Serial #sarcomere number is substantially decreased within the paretic #biceps brachii in individuals with chronic hemiparetic #stroke

A muscle’s structure, or architecture, is indicative of its function and is plastic; changes in input to or use of the muscle alter its architecture. Stroke-induced neural deficits substantially alter both input to and usage of individual muscles. We combined in vivo imaging methods (second-harmonic generation microendoscopy, extended field-of-view ultrasound, and fat-suppression MRI) to quantify… Continue reading Serial #sarcomere number is substantially decreased within the paretic #biceps brachii in individuals with chronic hemiparetic #stroke

A Systematic Review of Dietary #Supplements and Alternative Therapies for #Weight Loss

Dietary supplements and alternative therapies are commercialized as a panacea for obesity/weight gain as a result of the minimal regulatory requirements in demonstrating efficacy. These products may indirectly undermine the value of guideline-driven obesity treatments. Included in this study is a systematic review of the literature of purported dietary supplements and alternative therapies for weight… Continue reading A Systematic Review of Dietary #Supplements and Alternative Therapies for #Weight Loss

#Fibrosis improvement in patients with #HCV treated with direct-acting antivirals

More prospective studies are needed to characterize fibrosis improvement in patients with hepatitis C virus (HCV) who are treated with direct-acting antivirals (DAAs). The aims of this study were to assess changes in elastography scores from baseline to 1-year follow-up in patients with HCV, to identify factors that were independently associated with improvement in fibrosis… Continue reading #Fibrosis improvement in patients with #HCV treated with direct-acting antivirals

Common #dandelion (Taraxacum officinale) efficiently blocks the interaction between ACE2 cell surface receptor and #SARS-CoV-2 spike protein D614, mutants D614G, N501Y, K417N and E484K in vitro

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive. On 11th March 2020, coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, was declared as a global pandemic by the World Health Organization (WHO). To date, there… Continue reading Common #dandelion (Taraxacum officinale) efficiently blocks the interaction between ACE2 cell surface receptor and #SARS-CoV-2 spike protein D614, mutants D614G, N501Y, K417N and E484K in vitro

#Statin liver safety in non-alcoholic fatty #liver disease. A systematic review and metanalysis

Statin liver safety in non-alcoholic fatty liver disease (NAFLD) patients is not well defined. We analysed differences in liver function tests, including alanine transaminase aminotransferase (ALT), aspartate transaminase (AST), and gamma-glutamyl transpeptidase (GGT) in NAFLD patients treated or not with statins. MethodsWe performed a systematic review of MEDLINE via PubMed and EMBASE databases and metanalysis… Continue reading #Statin liver safety in non-alcoholic fatty #liver disease. A systematic review and metanalysis

Acute and long-term disruption of #glycometabolic control after #SARS-CoV-2 infection

Patients with coronavirus disease 2019 (COVID-19) are reported to have a greater prevalence of hyperglycaemia. Cytokine release as a consequence of severe acute respiratory syndrome coronavirus 2 infection may precipitate the onset of metabolic alterations by affecting glucose homeostasis. Here we describe abnormalities in glycometabolic control, insulin resistance and beta cell function in patients with… Continue reading Acute and long-term disruption of #glycometabolic control after #SARS-CoV-2 infection

Flourishing Despite #Migraines: A Nationally Representative Portrait of Resilience and Mental Health among Canadians

1) To examine the relationship between migraine status and complete mental health (CMH) among a nationally representative sample of Canadians; 2) To identify significant correlates of CMH among those with migraine. Methods Secondary analysis of the nationally representative Canadian Community Health Survey – Mental Health (CCHS-MH) (N=21,108). Bivariate analyses and a series of logistic regression… Continue reading Flourishing Despite #Migraines: A Nationally Representative Portrait of Resilience and Mental Health among Canadians

#Perception of invisible masked objects in early infancy

Recurrent loops in the visual cortex play a critical role in visual perception, which is likely not mediated by purely feed-forward pathways. However, the development of recurrent loops is poorly understood. The role of recurrent processing has been studied using visual backward masking, a perceptual phenomenon in which a visual stimulus is rendered invisible by… Continue reading #Perception of invisible masked objects in early infancy

Meta-Analysis of the Relationship between Abdominal #Obesity and Diabetic #Kidney Disease in Type 2 #Diabetic Patients

The meta-analysis aimed to investigate the association of visceral fat area (VFA), waist circumference (WC), waist-hip ratio (WHR) and waist-height ratio (WHtR) with diabetic kidney disease (DKD) in type 2 diabetic patients. Methods: Included studies were searched from Pubmed, Embase, and the Cochrane Library before July 2020. We synthesized the pooled results of the above… Continue reading Meta-Analysis of the Relationship between Abdominal #Obesity and Diabetic #Kidney Disease in Type 2 #Diabetic Patients