Objective To investigate the associations between a comprehensive set of retinal vascular parameters and incident stroke to unveil new associations and explore its predictive power for stroke risk.Methods Retinal vascular parameters were extracted from the UK Biobank fundus images using the Retina-based Microvascular Health Assessment System. We used Cox regression analysis, adjusted for traditional risk… Continue reading #Retinal vascular fingerprints predict incident #stroke: findings from the UK Biobank cohort study
Category: Ophthalmology
High Density #Lipoproteins Associate with Age-Related #Macular Degeneration in the All of Us Research Program
OBJECTIVEExtracellular lipoprotein aggregation is a critical event in AMD pathogenesis. In this study, we sought to analyze associations between clinical and genetic-based factors related to lipoprotein metabolism and risk for age-related macular degeneration (AMD) in the All of Us research program.DESIGNCross-sectional retrospective data analysis.SUBJECTS5028 healthy and 2328 AMD patients from All of Us.METHODSParticipants with and… Continue reading High Density #Lipoproteins Associate with Age-Related #Macular Degeneration in the All of Us Research Program
Screening for advanced #liver fibrosis due to metabolic dysfunction-associated #steatotic liver disease alongside #retina scanning in people with type 2 diabetes: a cross-sectional study
BackgroundInternational guidelines suggest screening for advanced fibrosis due to metabolic dysfunction-associated steatotic liver disease in people with type 2 diabetes, but how to implement these guidelines in clinical care remains unclear. We hypothesise that examination with VCTE could be implemented simultaneously with retina scanning with a high acceptance rate in people with type 2 diabetes.… Continue reading Screening for advanced #liver fibrosis due to metabolic dysfunction-associated #steatotic liver disease alongside #retina scanning in people with type 2 diabetes: a cross-sectional study
#Empagliflozin and the Risk of #Retinopathy in Patients With Type 2 Diabetes
Question Is there an association between empagliflozin and the risk of nonproliferative diabetic retinopathy (NPDR) and diabetic retinopathy (DR) progression in patients with type 2 diabetes (T2D)?Findings In this cohort study, there was no association between empagliflozin and incident NPDR in patients with T2D who had no DR history; however, empagliflozin was associated with a… Continue reading #Empagliflozin and the Risk of #Retinopathy in Patients With Type 2 Diabetes
#Pistachio Consumption Increases #Macular Pigment #Optical Density in Healthy Adults: A Randomized Controlled Trial
BackgroundPistachios are a bioavailable source of the xanthophyll lutein. Along with zeaxanthin, these plant pigments are major components of macular pigment (MP) in the human retina. MP can be non-invasively measured and is referred to as MP optical density (MPOD). MPOD is modifiable with dietary interventions that include lutein and zeaxanthin (L/Z). Higher MPOD protects… Continue reading #Pistachio Consumption Increases #Macular Pigment #Optical Density in Healthy Adults: A Randomized Controlled Trial
#Vision Impairment and the Population Attributable Fraction of #Dementia in Older Adults
Importance Vision impairment is a potentially modifiable risk factor for dementia. Although few prior studies have estimated the contribution of vision impairments to dementia, none have reported on multiple objectively measured vision impairments (eg, distance and near visual acuity and contrast sensitivity) in a nationally representative sample of older adults.Objective To quantify population attributable fractions of dementia… Continue reading #Vision Impairment and the Population Attributable Fraction of #Dementia in Older Adults
#Vision Impairment and the Population Attributable Fraction of #Dementia in Older #Adults
Importance Vision impairment is a potentially modifiable risk factor for dementia. Although few prior studies have estimated the contribution of vision impairments to dementia, none have reported on multiple objectively measured vision impairments (eg, distance and near visual acuity and contrast sensitivity) in a nationally representative sample of older adults.Objective To quantify population attributable fractions of dementia… Continue reading #Vision Impairment and the Population Attributable Fraction of #Dementia in Older #Adults
#Choroidal and #retinal thinning in chronic #kidney disease independently associate with eGFR decline and are modifiable with treatment
In patients with chronic kidney disease (CKD), there is an unmet need for novel biomarkers that reliably track kidney injury, demonstrate treatment-response, and predict outcomes. Here, we investigate the potential of retinal optical coherence tomography (OCT) to achieve these ends in a series of prospective studies of patients with pre-dialysis CKD (including those with a… Continue reading #Choroidal and #retinal thinning in chronic #kidney disease independently associate with eGFR decline and are modifiable with treatment
Enhancing Vision: Exploring the Link Between Vitamin #C and Reduced #Cataract Risks – A Physician’s Perspective
As physicians continually explore avenues for promoting overall health, recent research has shed light on a potential ally in the fight against cataracts – Vitamin C. This essential nutrient, long celebrated for its immune-boosting properties, is now gaining recognition for its potential role in reducing the risk of cataract development. In this blog post, I… Continue reading Enhancing Vision: Exploring the Link Between Vitamin #C and Reduced #Cataract Risks – A Physician’s Perspective