A single bout of physical #exercise improves 1-hour post-load plasma #glucose in healthy young adults

PurposePhysical exercise is a key component in the treatment of type 2 diabetes and plays an important role in maintaining a healthy glucose metabolism even in healthy subjects. To date, no studies have investigated the effect of a single bout of aerobic physical exercise on glucose metabolism in young, moderately active, healthy adults.MethodsWe performed an… Continue reading A single bout of physical #exercise improves 1-hour post-load plasma #glucose in healthy young adults

Impact of #lifestyle moderate-to-vigorous #physical activity timing on #glycemic control in sedentary adults with #overweight/obesity and metabolic impairments

ObjectiveModerate-to-vigorous physical activity (MVPA) improves glucose levels; however, whether its timing affects daily glycemic control remains unclear. This study aims to investigate the impact of lifestyle MVPA timing on daily glycemic control in sedentary adults with overweight/obesity and metabolic impairments.MethodsA total of 186 adults (50% women; age, 46.8 [SD 6.2] years) with overweight/obesity (BMI, 32.9… Continue reading Impact of #lifestyle moderate-to-vigorous #physical activity timing on #glycemic control in sedentary adults with #overweight/obesity and metabolic impairments

Acute Vigorous #Exercise Decreases Subsequent Non-Exercise Physical Activity and Body Temperature Linked to #Weight Gain

Purpose Exercise benefits the body and mind, but its weight loss effect is less than generally expected. Although this phenomenon is likely due to an exercise intensity-dependent decrease in non-exercise physical activity (NEPA), resulting in a decrease in non-exercise activity thermogenesis, the underlying mechanisms and effects of exercise intensity remain unknown. Here we show that acute… Continue reading Acute Vigorous #Exercise Decreases Subsequent Non-Exercise Physical Activity and Body Temperature Linked to #Weight Gain

Chronic Effects of Static #Stretching Exercises on Muscle #Strength and Power in Healthy Individuals Across the Lifespan: A Systematic Review with Multi-level Meta-analysis

The current literature on the chronic effects of static stretching (SS) exercises on muscle strength and power is unclear and controversial.ObjectiveWe aimed to examine the chronic effects of SS exercises on muscle strength and power as well as flexibility in healthy individuals across the lifespan.DesignSystematic review with meta-analysis of (randomized) controlled trials.Data SourcesA systematic literature… Continue reading Chronic Effects of Static #Stretching Exercises on Muscle #Strength and Power in Healthy Individuals Across the Lifespan: A Systematic Review with Multi-level Meta-analysis

Elucidating regulatory processes of intense #physical activity by multi-omics analysis

BackgroundPhysiological and biochemical processes across tissues of the body are regulated in response to the high demands of intense physical activity in several occupations, such as firefighting, law enforcement, military, and sports. A better understanding of such processes can ultimately help improve human performance and prevent illnesses in the work environment.MethodsTo study regulatory processes in… Continue reading Elucidating regulatory processes of intense #physical activity by multi-omics analysis

Effect of aerobic #exercise on #erectile function: systematic review and meta-analysis of randomized controlled trials

The health benefits of regular aerobic exercise are well established, although there is limited high-quality evidence regarding its impact on erectile function.AimTo determine the effect of aerobic exercise on erectile function in men and to identify factors that may influence this effect.MethodsThis systematic review and meta-analysis included randomized controlled trials that evaluated the effects of… Continue reading Effect of aerobic #exercise on #erectile function: systematic review and meta-analysis of randomized controlled trials

#Walking more than five flights of stairs a day can cut risk of #heart disease by 20% – Study

Forget walking 10,000 steps a day. Taking at least 50 steps climbing stairs each day could significantly slash your risk of heart disease, according to a new study from Tulane University. The study, published in Atherosclerosis, found that climbing more than five flights of stairs daily could reduce risk of cardiovascular disease by 20%. Atherosclerotic… Continue reading #Walking more than five flights of stairs a day can cut risk of #heart disease by 20% – Study

Irisin reduces #amyloid-β by inducing the release of neprilysin from #astrocytes following downregulation of ERK-STAT3 signaling

A pathological hallmark of Alzheimer’s disease (AD) is the deposition of amyloid-β (Aβ) protein in the brain. Physical exercise has been shown to reduce Aβ burden in various AD mouse models, but the underlying mechanisms have not been elucidated. Irisin, an exercise-induced hormone, is the secreted form of fibronectin type-III-domain-containing 5 (FNDC5). Here, using a… Continue reading Irisin reduces #amyloid-β by inducing the release of neprilysin from #astrocytes following downregulation of ERK-STAT3 signaling

Accelerometer-Derived “Weekend Warrior” Physical Activity and Incident Cardiovascular Disease

Guidelines recommend 150 minutes or more of moderate to vigorous physical activity (MVPA) per week for overall health benefit, but the relative effects of concentrated vs more evenly distributed activity are unclear.Objective  To examine associations between an accelerometer-derived “weekend warrior” pattern (ie, most MVPA achieved over 1-2 days) vs MVPA spread more evenly with risk of… Continue reading Accelerometer-Derived “Weekend Warrior” Physical Activity and Incident Cardiovascular Disease