Purpose It is recognized that disruptions in circadian behavior, such as with shift work or jet lag, are associated with diminished health. This known relationship implies that people with stronger indices of circadian behavior will exhibit improved physiology. To address the association between rhythmic activity behavior and physiology we proposed that metrics indicative of ‘more… Continue reading Rest #Activity Rhythms and their Association with #Cardiorespiratory Fitness and #Walking Energetics in #Older Adults: Study of Muscle, #Mobility and #Aging
Category: Aging
Vitamin #D3 and marine ω-3 fatty acids supplementation and leukocyte #telomere length: 4-year findings from the VITamin D and OmegA-3 TriaL (VITAL) randomized controlled trial
Limited studies suggest that vitamin D or omega 3 fatty acids (n–3 FAs) supplementation may be beneficial for telomere maintenance; however, evidence from large randomized clinical trials is lacking. We hypothesized that vitamin D or n–3 FAs supplementation reduce leukocyte telomere length (LTL) attrition over time by leveraging the VITamin D and OmegA-3 TriaL (VITAL)… Continue reading Vitamin #D3 and marine ω-3 fatty acids supplementation and leukocyte #telomere length: 4-year findings from the VITamin D and OmegA-3 TriaL (VITAL) randomized controlled trial
Dietary #Carbohydrate Intake, Carbohydrate Quality, and Healthy #Aging in Women
Importance Dietary carbohydrate quality is inversely associated with risks of chronic disease and all-cause mortality. However, limited evidence exists regarding the role of carbohydrate quality and dietary carbohydrate types in promoting healthy aging.Objective To evaluate the long-term role of dietary carbohydrate intake and carbohydrate quality in healthy aging.Design, Setting, and Participants This prospective cohort study… Continue reading Dietary #Carbohydrate Intake, Carbohydrate Quality, and Healthy #Aging in Women
Cumulative associations between #health behaviours, mental well-being, and health over 30 years
BackgroundBoth the number of risky health behaviours and the duration of exposure to these behaviours over time may increase the risk of later adverse outcomes. This study examined cumulative associations of risky health behaviours with both positive and negative aspects of mental well-being and health. It has a uniquely long follow-up period of over 30 years,… Continue reading Cumulative associations between #health behaviours, mental well-being, and health over 30 years
Systemic deficits in lipid homeostasis promote aging-associated impairments in #B cell progenitor development
Organismal aging has been associated with diverse metabolic and functional changes across tissues. Within the immune system, key features of physiological hematopoietic cell aging include increased fat deposition in the bone marrow, impaired hematopoietic stem and progenitor cell (HSPC) function, and a propensity towards myeloid differentiation. This shift in lineage bias can lead to pre-malignant… Continue reading Systemic deficits in lipid homeostasis promote aging-associated impairments in #B cell progenitor development
60 is the new 40: preparing for better bone #health in later life
Objective: In this study we evaluated associations between nutritional factors, including calcium supplementation, and outcomes of fracture and cardiovascular mortality. We chose to report both outcomes as an illustration of the importance of nutritional factors in midlife to heart disease as this may be more impactful for supporting behavior change strategies, particularly in men.Methods: This… Continue reading 60 is the new 40: preparing for better bone #health in later life
Optimal #dietary patterns for healthy #aging
As the global population ages, it is critical to identify diets that, beyond preventing noncommunicable diseases, optimally promote healthy aging. Here, using longitudinal questionnaire data from the Nurses’ Health Study (1986–2016) and the Health Professionals Follow-Up Study (1986–2016), we examined the association of long-term adherence to eight dietary patterns and ultraprocessed food consumption with healthy… Continue reading Optimal #dietary patterns for healthy #aging
Association of #Diet and #Waist-to-Hip Ratio With Brain Connectivity and #Memory in #Aging
Importance Epidemiological studies suggest that lifestyle factors are associated with risk of dementia. However, few studies have examined the association of diet and waist to hip ratio (WHR) with hippocampus connectivity and cognitive health.Objective To ascertain how longitudinal changes in diet quality and WHR during midlife are associated with hippocampal connectivity and cognitive function in… Continue reading Association of #Diet and #Waist-to-Hip Ratio With Brain Connectivity and #Memory in #Aging
Suboptimal #dietary patterns are associated with accelerated biological #aging in young adulthood: A study with twins
Background & aimsSuboptimal diets increase morbidity and mortality risk. Epigenetic clocks are algorithms that can assess health and lifespan, even at a young age, before clinical manifestations of diseases. We investigated the association between dietary patterns and biological aging in young adult twins.MethodsThe data were drawn from the population-based FinnTwin12 study and consisted of twins… Continue reading Suboptimal #dietary patterns are associated with accelerated biological #aging in young adulthood: A study with twins
