..Three insomnia symptoms were assessed with self-reported difficulties in initiating or maintaining sleep, early morning awakening, and daytime dysfunction for at least 3 d/wk at baseline ..Cox regressions showed that 3 insomnia symptoms were associated with increased risk of total #CVD, with respective adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) of 1.09 (95%… Continue reading #Insomnia symptoms and risk of cardiovascular diseases among 0.5 million adults. A 10-year cohort
Category: Cardiology
Is #running associated with a lower risk of all-cause, #cardiovascular and cancer #mortality, and is the more the better? A systematic review and meta-analysis
Fourteen studies from six prospective cohorts with a pooled sample of 232 149 participants were included. In total, 25 951 deaths were recorded during 5.5–35 year follow-ups. Our meta-analysis showed that running participation is associated with 27%, 30% and 23% lower risk of all-cause (pooled adjusted hazard ratio (HR)=0.73; 95% confidence interval (CI) 0.68 to 0.79), cardiovascular (HR=0.70;… Continue reading Is #running associated with a lower risk of all-cause, #cardiovascular and cancer #mortality, and is the more the better? A systematic review and meta-analysis
Does chronic high-intensity #endurance training have an effect on cardiovascular markers of active populations and athletes? Systematic review and meta-analysis
There was significant improvement in high-density #lipoprotein with weighted standardised mean difference and effect size=−1.06 (−1.83 to −0.30), p=0.006. We have also observed a significant reduction in low-density lipoprotein and total cholesterol with weighted standardised mean difference and effect size=−0.97 (−1.58 to −0.36), p=0.002, and = −0.78 (−1.34 to −0.22), p=0.007, respectively. There was a… Continue reading Does chronic high-intensity #endurance training have an effect on cardiovascular markers of active populations and athletes? Systematic review and meta-analysis
Relationship between #obesity indices and #hypertension among middle-aged and elderly populations in Taiwan: A community-based, cross-sectional study
..The obesity indices included body mass index (BMI), body fat (BF) percentage and waist circumference (WC). Of the 396 people recruited, 200 had HTN. The age-adjusted Pearson’s coefficients of BMI, BF percentage and WC were 0.23 (p<0.001), 0.14 (p=0.01) and 0.26 (p<0.001), respectively. Multiple logistic regression of the HTN-related obesity indices showed that the ORs… Continue reading Relationship between #obesity indices and #hypertension among middle-aged and elderly populations in Taiwan: A community-based, cross-sectional study
Association of #Obesity Phenotypes with Electrocardiographic Markers of Poor Outcomes in the General Population
This study aimed to investigate the association of metabolically healthy obesity (MHO) and other obesity phenotypes with electrocardiographic (#ECG) markers to understand the pathophysiological basis of increased cardiovascular disease (CVD) risk associated with these phenotypes metabolically healthy without obesity [MHNO; reference] Higher odds of prolonged PR interval, P‐wave duration, and QRS duration were observed among… Continue reading Association of #Obesity Phenotypes with Electrocardiographic Markers of Poor Outcomes in the General Population
Bilateral high-frequency hearing loss is associated with elevated blood #pressure and increased hypertension risk in occupational #noise exposed workers
..bilateral high-frequency hearing loss (BHFHL) Increasing years of occupational noise exposure and BHFHL were significantly associated with systolic and diastolic blood pressure increase (all P<0.001). The lineal trend was only significant in males, with adjusted ORs for hypertension gradually increasing with increasing years of occupational noise exposure (P<0.001). Furthermore, subjects having mild and high BHFHL… Continue reading Bilateral high-frequency hearing loss is associated with elevated blood #pressure and increased hypertension risk in occupational #noise exposed workers
Effect of hormone replacement therapy on #atherogenic lipid profile in postmenopausal women
..Recent studies suggest that hormone replacement therapy (#HRT) is cardioprotective when initiated early after menopause, but the mechanisms involved are still unclear. One-hundred and forty postmenopausal women <70 years were included in EVTET and randomized either to active treatment (one tablet of 2 mg estradiol and 1 mg norethisterone acetate daily) (n = 71) or placebo (n = 69). Our study show… Continue reading Effect of hormone replacement therapy on #atherogenic lipid profile in postmenopausal women
#Statins After Myocardial Infarction in the Oldest: A Cohort Study in the Clinical Practice Research Datalink Database
Among the 3900 patients aged 80 years and older, 2 years of statin prescriptions resulted in a lower risk of the composite outcome (adjusted HR = 0.81; 95% confidence interval [CI] = 0.66‐0.99) and of all‐cause mortality (adjusted HR = 0.84; 95% CI = 0.73‐0.97). During 4.5 years of median follow‐up, the NNT for prevention of the primary outcome… Continue reading #Statins After Myocardial Infarction in the Oldest: A Cohort Study in the Clinical Practice Research Datalink Database
Comprehensive comparative effectiveness and safety of first-line #antihypertensive drug classes: a systematic, multinational, large-scale analysis
..Most estimates revealed no effectiveness differences between classes; however, #thiazide or thiazide-like diuretics showed better primary effectiveness than angiotensin-converting enzyme inhibitors: acute myocardial infarction (HR 0·84, 95% CI 0·75–0·95), hospitalisation for heart failure (0·83, 0·74–0·95), and stroke (0·83, 0·74–0·95) risk while on initial treatment. Safety profiles also favoured thiazide or thiazide-like diuretics over angiotensin-converting enzyme… Continue reading Comprehensive comparative effectiveness and safety of first-line #antihypertensive drug classes: a systematic, multinational, large-scale analysis
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