..For older people, a long stay in the emergency department (ED) may reflect the complexity of their presentation, or deficiencies in systems that manage these complexities. ..Of 16 791 ED presentations made by older people, 4192 experienced a LLoS; 55% were admitted. Increasing age was associated with an increasing ED LoS. Factors most predictive of LLoS… Continue reading Predictors of a long length of stay in the emergency department for older people
Author: aledopress
Medicine and Technology enthusiast..
#Hydroxychloroquine or #chloroquine with or without a macrolide for treatment of #COVID-19: a multinational registry analysis
Hydroxychloroquine or chloroquine, often in combination with a second-generation macrolide, are being widely used for treatment of COVID-19, despite no conclusive evidence of their benefit. Although generally safe when used for approved indications such as autoimmune disease or malaria, the safety and benefit of these treatment regimens are poorly evaluated in COVID-19.. ..96 032 patients (mean… Continue reading #Hydroxychloroquine or #chloroquine with or without a macrolide for treatment of #COVID-19: a multinational registry analysis
Reducing #antibiotic prescribing and addressing the global problem of antibiotic resistance by targeted hygiene in the home and everyday life settings: A position paper
Highlights •Global & national AMR actions focus on infection prevention in healthcare settings. •Home & everyday life settings contribute to acquiring & spreading AMR pathogens. •Targeted hygiene protects against infections, reducing antibiotic prescribing. • Targeted hygiene helps to minimize selection pressure for AMR development globally. •Reducing AMR requires greater focus on targeted hygiene in the… Continue reading Reducing #antibiotic prescribing and addressing the global problem of antibiotic resistance by targeted hygiene in the home and everyday life settings: A position paper
#Remdesivir for the Treatment of #Covid-19 — Preliminary Report
..We conducted a double-blind, randomized, placebo-controlled trial of intravenous remdesivir in adults hospitalized with Covid-19 with evidence of lower respiratory tract involvement. Patients were randomly assigned to receive either remdesivir (200 mg loading dose on day 1, followed by 100 mg daily for up to 9 additional days) or placebo for up to 10 days.… Continue reading #Remdesivir for the Treatment of #Covid-19 — Preliminary Report
Assessment of a Prediction Model for Antidepressant Treatment Stability Using Supervised Topic Models
..Stable treatment response, intended as a proxy for treatment effectiveness, defined as continued prescription of an antidepressant for 90 days. Supervised topic models were used to extract 10 interpretable covariates from coded clinical data for stability prediction. With use of data from 1 hospital system (site A), generalized linear models and ensembles of decision trees… Continue reading Assessment of a Prediction Model for Antidepressant Treatment Stability Using Supervised Topic Models
#Hypocalcaemia predicts 12‐month re‐hospitalization in heart #failure
Potential pathophysiology of heart failure with preserved ejection fraction (HFpEF) has not been fully explored. The aim of the study was to reveal the association of serum calcium concentration at baseline with 12‐month clinical outcome in the disease.. ..Multivariate COX regression analysis revealed that baseline hypocalcaemia was associated with the increased risk of cardiac re‐hospitalization… Continue reading #Hypocalcaemia predicts 12‐month re‐hospitalization in heart #failure
Physical presence of spouse enhances brain-to-brain synchrony in co-parenting couples
Co-parenting spouses who live together remain in close physical proximity to each other and regularly engage in reciprocal social interactions in joint endeavors to coordinate their caregiving. Although bi-parental rearing is a common occurrence in humans, the influence of the physical presence of a co-parenting spouse on parental brain responses remains largely unknown. Synchrony is… Continue reading Physical presence of spouse enhances brain-to-brain synchrony in co-parenting couples
Outcomes of COVID-19 in 79 patients with #IBD in Italy: an IG-IBD study
COVID-19 has rapidly become a major health emergency worldwide. Patients with IBD are at increased risk of infection, especially when they have active disease and are taking immunosuppressive therapy. The characteristics and outcomes of COVID-19 in patients with IBD remain unclear.. ..Between 11 and 29 March 2020, 79 patients with IBD with COVID-19 were enrolled… Continue reading Outcomes of COVID-19 in 79 patients with #IBD in Italy: an IG-IBD study
Effects of #yoga on depressive symptoms in people with mental disorders: a systematic review and meta-analysis
..Eligibility criteria for selecting studies We included randomised controlled trials with a yoga intervention comprising ≥50% physical activity in adults with a recognised diagnosed mental disorder according to DSM-3, 4 or 5. Results 19 studies were included in the review (1080 participants) and 13 studies were included in the meta-analysis (632 participants). Disorders of depression,… Continue reading Effects of #yoga on depressive symptoms in people with mental disorders: a systematic review and meta-analysis
