Background/objective: The relationship between frailty and sarcopenia is well-known in older adults, but the factors associated with frailty were not adequately investigated. This study aimed to investigate the relationship between frailty levels and balance, fall risk, and kinesiophobia in older adults with primary sarcopenia and to compare them by sex.Methods: This cross-sectional study included 68… Continue reading Impact of #frailty on balance, fall risk, and kinesiophobia in #sarcopenic elderly
Category: Aging
Associations of #Wearable- Measured #Sleep and #Physical Activity With #Memory Performance in Older Adults: Cross-Sectional Study With Actigraphy and MRI
Background: Cognitive decline is a common aspect of aging, and identifying modifiable lifestyle factors-such as physical activity and sleep-are crucial for promoting healthy brain aging. While both are individually linked to cognition, few studies have simultaneously assessed their independent and combined effects using objective wearable-based data, particularly in older Asian populations.Objective: This study aimed to… Continue reading Associations of #Wearable- Measured #Sleep and #Physical Activity With #Memory Performance in Older Adults: Cross-Sectional Study With Actigraphy and MRI
Real-World #Edoxaban Concentrations in #Older Patients Receiving Reduced-Dose Regimens
This study investigated real-world edoxaban concentrations across different dosing regimens, with a specific focus on patients who met the inclusion criteria of low-dose edoxaban for the Elder Care Atrial Fibrillation (ELDERCARE-AF) trial. Patients with atrial fibrillation receiving edoxaban were enrolled to measure trough concentrations. The levels were compared with the expected therapeutic range (12–43 ng/mL) to… Continue reading Real-World #Edoxaban Concentrations in #Older Patients Receiving Reduced-Dose Regimens
Relative associations of #coffee, #tea, and plain #water with all-cause and cause-specific #mortality: a prospective cohort study
Previous studies have highlighted the health benefits of coffee and tea, but they only focused on the comparisons between different consumptions. Consequently, the association estimate lacked a clear interpretation, as the substitution of beverages and distribution of doses were not explicitly prescribed. We focused on the “relative association” to ascertain the optimal consumption strategy (including… Continue reading Relative associations of #coffee, #tea, and plain #water with all-cause and cause-specific #mortality: a prospective cohort study
Effects of 2-year #cocoa extract# supplementation on #inflammaging biomarkers in older US adults: findings from the COcoa Supplement and Multivitamin Outcomes Study randomised clinical trial Get access Arrow
ObjectiveTo examine the long-term effect of cocoa flavanols on inflammaging biomarkers in the COcoa Supplement and Multivitamin Outcomes Study (COSMOS).MethodsCOSMOS is a large, randomised, double-blind, placebo-controlled, 2 × 2 factorial trial testing the effects of a cocoa extract supplement (containing 500 mg cocoa flavanols/day, including 80 mg (−)-epicatechin) among women aged ≥65 years and men aged ≥60… Continue reading Effects of 2-year #cocoa extract# supplementation on #inflammaging biomarkers in older US adults: findings from the COcoa Supplement and Multivitamin Outcomes Study randomised clinical trial Get access Arrow
#Meal timing trajectories in #older adults and their associations with #morbidity, genetic profiles, and #mortality
Older adults are vulnerable to mistimed food intake due to health and environmental changes; characterizing meal timing may inform strategies to promote healthy aging. We investigated longitudinal trajectories of self-reported meal timing in older adults and their associations with morbidity, genetic profiles, and all-cause mortality.MethodsWe analyzed data from 2945 community-dwelling older adults from the University… Continue reading #Meal timing trajectories in #older adults and their associations with #morbidity, genetic profiles, and #mortality
The declining #mental #health of the #young and the global disappearance of the #unhappiness hump shape in #age
Across many studies subjective well-being has followed a U-shape in age, declining until people reach middle-age, only to rebound subsequently. Ill-being has followed a mirror-imaged hump-shape. Using graphical and regression analyses of repeat cross-sectional micro-data from the United States and the United Kingdom, we show this empirical regularity has been replaced by a monotonic decrease… Continue reading The declining #mental #health of the #young and the global disappearance of the #unhappiness hump shape in #age
#Dietary patterns and accelerated multimorbidity in #older adults
Diet could influence disease development and shape multimorbidity trajectories. Here we examined how four dietary patterns relate to 15-year multimorbidity accumulation in 2,473 community-dwelling older adults from the Swedish SNAC-K cohort. Multimorbidity was operationalized as the total number of chronic conditions and grouped into three organ systems. Higher adherence to the Mediterranean-DASH Diet Intervention for… Continue reading #Dietary patterns and accelerated multimorbidity in #older adults
Association of #Egg Intake With #Alzheimer’s #Dementia Risk in #Older Adults: The Rush #Memory and Aging Project
BackgroundAlzheimer’s disease (AD) is a neurodegenerative disorder with increasing prevalence due to population aging. Eggs provide many nutrients important for brain health, including choline, omega-3 fatty acids, and lutein. Emerging evidence suggests that frequent egg consumption may improve cognitive performance on verbal tests, but whether consumption influences the risk of Alzheimer’s dementia and AD is… Continue reading Association of #Egg Intake With #Alzheimer’s #Dementia Risk in #Older Adults: The Rush #Memory and Aging Project
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