People receiving their first opioid prescription were propensity matched to people receiving NSAIDS (and, in sensitivity analysis, gabapentinoids) and the risk of death and hospitalization were compared, classifying opioid medication exposure as time-varying daily oral morphine milligram equivalents (MMEs) across time-varying eGFR. Prescriptions for 1–59 and ≥60 MMEs were associated with higher risk of death… Continue reading Associations of #Opioid Prescriptions with Death and Hospitalization across the Spectrum of Estimated #GFR
Author: aledopress
Risk of #rhabdomyolysis with #donepezil compared with rivastigmine or galantamine: a population-based cohort study
Donepezil, rivastigmine and galantamine are popular cholinesterase inhibitors used to manage the symptoms of #Alzheimer disease and other dementias; regulatory agencies in several countries warn about a possible risk of rhabdomyolysis.. ..The average age in our 2 groups was 81.1 years, and 61.4% of our population was female. Donepezil was associated with a higher risk… Continue reading Risk of #rhabdomyolysis with #donepezil compared with rivastigmine or galantamine: a population-based cohort study
Association of Use of Oral #Contraceptives With #Depressive Symptoms Among #Adolescents and Young Women
.. adolescent users (mean [SD] age, 16.5 [0.7] years) reported higher depressive symptom scores compared with their nonusing counterparts (mean [SD] age, 16.1 [0.6] years) (mean [SD] score, 0.40 [0.30] vs 0.33 [0.30]), which persisted after adjustment for age, socioeconomic status and ethnicity (β coefficient for interaction with age, –0.021; 95% CI, –0.038 to –0.005;… Continue reading Association of Use of Oral #Contraceptives With #Depressive Symptoms Among #Adolescents and Young Women
Childhood Tobacco Smoke Exposure and Risk of Atrial #Fibrillation in Adulthood
Of 2,816 Offspring cohort participants with at least 1 parent in the Original cohort, 82% were exposed to parental smoking. For every pack/day increase in parental smoking, there was an 18% increase in offspring AF incidence (adjusted hazard ratio [HR]: 1.18; 95% confidence interval [CI]: 1.00 to 1.39; p = 0.04). Additionally, parental smoking was… Continue reading Childhood Tobacco Smoke Exposure and Risk of Atrial #Fibrillation in Adulthood
Association of Attention-Deficit/Hyperactivity Disorder With Teenage Birth Among Women and Girls in Sweden
Teenage deliveries were more common among women and girls with #ADHD than among women and girls without ADHD (15.3% vs 2.8%; odds ratio [OR], 6.23 [95% CI, 5.80-6.68]). Compared with women and girls without ADHD, those with ADHD were more likely to present with risk factors for adverse obstetric and perinatal outcomes, including smoking during… Continue reading Association of Attention-Deficit/Hyperactivity Disorder With Teenage Birth Among Women and Girls in Sweden
Associations Between Time Spent Using Social Media and Internalizing and Externalizing Problems Among US Youth
In adjusted analyses, use of social media for more than 3 hours per day compared with no use remained significantly associated with internalizing problems alone (>3 to ≤6 hours: RRR, 1.60; 95% CI, 1.11-2.31; >6 hours: RRR, 1.78; 95% CI, 1.15-2.77) and comorbid internalizing and externalizing problems (>3 to ≤6 hours: RRR, 2.01; 95% CI,… Continue reading Associations Between Time Spent Using Social Media and Internalizing and Externalizing Problems Among US Youth
Risks of ischaemic heart disease and stroke in meat eaters, fish eaters, and vegetarians over 18 years of follow-up: results from the prospective EPIC-Oxford study
This difference was equivalent to 10 fewer cases of ischaemic heart disease (95% confidence interval 6.7 to 13.1 fewer) in vegetarians than in meat eaters per 1000 population over 10 years. The associations for ischaemic heart disease were partly attenuated after adjustment for self reported high blood cholesterol, high blood pressure, diabetes, and body mass… Continue reading Risks of ischaemic heart disease and stroke in meat eaters, fish eaters, and vegetarians over 18 years of follow-up: results from the prospective EPIC-Oxford study
Foreword
Buongiorno! Guten Tag! Good Morning! My name is Aldo, I am a physician and I live in Milano, Italy. I have always read a lot of medical news, and I have realised how difficult it is to forget to read those news if you’re not disciplined enough or if you don’t make that a habit. So I have decided to help myself and the community, here and on the Telegram app, and share just two articles daily, those that get my attention. All the articles can be searched by Category or Tag. Buona Lettura!
Population Impact Attributable to Modifiable Risk Factors for Hyperuricemia
BMI, alcohol intake, adherence to a DASH‐style diet, and diuretic use were all associated with serum urate levels and the presence of hyperuricemia in a dose‐response manner. The corresponding PARs of hyperuricemia cases for overweight/obesity (prevalence, 60%), non‐adherence to a DASH‐style diet (prevalence, 82%), alcohol use (prevalence, 48%), and diuretic use (prevalence, 8%) were 44%… Continue reading Population Impact Attributable to Modifiable Risk Factors for Hyperuricemia