Association Between Screen Time Exposure in Children at 1 Year of Age and Autism Spectrum Disorder at 3 Years of AgeThe Japan Environment and Children’s Study

It is unclear to what extent the duration of screen time in infancy is associated with the subsequent diagnosis of autism spectrum disorder. Objective To examine the association between screen time in infancy and the development of autism spectrum disorder at 3 years of age. Design, Setting, and Participants This cohort study analyzed data from… Continue reading Association Between Screen Time Exposure in Children at 1 Year of Age and Autism Spectrum Disorder at 3 Years of AgeThe Japan Environment and Children’s Study

Longitudinal Associations of Mental Disorders With Dementia30-Year Analysis of 1.7 Million New Zealand Citizens

Mental disorders are an underappreciated category of modifiable risk factors for dementia. Developing an evidence base about the link between mental disorders and dementia risk requires studies that use large, representative samples, consider the full range of psychiatric conditions, ascertain mental disorders from early life, use long follow-ups, and distinguish between Alzheimer disease and related… Continue reading Longitudinal Associations of Mental Disorders With Dementia30-Year Analysis of 1.7 Million New Zealand Citizens

Association of Loneliness With 10-Year Dementia Risk and Early Markers of Vulnerability for Neurocognitive Decline

Background and Objective: Loneliness is common and its prevalence is rising. The relationship of loneliness with subsequent dementia and the early preclinical course of Alzheimer disease and related dementia (ADRD) remains unclear. Thus, the primary objective of this study was to determine the association of loneliness with 10-year all-cause dementia risk and early cognitive and… Continue reading Association of Loneliness With 10-Year Dementia Risk and Early Markers of Vulnerability for Neurocognitive Decline

Adolescent psychiatric disorders during the COVID-19 pandemic and lockdown

Highlights•The COVID-19 pandemic and lockdown may have a negative impact on the mental health of adolescents. •Epidemics and disasters are associated with adolescent Post Traumatic Stress, Depression, and Anxiety symptoms. •Healthcare system adaptations are necessary for mental health support despite the lockdown. •Home confinement may be associated with increased intrafamilial violence. •Data is scarce on… Continue reading Adolescent psychiatric disorders during the COVID-19 pandemic and lockdown

Neuroticism, Worry, and Cardiometabolic Risk Trajectories: Findings From a 40‐Year Study of Men

Anxiety is linked to elevated risk of cardiometabolic disease onset, but the underlying mechanisms remain unclear. We examined the prospective association of 2 anxiety facets, neuroticism and worry, with cardiometabolic risk (CMR) trajectories for 4 decades. Methods and ResultsThe sample comprised 1561 men from an ongoing adult male cohort. In 1975, healthy men (mean age,… Continue reading Neuroticism, Worry, and Cardiometabolic Risk Trajectories: Findings From a 40‐Year Study of Men

The Lancet: COVID-19 pandemic led to stark rise in depressive and anxiety disorders globally in 2020, with women and younger people most affected

First global estimates of impact of the COVID-19 pandemic on mental health in 2020 suggests additional 53 million cases of major depressive disorder and 76 million cases of anxiety disorders were due to the pandemic.Women and younger people were the most affected by major depressive disorder and anxiety disorders in 2020.Countries hit hardest by the… Continue reading The Lancet: COVID-19 pandemic led to stark rise in depressive and anxiety disorders globally in 2020, with women and younger people most affected

On the relation of boredom and sadistic aggression.

What gives rise to sadism? While sadistic behavior (i.e., harming others for pleasure) is well-documented, past empirical research is nearly silent regarding the psychological factors behind it. We help close this gap by suggesting that boredom plays a crucial role in the emergence of sadistic tendencies. Across 9 diverse studies, we provide correlational and experimental… Continue reading On the relation of boredom and sadistic aggression.

A novel peripheral biomarker for depression and antidepressant response

In contrast to healthy controls, the heterotrimeric G protein, Gsalpha (Gsα) is ensconced predominantly in lipid rafts in subjects with major depressive disorder (MDD) resulting in impaired stimulation of adenylyl cyclase. In this small proof-of-concept study, we examined the hypothesis that translocation of Gsα from lipid rafts toward a more facile activation of adenylyl cyclase… Continue reading A novel peripheral biomarker for depression and antidepressant response

Loving-kindness meditation slows biological aging in novices: Evidence from a 12-week randomized controlled trial

Highlights•Over 12 weeks, loving-kindness meditation buffered telomere attrition. •Telomere length decreased in the mindfulness group and the control group. •The loving-kindness group showed less telomere attrition than the control group. AbstractCombinations of multiple meditation practices have been shown to reduce the attrition of telomeres, the protective caps of chromosomes (Carlson et al., 2015). Here, we… Continue reading Loving-kindness meditation slows biological aging in novices: Evidence from a 12-week randomized controlled trial