The appropriate dose of aspirin to lower the risk of death, myocardial infarction, and stroke and to minimize major bleeding in patients with established atherosclerotic cardiovascular disease is a subject of controversy. METHODSUsing an open-label, pragmatic design, we randomly assigned patients with established atherosclerotic cardiovascular disease to a strategy of 81 mg or 325 mg… Continue reading Comparative Effectiveness of #Aspirin Dosing in #Cardiovascular Disease
Category: Cardiology
#Smoking is associated with impaired verbal learning and #memory performance in women more than men
Vascular contributions to cognitive impairment and dementia (VCID) include structural and functional blood vessel injuries linked to poor neurocognitive outcomes. Smoking might indirectly increase the likelihood of cognitive impairment by exacerbating vascular disease risks. Sex disparities in VCID have been reported, however, few studies have assessed the sex-specific relationships between smoking and memory performance and… Continue reading #Smoking is associated with impaired verbal learning and #memory performance in women more than men
Prospective Case-Control Study of #Cardiovascular Abnormalities 6 Months Following Mild #COVID-19 in Healthcare Workers
ObjectivesThe purpose of this study was to detect cardiovascular changes after mild severe acute respiratory syndrome coronavirus 2 infection.BackgroundConcern exists that mild coronavirus disease 2019 may cause myocardial and vascular disease. MethodsParticipants were recruited from COVIDsortium, a 3-hospital prospective study of 731 health care workers who underwent first-wave weekly symptom, polymerase chain reaction, and serology… Continue reading Prospective Case-Control Study of #Cardiovascular Abnormalities 6 Months Following Mild #COVID-19 in Healthcare Workers
#Cardiovascular symptoms affect the patterns of habitual #coffee consumption
Excessive coffee consumption can lead to unpleasant sensations such as tachycardia and heart palpitations. ObjectivesOur aim was to investigate if cardiovascular symptoms can lead to alterations in habitual patterns of coffee consumption. MethodsWe used information from up to 390,435 European ancestry participants in the UK Biobank, aged 39–73 y. Habitual coffee consumption was self-reported, and… Continue reading #Cardiovascular symptoms affect the patterns of habitual #coffee consumption
Genetic analysis in European ancestry individuals identifies 517 loci associated with #liver enzymes
Serum concentration of hepatic enzymes are linked to liver dysfunction, metabolic and cardiovascular diseases. We perform genetic analysis on serum levels of alanine transaminase (ALT), alkaline phosphatase (ALP) and gamma-glutamyl transferase (GGT) using data on 437,438 UK Biobank participants. Replication in 315,572 individuals from European descent from the Million Veteran Program, Rotterdam Study and Lifeline… Continue reading Genetic analysis in European ancestry individuals identifies 517 loci associated with #liver enzymes
Pharmacological blood #pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis
The effects of pharmacological blood pressure lowering at normal or high-normal blood pressure ranges in people with or without pre-existing cardiovascular disease remains uncertain. We analysed individual participant data from randomised trials to investigate the effects of blood pressure lowering treatment on the risk of major cardiovascular events by baseline levels of systolic blood pressure.… Continue reading Pharmacological blood #pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis
Initial Findings From the North American #COVID-19 Myocardial #Infarction Registry
The coronavirus disease 2019 (COVID-19) pandemic has impacted many aspects of ST-segment elevation myocardial infarction (STEMI) care, including timely access to primary percutaneous coronary intervention (PPCI). ObjectivesThe goal of the NACMI (North American COVID-19 and STEMI) registry is to describe demographic characteristics, management strategies, and outcomes of COVID-19 patients with STEMI. MethodsA prospective, ongoing observational… Continue reading Initial Findings From the North American #COVID-19 Myocardial #Infarction Registry
Long-term body mass index changes in #overweight and #obese adults and the risk of heart failure, #cardiovascular disease and mortality: a cohort study of over 260,000 adults in the UK
Although obesity is a well-recognised risk factor for cardiovascular disease (CVD), the impact of long-term body mass index (BMI) changes in overweight or obese adults, on the risk of heart failure, CVD and mortality has not been quantified. MethodsThis population-based cohort study used routine UK primary care electronic health data linked to secondary care and… Continue reading Long-term body mass index changes in #overweight and #obese adults and the risk of heart failure, #cardiovascular disease and mortality: a cohort study of over 260,000 adults in the UK
Exploring Posttraumatic #Stress Disorder as a #Cardiovascular Risk Factor in Women VeteransThe Heart of the Matter
The connection between emotional and physical health has long been recognized, with a great deal of research focusing on the risk of cardiovascular disease (CVD). The landmark INTERHEART study1 of nearly 30 000 people from 52 countries found that psychosocial factors, including depression and stressful life events, accounted for approximately one-third of the population-attributable risk of… Continue reading Exploring Posttraumatic #Stress Disorder as a #Cardiovascular Risk Factor in Women VeteransThe Heart of the Matter
2 Medical News 