association between asbestos exposure and prostate cancer (PCa). Two recent meta-analyses have claimed that exposure is associated with increased PCa incidence and mortality, but they suffer from some methodological flaws. Given the potential importance of this research question, we aimed to perform a methodologically sound systematic review and meta-analysis… Continue reading The association between occupational #asbestos exposure with the risk of incidence and mortality from #prostate #cancer: a systematic review and meta-analysis
2 Medical News 