INTRODUCTIONIn mammals, the early-life period after birth is a time of profound immune development during which the generation of appropriate responses to newly encountered commensal and environmental antigens is crucial for maintaining health. Breast milk is positioned to regulate nascent mucosal immune responses through the delivery of live microbes, commensal-selecting oligosaccharides, maternal cells, and immunomodulatory… Continue reading Breast #milk IgG engages the mouse #neonatal #immune system to instruct responses to #gut #antigens
Tag: milk
The effect of #camel #milk on house dust mite allergen induced #asthma model in BALB/C mice
Camel milk has demonstrated robust immunomodulatory and anti-inflammatory properties in various clinical and experimental studies. However, no previous studies have characterized the cellular immunological effects of camel milk in the context of allergic asthma. Therefore, the present work aimed to evaluate the protective effects of camel milk in house dust mite induced asthma in mice,… Continue reading The effect of #camel #milk on house dust mite allergen induced #asthma model in BALB/C mice
Non-fermented and fermented #milk intake in relation to risk of ischemic #heart disease and to circulating cardiometabolic proteins in swedish women and men: Two prospective longitudinal cohort studies with 100,775 participants
BackgroundThe effect of milk on the risk of ischemic heart disease (IHD) and acute myocardial infarction (MI) is unclear. We aimed to examine the association between non-fermented and fermented milk consumption on these endpoints and investigate the relationship between milk intake and cardiometabolic-related proteins in plasma.MethodsOur study is based on two Swedish prospective cohort studies… Continue reading Non-fermented and fermented #milk intake in relation to risk of ischemic #heart disease and to circulating cardiometabolic proteins in swedish women and men: Two prospective longitudinal cohort studies with 100,775 participants
Non-fermented and fermented #milk intake in relation to risk of ischemic #heart disease and to circulating cardiometabolic proteins in swedish #women and men: Two prospective longitudinal cohort studies with 100,775 participants
BackgroundThe effect of milk on the risk of ischemic heart disease (IHD) and acute myocardial infarction (MI) is unclear. We aimed to examine the association between non-fermented and fermented milk consumption on these endpoints and investigate the relationship between milk intake and cardiometabolic-related proteins in plasma.MethodsOur study is based on two Swedish prospective cohort studies… Continue reading Non-fermented and fermented #milk intake in relation to risk of ischemic #heart disease and to circulating cardiometabolic proteins in swedish #women and men: Two prospective longitudinal cohort studies with 100,775 participants
Maternal gut microbiome–induced IgG regulates neonatal gut microbiome and immunity
Breast milk IgG adds valueAlthough the most abundant class of antibody present in breast milk is IgA, maternal IgG antibodies also get transferred into breast milk via the neonatal Fc receptor. Sanidad et al. used mouse models to investigate the capacity of breast milk IgG to protect against pathogens and promote the establishment of a… Continue reading Maternal gut microbiome–induced IgG regulates neonatal gut microbiome and immunity
Evidence for a causal association between #milk intake and cardiometabolic disease outcomes using a two-sample Mendelian Randomization analysis in up to 1,904,220 individuals
High milk intake has been associated with cardio-metabolic risk. We conducted a Mendelian Randomization (MR) study to obtain evidence for the causal relationship between milk consumption and cardio-metabolic traits using the lactase persistence (LCT-13910 C > T, rs4988235) variant as an instrumental variable. MethodsWe tested the association of LCT genotype with milk consumption (for validation) and with… Continue reading Evidence for a causal association between #milk intake and cardiometabolic disease outcomes using a two-sample Mendelian Randomization analysis in up to 1,904,220 individuals
Reservoirs of antimicrobial resistance genes in retail raw milk
Background It has been estimated that at least 3% of the USA population consumes unpasteurized (raw) milk from animal sources, and the demand to legalize raw milk sales continues to increase. However, consumption of raw milk can cause foodborne illness and be a source of bacteria containing transferrable antimicrobial resistance genes (ARGs). To obtain a… Continue reading Reservoirs of antimicrobial resistance genes in retail raw milk
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