BackgroundEpidemiologic research suggests that youth cannabis use is associated with psychotic disorders. However, current evidence is based heavily on 20th-century data when cannabis was substantially less potent than today.MethodsWe linked population-based survey data from 2009 to 2012 with records of health services covered under universal healthcare in Ontario, Canada, up to 2018. The cohort included… Continue reading Age-dependent association of #cannabis use with risk of #psychotic disorder
Tag: cannabis
Cannabis legalization and childhood asthma in the United States: An ecologic analysis
Cannabis use is increasing among adults with children in the home particularly in states with cannabis legalization for medical (MCL) and/or recreational use (RCL), relative to states where cannabis use remains illegal at the state level. Exposure to secondhand smoke is a key risk factor for asthma among children. The objective of the current study… Continue reading Cannabis legalization and childhood asthma in the United States: An ecologic analysis
Association of Mental Health Burden With Prenatal Cannabis Exposure From Childhood to Early AdolescenceLongitudinal Findings From the Adolescent Brain Cognitive Development (ABCD) Study
Dramatic increases in cannabis use during pregnancy are alarming because of evidence that prenatal exposure may be associated with a host of adverse outcomes. We previously found that prenatal cannabis exposure (PCE) following maternal knowledge of pregnancy is associated with increased psychopathology during middle childhood using baseline data from the Adolescent Brain Cognitive Development (ABCD) study.Here,… Continue reading Association of Mental Health Burden With Prenatal Cannabis Exposure From Childhood to Early AdolescenceLongitudinal Findings From the Adolescent Brain Cognitive Development (ABCD) Study
Cannabis use and risks of respiratory and all-cause morbidity and mortality: a population-based, data-linkage, cohort study
Introduction Although cannabis is frequently used worldwide, its impact on respiratory health is characterised by controversy. Objective To evaluate the association between cannabis use and respiratory-related emergency room (ER) visits and hospitalisations. Methods A retrospective, population-based, cohort study was carried out, linking health survey and health administrative data for residents of Ontario, Canada, aged 12–65… Continue reading Cannabis use and risks of respiratory and all-cause morbidity and mortality: a population-based, data-linkage, cohort study
The associations between prenatal #cannabis use disorder and neonatal outcomes
Background and AimsCannabis use disorder (CUD) during pregnancy has increased dramatically in the United States (US). This study examined the associations between prenatal CUD and adverse neonatal outcomes and heterogeneities in the associations by mothers’ tobacco use status and race/ethnicity. DesignPopulation-based, retrospective cohort study. SettingCalifornia, USA. ParticipantsA total of 4.83 million mothers who delivered a… Continue reading The associations between prenatal #cannabis use disorder and neonatal outcomes
Associations between adolescent #cannabis use and young-adult functioning in three longitudinal twin studies
Observational studies have linked cannabis use to an array of negative outcomes, including psychiatric symptoms, cognitive impairment, and educational and occupational underachievement. These associations are particularly strong when cannabis use occurs in adolescence. Nevertheless, causality remains unclear. The purpose of the present study was thus to examine associations between prospectively assessed adolescent cannabis use and… Continue reading Associations between adolescent #cannabis use and young-adult functioning in three longitudinal twin studies
The effects of #alcohol and #cannabis use on the cortical thickness of #cognitive control and salience brain networks in emerging adulthood: a cotwin control study
Background Impairments in inhibitory control and its underlying brain networks (control/salience areas) are associated with substance misuse. Research often assumes a causal substance exposure effect on brain structure. This assumption remains largely untested and other factors (e.g., familial risk) may confound exposure effects. We leveraged a genetically-informative sample of 24-year-old twins and a quasi-experimental cotwin… Continue reading The effects of #alcohol and #cannabis use on the cortical thickness of #cognitive control and salience brain networks in emerging adulthood: a cotwin control study
Dynamic functional connectivity between nucleus accumbens and the central executive network relates to chronic cannabis use
The neural mechanisms of drug cue‐reactivity regarding the temporal fluctuations of functional connectivity, namely the dynamic connectivity, are sparsely studied. Quantifying the task‐modulated variability in dynamic functional connectivity at cue exposure can aid the understanding. We analyzed changes in dynamic connectivity in 54 adult cannabis users and 90 controls during a cannabis cue exposure task.… Continue reading Dynamic functional connectivity between nucleus accumbens and the central executive network relates to chronic cannabis use
Association of #Depression, #Anxiety, and Trauma With #Cannabis Use During Pregnancy
..Depression, anxiety, and trauma diagnoses and symptoms were associated with higher odds of cannabis use among pregnant women in California. These results support previous qualitative findings that pregnant women self-report using cannabis to manage mood and stress and suggest a dose-response association, with higher odds of cannabis use associated with co-occurring depressive and anxiety disorders… Continue reading Association of #Depression, #Anxiety, and Trauma With #Cannabis Use During Pregnancy
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