Mindfulness witnessed a substantial popularity surge in the past decade, especially as digitally self-administered interventions became available at relatively low costs. Yet, it is uncertain whether they effectively help reduce stress. In a preregistered (OSF https://doi.org/10.17605/OSF.IO/UF4JZ; retrospective registration at ClinicalTrials.gov NCT06308744) multi-site study (nsites = 37, nparticipants = 2,239, 70.4% women, Mage = 22.4, s.d.age = 10.1, all fluent English speakers), we experimentally tested whether four single,… Continue reading Self-administered #mindfulness interventions reduce #stress in a large, randomized controlled multi-site study
Category: Psychiatry
#High-fat diet, #microbiome-gut-brain axis signaling, and #anxiety-like behavior in male rats
Obesity, associated with the intake of a high-fat diet (HFD), and anxiety are common among those living in modern urban societies. Recent studies suggest a role of microbiome-gut-brain axis signaling, including a role for brain serotonergic systems in the relationship between HFD and anxiety. Evidence suggests the gut microbiome and the serotonergic brain system together… Continue reading #High-fat diet, #microbiome-gut-brain axis signaling, and #anxiety-like behavior in male rats
Personalized brain circuit scores identify clinically distinct biotypes in #depression and #anxiety
There is an urgent need to derive quantitative measures based on coherent neurobiological dysfunctions or ‘biotypes’ to enable stratification of patients with depression and anxiety. We used task-free and task-evoked data from a standardized functional magnetic resonance imaging protocol conducted across multiple studies in patients with depression and anxiety when treatment free (n = 801) and after… Continue reading Personalized brain circuit scores identify clinically distinct biotypes in #depression and #anxiety
National Trends in Emergency Department Visits for #Suicide Attempts and Intentional #Self-Harm
Objective:This study estimated national annual trends and characteristics of emergency department visits for suicide attempts and intentional self-harm in the United States from 2011 to 2020.Methods:Data were from the National Hospital Ambulatory Medical Care Survey, an annual cross-sectional national sample survey of emergency departments. Visits for suicide attempts and intentional self-harm were identified using discharge… Continue reading National Trends in Emergency Department Visits for #Suicide Attempts and Intentional #Self-Harm
#Bartonella species bacteremia in association with adult #psychosis
Introduction: The potential role of pathogens, particularly vector-transmitted infectious agents, as a cause of psychosis has not been intensively investigated. We have reported a potential link between Bartonella spp. bacteremia and neuropsychiatric symptoms, including pediatric acute onset neuropsychiatric syndrome and schizophrenia. The purpose of this study was to further assess whether Bartonella spp. exposure or infection are associated with psychosis.Methods: In… Continue reading #Bartonella species bacteremia in association with adult #psychosis
#Omega-3 supplementation reduces aggressive #behavior: A meta-analytic review of randomized controlled trials
AbstractThere is increasing interest in the use of omega-3 supplements to reduce aggressive behavior. This meta-analysis summarizes findings from 29 RCTs (randomized controlled trials) on omega-3 supplementation to reduce aggression, yielding 35 independent samples with a total of 3918 participants. Three analyses were conducted where the unit of analysis was independent samples, independent studies, and… Continue reading #Omega-3 supplementation reduces aggressive #behavior: A meta-analytic review of randomized controlled trials
#Neuropsychiatric prodromes and symptom timings in relation to disease onset and/or flares in #SLE: results from the mixed methods international INSPIRE study
BackgroundNeuropsychiatric symptoms in SLE and other systemic autoimmune rheumatic diseases (SARDs) are challenging to diagnose, attribute and manage. We investigated the timings of onset of a broad range of neuropsychiatric (NP) symptoms in relation to timing of SLE onset. In addition, we explored whether NP symptoms may be a prodrome to SARD onset and to… Continue reading #Neuropsychiatric prodromes and symptom timings in relation to disease onset and/or flares in #SLE: results from the mixed methods international INSPIRE study
Age-dependent association of #cannabis use with risk of #psychotic disorder
BackgroundEpidemiologic research suggests that youth cannabis use is associated with psychotic disorders. However, current evidence is based heavily on 20th-century data when cannabis was substantially less potent than today.MethodsWe linked population-based survey data from 2009 to 2012 with records of health services covered under universal healthcare in Ontario, Canada, up to 2018. The cohort included… Continue reading Age-dependent association of #cannabis use with risk of #psychotic disorder
#Mortality Risk Among Women With #Premenstrual Disorders in Sweden
Key PointsQuestion Do women with premenstrual disorders (PMDs) have higher risks of all-cause and cause-specific mortality compared with women without PMDs?Findings This nationwide matched cohort study of 406 488 women in Sweden during a mean (SD) follow-up of 6.2 (4.6) years (range, 1-18 years) revealed that overall, women with diagnosed PMDs did not have an increased risk of… Continue reading #Mortality Risk Among Women With #Premenstrual Disorders in Sweden
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