BackgroundAllergic rhinitis (AR) is a widely diffused atopic disease that is hardly managed by conventional therapy, especially in the long-term. Fatty acids (FAs), which possess both anti-inflammatory and immunomodulatory properties, could be used to control AR symptoms.ObjectiveWe aimed at evaluating the benefits (efficacy in reducing symptoms and safety) of using an oral supplement containing FAs… Continue reading Multicentre, double-blind, randomized placebo-controlled trial to evaluate the therapeutic efficacy of #nutraceutical combination in the treatment of #allergic #rhinitis
Category: ENT
The clinical effectiveness of #clarithromycin versus endoscopic sinus surgery for adults with chronic #rhinosinusitis with and without nasal #polyps (MACRO): a pragmatic, multicentre, three-arm, randomised, placebo-controlled phase 4 trial
SummaryBackgroundA paucity of evidence regarding use of endoscopic sinus surgery and antibiotics in managing chronic rhinosinusitis has contributed to a five-times variation in endoscopic sinus surgery rates, as well as variation in the use of antibiotics. The main aim of the present trial was to compare the clinical effectiveness of endoscopic sinus surgery or 3… Continue reading The clinical effectiveness of #clarithromycin versus endoscopic sinus surgery for adults with chronic #rhinosinusitis with and without nasal #polyps (MACRO): a pragmatic, multicentre, three-arm, randomised, placebo-controlled phase 4 trial
#Echoes in the night: How #sleep quality influences #auditory health
Sleep disorders may lead to hearing loss.• Complex relationship between sleep quality, auditory sense and mental health.• Oxidative stress and immune response may be potential mechanisms.• Current treatment strategies are limited and separate. AbstractThe intricate relationship between sleep disorders and hearing loss emerges as a burgeoning field of scholarly inquiry. Numerous studies have illuminated a… Continue reading #Echoes in the night: How #sleep quality influences #auditory health
Association of 15 common dietary factors with #tinnitus: a systematic review and meta-analysis of observational studies
Objective A systematic analysis was conducted to investigate the association between tinnitus incidence and daily dietary patterns.Design We conducted a systematic review and meta-analysis of observational studies.Data sources The PubMed, Embase, Web of Science and Cochrane Library databases were searched from their inception to 25 May 2024.Eligibility criteria for selecting studies We included observational studies… Continue reading Association of 15 common dietary factors with #tinnitus: a systematic review and meta-analysis of observational studies
Posttraumatic #Stress Disorder and Obstructive Sleep #Apnea in Twins
Key PointsQuestion What is the association of posttraumatic stress disorder (PTSD) with obstructive sleep apnea (OSA) after accounting for acknowledged medical risk factors for OSA?Findings In a cross-sectional study of 132 older male veteran twins discordant for PTSD undergoing in-laboratory polysomnography, current PTSD diagnosis and symptoms were associated independently with OSA, even after controlling for demographics, behavioral… Continue reading Posttraumatic #Stress Disorder and Obstructive Sleep #Apnea in Twins
#Olfactory Impairment and the Risk of Major Adverse #Cardiovascular Outcomes in Older Adults
BackgroundOlfactory impairment is common in older adults and may be associated with adverse cardiovascular health; however, empirical evidence is sparse. We examined olfaction in relation to the risk of coronary heart disease (CHD), stroke, and congestive heart failure (CHF).Methods and ResultsThis study included 2537 older adults (aged 75.6±2.8 years) from the Health ABC (Health, Aging, and… Continue reading #Olfactory Impairment and the Risk of Major Adverse #Cardiovascular Outcomes in Older Adults
Association between #sinusitis and incident #rheumatic diseases: a population-based study
To determine whether antecedent sinusitis is associated with incident rheumatic disease.Methods This population-based case–control study included all individuals meeting classification criteria for rheumatic diseases between 1995 and 2014. We matched three controls to each case on age, sex and length of prior electronic health record history. The primary exposure was presence of sinusitis, ascertained by diagnosis… Continue reading Association between #sinusitis and incident #rheumatic diseases: a population-based study
Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial
Hearing loss is associated with increased cognitive decline and incident dementia in older adults. We aimed to investigate whether a hearing intervention could reduce cognitive decline in cognitively healthy older adults with hearing loss.MethodsThe ACHIEVE study is a multicentre, parallel-group, unmasked, randomised controlled trial of adults aged 70–84 years with untreated hearing loss and without… Continue reading Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial
Noninvasive Voice Biomarker Is Associated With Incident Coronary Artery Disease Events at Follow-up
AbstractObjectiveTo evaluate the association between a preidentified voice biomarker and incident coronary artery disease (CAD) events. MethodsPatients referred for clinically indicated coronary angiography underwent a total of three 30-second voice recordings using the Vocalis Health smartphone application between January 1, 2015, and February 28, 2017. A pre-established voice biomarker was derived from each individual recording,… Continue reading Noninvasive Voice Biomarker Is Associated With Incident Coronary Artery Disease Events at Follow-up
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