Aims: We evaluated the impact of scenario-based multifactorial control on the 3-year incidence of fatal/non-fatal cardiovascular disease (#CVD ) and associated healthcare costs in Asian patients with type 2 diabetes (#T2D ).Materials and methods: We applied the validated 'ABC' model to simulate the 3-year impact of attaining multiple treatment targets (HbA1c < 7%, blood pressure… Continue reading Impact of Simulated Risk Factor Management on Cardiovascular Disease and Costs in Type 2 Diabetes Using the ABC Model
Category: Cardiology
Blood Pressure Control and Mortality Among US Veterans
Background: Intensive blood #pressure (#BP) control reduces mortality and cardiovascular disease in clinical trials. However, real-world BP measurements often differ from standardized protocols. We evaluated the impact of real-world systolic BP on mortality among US Veterans.Methods: We conducted a retrospective cohort study of Veterans with hypertension, defined by diagnostic codes, antihypertensive prescriptions, or ≥2 office… Continue reading Blood Pressure Control and Mortality Among US Veterans
Skeletal and cardiac muscle longitudinal associations in the Baltimore Longitudinal Study of Aging (BLSA)
Background: #Sarcopenia, the age-related loss of skeletal muscle mass and function, has been linked to adverse health outcomes. Cross-sectional associations have been observed between skeletal and cardiac muscle mass and function in healthy, community-dwelling older adults during normative aging. Further longitudinal studies on the skeletal muscle-cardiac axis during aging are needed to inform the temporal… Continue reading Skeletal and cardiac muscle longitudinal associations in the Baltimore Longitudinal Study of Aging (BLSA)
Ethanol Infusion of the Vein of Marshall-Based Strategies for Persistent Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Trials
Background and aims: Pulmonary vein isolation (PVI) alone achieves modest arrhythmia freedom in persistent atrial #fibrillation (PeAF). Ethanol infusion of the vein of #Marshall (EIVOM) overcomes heat-sink effects, facilitating mitral isthmus (MI) block, and may represent an effective adjunctive ablation strategy. We aimed to quantify the efficacy and safety of EIVOM through a meta-analysis of… Continue reading Ethanol Infusion of the Vein of Marshall-Based Strategies for Persistent Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Trials
Evaluation of Rabeprazole for Gastrointestinal Protection in Acute Coronary Syndrome Patients Treated with Aspirin and Ticagrelor: A Pilot Study
Purpose: Patients with acute coronary syndrome (#ACS ) on ticagrelor-based dual antiplatelet therapy (#DAPT ) have an increased risk of gastrointestinal (GI) bleeding. However, evidence supporting the protective role of proton pump inhibitors against DAPT-induced gastric mucosal injury remains limited.Materials and methods: This was a single-center, prospective, open-label, observational trial enrolling patients with ACS who… Continue reading Evaluation of Rabeprazole for Gastrointestinal Protection in Acute Coronary Syndrome Patients Treated with Aspirin and Ticagrelor: A Pilot Study
Electroacupuncture for slow flow/no-reflow in patients with acute myocardial infarction undergoing percutaneous coronary intervention: a pilot randomized controlled trial
Background: Slow flow/no-reflow (SF-NR) complicates up to 44% of percutaneous #coronary interventions ( #PCI) for acute myocardial infarction (#AMI), worsening prognosis. Electroacupuncture (EA) may mitigate SF-NR, but clinical evidence is limited.Objective: This trial was designed to assess the feasibility and effectiveness of intraoperative EA in reducing SF-NR during PCI for AMI patients.Design setting and participants… Continue reading Electroacupuncture for slow flow/no-reflow in patients with acute myocardial infarction undergoing percutaneous coronary intervention: a pilot randomized controlled trial
Measurement of blood pressure in European Society of Hypertension Excellence Centres: A survey by the Young Investigators Group of the European Society of Hypertension
Background: Office blood #pressure (BP) measurement is the cornerstone of #hypertension diagnosis and risk stratification. Inaccurate BP readings can lead to significant misclassification, often overestimating BP and prompting unnecessary lifelong treatment. The Young Investigators Group of the European Society of Hypertension (YIG-ESH) conducted a structured, comprehensive survey among ESH Excellence Centres with the primary objective… Continue reading Measurement of blood pressure in European Society of Hypertension Excellence Centres: A survey by the Young Investigators Group of the European Society of Hypertension
The Impact of Coffee Consumption on Mortality Among Patients With Heart Failure
Aims: To assess the relationship between #coffee consumption and all-cause mortality in heart failure (#HF ) patients, using data from the National Health and Nutrition Examination Survey (NHANES).Methods and results: We analyzed data from NHANES (2003-2018), including 915 participants with HF who reported daily caffeine intake. Participants were categorized into coffee consumption levels: zero, one,… Continue reading The Impact of Coffee Consumption on Mortality Among Patients With Heart Failure
Efficacy and Safety of Sodium-Glucose Cotransporter 2 Inhibitors (SGLT2i) in Cardiac Amyloidosis: A Systematic Review
Introduction: Cardiac #amyloidosis is an underdiagnosed cause of heart failure characterized by extracellular deposition of misfolded proteins, most commonly transthyretin (ATTR) or immunoglobulin light chains (AL). Despite recent advances in disease-modifying therapies, prognosis remains poor. Sodium-glucose cotransporter 2 inhibitors ( #SGLT2i ) have demonstrated cardiovascular and renal benefits. However, evidence regarding their safety and efficacy… Continue reading Efficacy and Safety of Sodium-Glucose Cotransporter 2 Inhibitors (SGLT2i) in Cardiac Amyloidosis: A Systematic Review
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