Background: Patients with fibromyalgia often experience repetitive negative thinking, which contributes to psychological distress. The Perseverative Thinking Questionnaire (PTQ) is a tool designed to assess this cognitive pattern. However, its psychometric properties have not been tested in fibromyalgia.Objective: This study aimed to assess the validity and reliability of the PTQ in patients with fibromyalgia.Methods: A… Continue reading Validity and reliability of the perseverative #thinking questionnaire in patients with #fibromyalgia
Author: aledopress
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Impact of #frailty on balance, fall risk, and kinesiophobia in #sarcopenic elderly
Background/objective: The relationship between frailty and sarcopenia is well-known in older adults, but the factors associated with frailty were not adequately investigated. This study aimed to investigate the relationship between frailty levels and balance, fall risk, and kinesiophobia in older adults with primary sarcopenia and to compare them by sex.Methods: This cross-sectional study included 68… Continue reading Impact of #frailty on balance, fall risk, and kinesiophobia in #sarcopenic elderly
Effects of #finerenone on arterial stiffness and cardiorenal biomarkers in patients with type 2 #diabetes and chronic #kidney disease: a randomised placebo-controlled mechanistic trial (FIVE-STAR)
Background: The mechanisms underlying cardiorenal benefits of finerenone remain unclear. This mechanistic trial aimed to evaluate the effects of finerenone on vascular stiffness, as assessed using the cardio-ankle vascular index (CAVI), and cardiorenal biomarkers in patients with type 2 diabetes (T2D) and chronic kidney disease (CKD).Methods: Eligible patients with T2D and CKD (estimated glomerular filtration… Continue reading Effects of #finerenone on arterial stiffness and cardiorenal biomarkers in patients with type 2 #diabetes and chronic #kidney disease: a randomised placebo-controlled mechanistic trial (FIVE-STAR)
Transition between #prediabetic and #diabetic stages in an urban community in india: a decade-long retrospective cohort study
The rising prevalence of prediabetes has increased the risk of diabetes, particularly among younger populations, if timely interventions are not implemented. In India, the limited availability of cohort-based incidence studies underscores the need for retrospective analyses using hospital-based electronic medical information systems (EMIS). This study estimates the transition probabilities and duration of stay in the… Continue reading Transition between #prediabetic and #diabetic stages in an urban community in india: a decade-long retrospective cohort study
#Ultra-processed foods and human health: the main thesis and the evidence
This first paper in a three-part Lancet Series combines narrative and systematic reviews with original analyses and meta-analyses to assess three hypotheses concerning a dietary pattern based on ultra-processed foods. The first hypothesis—that this pattern is globally displacing long-established diets centred on whole foods and their culinary preparation as dishes and meals—is supported by decades… Continue reading #Ultra-processed foods and human health: the main thesis and the evidence
A six-year longitudinal study identifies a #statin -independent association between low LDL- #cholesterol and risk of type 2 #diabetes
Statin therapy has been associated with increased risk of type 2 diabetes (T2D). We investigated the relationship between Low-Density Lipoprotein Cholesterol (LDL-C) plasma concentrations and incident T2D and evaluated the modifying effect of statin therapy in a large population-based cohort.MethodsIndividuals free of T2D and cardiovascular disease at baseline were followed longitudinally for the development of… Continue reading A six-year longitudinal study identifies a #statin -independent association between low LDL- #cholesterol and risk of type 2 #diabetes
#Electroacupuncture modulates myocardial insulin signaling and inflammatory markers in a rat model of type 2 #diabetes
Objective: To evaluate the effects of electroacupuncture (EA) on myocardial insulin resistance (IR) in Zucker diabetic fatty (ZDF) rats, an established model for type 2 diabetes mellitus (T2DM).Methods: Twenty-four ZDF-Leprfa/fa rats were randomized to: (1) ZDF group (n = 8); (2) ZDF + PIO (pioglitazone) group (n = 8); and (3) ZDF + EA group… Continue reading #Electroacupuncture modulates myocardial insulin signaling and inflammatory markers in a rat model of type 2 #diabetes
Alcohol’s Effects on the Lung and Lung Disease
Purpose: Alcohol misuse is widely accepted as an independent risk factor for a wide variety of lung diseases, such as pneumonia and acute respiratory distress syndrome. Alcohol induces changes in the regulatory mechanisms of the lung, both at a mechanical and immunological level. Understanding these changes might help discover new targets for drugs and therapeutic… Continue reading Alcohol’s Effects on the Lung and Lung Disease
Saline and #N-acetylcysteine based strategies and other approaches to prevent the risk of CA- #AKI: a meta-analysis
AbstractBackground: While hydration is currently the most evidence-supported strategy for preventing contrast-associated acute kidney injury (CA-AKI) in patients undergoing cardiovascular angiography, the potential benefits of combining a saline and N-acetylcysteine (NAC) based strategy with additional pharmacologic interventions remain uncertain.Methods: We conducted a search for randomized controlled trials (RCTs) in PubMed, Embase, and the Cochrane library… Continue reading Saline and #N-acetylcysteine based strategies and other approaches to prevent the risk of CA- #AKI: a meta-analysis
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