..Persons with arthritis have unique challenges because the interplay between anxiety, depression, and chronic pain is cyclical, with each having the potential to exacerbate the others. What is added by this report? In 2017, frequent mental distress and history of depression were commonly reported by adults with arthritis in all states, with clustering of high… Continue reading State-Specific Prevalence and Characteristics of Frequent Mental Distress and History of #Depression Diagnosis Among Adults with #Arthritis— United States, 2017
Category: Orthopedy
Efficacy and tolerability of #duloxetine in patients with knee #osteoarthritis: a meta‐analysis of randomised controlled trials
..Duloxetine achieved significant reductions in primary outcomes including Brief Pain Inventory 24‐h average pain score (weighted mean difference (WMD) = −0.74, 95% confidence interval (CI) = −0.92 to −0.57), weekly mean of the 24‐h average pain score (WMD = −0.76, 95% CI = −0.96 to −0.56), WOMAC stiffness score (WMD = −0.47, 95% CI =… Continue reading Efficacy and tolerability of #duloxetine in patients with knee #osteoarthritis: a meta‐analysis of randomised controlled trials
Influence of #sleep problems and co-occurring musculoskeletal pain on long-term prognosis of chronic low #backpain: the HUNT Study
Compared with persons without sleeplessness, persons who often/always experienced sleeplessness had a lower probability of recovery from chronic LBP (RR 0.65, 95% CI 0.57 to 0.74 in women and RR 0.81, 95% CI 0.69 to 0.95 in men). Although there was no clear evidence of statistical interaction between sleeplessness and co-occurring musculoskeletal pain, women and men who… Continue reading Influence of #sleep problems and co-occurring musculoskeletal pain on long-term prognosis of chronic low #backpain: the HUNT Study
Association between Dietary #Selenium Intake and the Prevalence of #Osteoporosis: A Cross-Sectional Study
To examine the correlation between dietary selenium (Se) intake and the prevalence of osteoporosis (OP) in the general middle-aged and older population in China ..Compared with the lowest quartile, the energy intake, age, gender and body mass index (BMI)-adjusted odds ratios of OP were 0.72 (95% confidence interval CI 0.55-0.94), 0.72 (95% CI 0.51-1.01) and… Continue reading Association between Dietary #Selenium Intake and the Prevalence of #Osteoporosis: A Cross-Sectional Study
Short #Sleep Is Associated With Low Bone Mineral Density and #Osteoporosis in the Women’s Health Initiative
.. In adjusted linear regression models, women who reported sleeping 5 hours or less per night had on average 0.012 to 0.018 g/cm2 significantly lower BMD at all four sites compared with women who reported sleeping 7 hours per night (reference). In adjusted multinomial models, women reporting 5 hours or less per night had higher odds of low bone… Continue reading Short #Sleep Is Associated With Low Bone Mineral Density and #Osteoporosis in the Women’s Health Initiative
#Atopic eczema and #fracture risk in adults: A population-based cohort study
..Those with eczema had increased risk of hip (HR, 1.10; 99% CI, 1.06-1.14), pelvic (HR, 1.10; 99% CI, 1.02-1.19), spinal (HR, 1.18; 99% CI, 1.10-1.27), and wrist (HR, 1.07; 99% CI, 1.03,-1.11) fractures. We found no evidence of increased proximal humeral (HR, 1.06; 99% CI, 0.97-1.15) fracture risk. Fracture risk increased with increasing eczema severity,… Continue reading #Atopic eczema and #fracture risk in adults: A population-based cohort study
Results of a 6-week treatment with 10 mg prednisolone in patients with hand #osteoarthritis (HOPE): a double-blind, randomised, placebo-controlled trial
..The mean change between baseline and week 6 on VAS-reported finger pain was −21·5 (SD 21·7) in the prednisolone group and −5·2 (24·3) in the placebo group, with a mean between-group difference (of prednisolone vs placebo) of −16·5 (95% CI −26·1 to −6·9; p=0·0007). The number of non-serious adverse events was similar between the groups.… Continue reading Results of a 6-week treatment with 10 mg prednisolone in patients with hand #osteoarthritis (HOPE): a double-blind, randomised, placebo-controlled trial
Diagnosis of #osteoporosis in #statin-treated patients is dose-dependent
..There was a highly non-trivial dependence of statin dosage with the ORs of osteoporosis. Osteoporosis was underrepresented in low-dose statin treatment (0–10 mg per day), including lovastatin (OR: 0.39, CI 0.18 to 0.84, p<0.05), pravastatin (OR: 0.68, 95% CI 0.52 to 0.89, p<0.01), simvastatin (OR: 0.70, 95% CI 0.56 to 0.86, p<0.01) and rosuvastatin (OR: 0.69, 95% CI 0.55… Continue reading Diagnosis of #osteoporosis in #statin-treated patients is dose-dependent
Cleveland Clinic Unveils Top 10 Medical #Innovations for 2020
1. Dual-Acting Osteoporosis Drug 2. Expanded Use of Minimally Invasive Mitral Valve Surgery 3. Inaugural Treatment for Transthyretin Amyloid Cardiomyopathy 4. Therapy for Peanut Allergies 5. Closed-Loop Spinal Cord Stimulation 6. Biologics in Orthopaedic Repair 7. Antibiotic Envelope for Cardiac Implantable Device Infection Prevention 8. Bempedoic Acid for Cholesterol Lowering in Statin Intolerant Patients 9.… Continue reading Cleveland Clinic Unveils Top 10 Medical #Innovations for 2020
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