A EULAR taskforce was convened to develop recommendations for lifestyle behaviours in rheumatic and musculoskeletal diseases (RMDs). In this paper, the literature on the effect of diet on the progression of RMDs is reviewed. Methods Systematic reviews and meta-analyses were performed of studies related to diet and disease outcomes in seven RMDs: osteoarthritis (OA), rheumatoid… Continue reading Effects of diet on the outcomes of rheumatic and musculoskeletal diseases (RMDs): systematic review and meta-analyses informing the 2021 EULAR recommendations for lifestyle improvements in people with RMDs
Category: Orthopedy
Effect of Duloxetine on Opioid Use after Total Knee Arthroplasty. A Double-Blinded Randomized Control Trial
PosterDownload https://epostersonline.com/ASRASPRING21/node/1028
SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters
Extrapulmonary complications of different organ systems have been increasingly recognized in patients with severe or chronic Coronavirus Disease 2019 (COVID-19). However, limited information on the skeletal complications of COVID-19 is known, even though inflammatory diseases of the respiratory tract have been known to perturb bone metabolism and cause pathological bone loss. In this study, we… Continue reading SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters
Axial alignment is a critical regulator of knee osteoarthritis
Taking a load offOsteoarthritis (OA) is characterized by subchondral bone thickening in addition to cartilage degeneration. Here, Oláh et al. studied the role of joint alignment in OA development. Unloading the knee joint of a patient with OA with varus malalignment by high tibial osteotomy, which corrected axial malalignment, improved pain and cartilage microstructure and… Continue reading Axial alignment is a critical regulator of knee osteoarthritis
Association of Lithium Treatment With the Risk of Osteoporosis in Patients With Bipolar Disorder
Importance Osteoporosis, a systemic skeletal disorder associated with substantial morbidity and mortality, may be particularly common among individuals with bipolar disorder. Lithium, a first-line mood-stabilizing treatment for bipolar disorder, may have bone-protecting properties. Objective To evaluate if treatment with lithium is associated with a decrease in risk of osteoporosis among patients with bipolar disorder. Design,… Continue reading Association of Lithium Treatment With the Risk of Osteoporosis in Patients With Bipolar Disorder
Digit ratios and their asymmetries as risk factors of developmental instability and hospitalization for COVID-19
COVID-19 presents with mild symptoms in the majority of patients but in a minority it progresses to acute illness and hospitalization. Here we consider whether markers for prenatal sex hormones and postnatal stressors on developmental instability, i.e. digit ratios and their directional and unsigned asymmetries, are predictive of hospitalization. We focus on six ratios: 2D:3D;… Continue reading Digit ratios and their asymmetries as risk factors of developmental instability and hospitalization for COVID-19
Exercise-induced piezoelectric stimulation for cartilage regeneration in rabbits
Osteoarthritis is a common condition, but curative therapies are limited. Here, Liu and colleagues developed a biodegradable scaffold using PLLA [poly(L-lactic acid)] nanofibers that when placed under applied force generated a piezoelectric charge, leading to improved chondrogenesis in vitro. Rabbits with osteochondral defects in the medial femoral condyle that were treated with the PLLA scaffold… Continue reading Exercise-induced piezoelectric stimulation for cartilage regeneration in rabbits
Are biomechanics during gait associated with the structural disease onset and progression of lower limb osteoarthritis? A systematic review and meta-analysis
To evaluate if gait biomechanics are associated with increased risk of structurally diagnosed disease onset or progression of lower limb osteoarthritis (OA). MethodA systematic review of Medline and Embase was conducted from inception to July 2021. Two reviewers independently screened records, extracted data and assessed risk of bias. Included studies reported gait biomechanics at baseline,… Continue reading Are biomechanics during gait associated with the structural disease onset and progression of lower limb osteoarthritis? A systematic review and meta-analysis
Comparing Video-Based, Telehealth-Delivered Exercise and Weight Loss Programs With Online Education on Outcomes of Knee Osteoarthritis
Scalable knee osteoarthritis programs are needed to deliver recommended education, exercise, and weight loss interventions. Objective:To evaluate two 6-month, telehealth-delivered exercise programs, 1 with and 1 without dietary intervention. Design:3-group, parallel randomized (5:5:2) trial. (Australian New Zealand Clinical Trials Registry: ACTRN12618000930280) Setting:Australian private health insurance members. Participants:415 persons with symptomatic knee osteoarthritis and a body… Continue reading Comparing Video-Based, Telehealth-Delivered Exercise and Weight Loss Programs With Online Education on Outcomes of Knee Osteoarthritis
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