Background/Objectives: Collagen is a protein formed by very long amino acid chains. When conveniently treated, it can incorporate water into the net, thus increasing its volume and mass. The present work aimed to evaluate the potential anti-obesity effects of bovine collagen that has been technologically treated to increase its water retention capacity in an acid… Continue reading Anti- #Obesity Effects of a #Collagen with Low Digestibility and High Swelling Capacity: A Human Randomized Control Trial
Tag: Obesity
Low-Calorie, High-Protein Ketogenic #Diet Versus Low-Calorie, Low-Sodium, and High-Potassium Mediterranean Diet in Overweight Patients and Patients with #Obesity with High-Normal Blood Pressure or Grade I #Hypertension: The Keto–Salt Pilot Study
Background and Objective: Dietary interventions are the first-line treatment for overweight individuals (OW) and individuals with obesity (OB) with high-normal blood pressure (BP) or grade I hypertension, especially when at low-to-moderate cardiovascular risk (CVR). However, current guidelines do not specify the most effective dietary approach for optimising cardiovascular and metabolic outcomes in this population. This… Continue reading Low-Calorie, High-Protein Ketogenic #Diet Versus Low-Calorie, Low-Sodium, and High-Potassium Mediterranean Diet in Overweight Patients and Patients with #Obesity with High-Normal Blood Pressure or Grade I #Hypertension: The Keto–Salt Pilot Study
Lifetime Health Effects and Cost-Effectiveness of #Tirzepatide and #Semaglutide in US Adults
Importance Newer antiobesity medications lead to greater weight loss and lower cardiometabolic risks. However, the high costs of these medications have raised policy questions about their value and coverage decisions.Objective To compare the cost-effectiveness of 4 antiobesity medications with lifestyle modification vs lifestyle modification alone in the US.Design, Setting, and Participants A lifetime cost-effectiveness analysis… Continue reading Lifetime Health Effects and Cost-Effectiveness of #Tirzepatide and #Semaglutide in US Adults
Definition and diagnostic criteria of clinical #obesity
Current BMI-based measures of obesity can both underestimate and overestimate adiposity and provide inadequate information about health at the individual level, which undermines medically-sound approaches to health care and policy. This Commission sought to define clinical obesity as a condition of illness that, akin to the notion of chronic disease in other medical specialties, directly… Continue reading Definition and diagnostic criteria of clinical #obesity
#Cardiovascular risk and #obesity impact loss of grey matter volume earlier in males than females
Background It remains imperative to discover the time course that cardiovascular risk factors influence neurodegeneration in males and females and decipher whether the apolipoprotein (APOE) genotype mediates this relationship. Here we perform a large-scale evaluation of the influence of cardiovascular risk and obesity on brain volume in males and females in different age groups.Methods 34… Continue reading #Cardiovascular risk and #obesity impact loss of grey matter volume earlier in males than females
Once-Weekly #Semaglutide in Persons with #Obesity and #Knee Osteoarthritis
BackgroundWeight reduction has been shown to alleviate symptoms of osteoarthritis of the knee, including pain. The effect of glucagon-like peptide-1 receptor agonists on outcomes in knee osteoarthritis among persons with obesity has not been well studied.MethodsWe conducted a 68-week, double-blind, randomized, placebo-controlled trial at 61 sites in 11 countries. Participants with obesity (a body-mass index… Continue reading Once-Weekly #Semaglutide in Persons with #Obesity and #Knee Osteoarthritis
Maternal #Obesity and Risk of Sudden Unexpected Infant Death
Importance Rates of maternal obesity are increasing in the US. Although obesity is a well-documented risk factor for numerous poor pregnancy outcomes, it is not currently a recognized risk factor for sudden unexpected infant death (SUID).Objective To determine whether maternal obesity is a risk factor for SUID and the proportion of SUID cases attributable to maternal obesity.Design,… Continue reading Maternal #Obesity and Risk of Sudden Unexpected Infant Death
(OR02-02-24) Identification of a Novel Multi-target Bioactive Compound With Anti-#obesity and Anti-#diabetic Activities
Objectives: Insulin resistance and progressive decline in functional β-cell mass are two key factors for developing type 2 diabetes (T2D), which is largely driven by overweight and obesity, a significant obstacle for effective metabolic control in many patients with T2D. We recently found that elenolic acid (EA), a small molecule derived from olive can directly stimulate intestinal… Continue reading (OR02-02-24) Identification of a Novel Multi-target Bioactive Compound With Anti-#obesity and Anti-#diabetic Activities
#Glucagon-like peptide-1 receptor agonists and #stroke: A systematic review and meta-analysis of #cardiovascular outcome trials
Background:In patients surviving stroke, approximately 15% and 60% exhibit concurrent diabetes mellitus and overweight/obesity, respectively, necessitating heightened secondary prevention efforts. Despite glucagon-like peptide-1 receptor agonists (GLP-1 RAs) demonstrating improved outcomes for those with diabetes mellitus or obesity, their underutilization persists among eligible individuals. This systematic review and meta-analysis investigated the impact of GLP-1 RAs on… Continue reading #Glucagon-like peptide-1 receptor agonists and #stroke: A systematic review and meta-analysis of #cardiovascular outcome trials
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