The Impact of Gut #Microbiota on the Development of #Anxiety Symptoms—A Narrative Review

The gut microbiota plays a key role in mental health, with growing evidence linking its composition to anxiety and depressive disorders. Research on this topic has expanded significantly in recent years. This review explores alterations in the gut microbiota of individuals with anxiety disorders and examines the potential therapeutic effects of probiotics. Background/Objectives: This review… Continue reading The Impact of Gut #Microbiota on the Development of #Anxiety Symptoms—A Narrative Review

Adverse health effects of #5G mobile networking technology under real-life conditions

Highlights•Identifies wide-spectrum of adverse health effects of non-ionizing non-visible radiation.•Most laboratory experiments were not designed to identify the more severe adverse effects reflective of real-life conditions.•Many experiments do not include the real-life pulsing and modulation of the carrier signal.•Vast majority of experiments do not account for synergistic adverse effects of other toxic stimuli with wireless… Continue reading Adverse health effects of #5G mobile networking technology under real-life conditions

Human #microplastic removal: what does the evidence tell us?

The increased levels of microplastics and nanoplastics (MNPs) found in human brain tissue are alarming, particularly in patients with dementia. Although total avoidance of MNP exposure will likely remain an unattainable endpoint in light of their ubiquity in the environment, new studies indicate feasible pathways by which dietary intake may be decreased or clearances improved.… Continue reading Human #microplastic removal: what does the evidence tell us?

Long-Term Exposure to Non-Steroidal Anti-Inflammatory Medication in Relation to #Dementia Risk

BackgroundNon-steroidal anti-inflammatory (NSAID) medication could reduce dementia risk due to anti-inflammatory and possibly amyloid-lowering properties. However, the results of observational studies and short-term randomized-controlled trials have been inconsistent, and duration and dose–response relationships are still unclear.MethodsWe included 11,745 dementia-free participants from the prospective population-based Rotterdam Study (59.5% female, mean age 66.2 years). NSAID use from 1991… Continue reading Long-Term Exposure to Non-Steroidal Anti-Inflammatory Medication in Relation to #Dementia Risk

#Life expectancy and years of life lost for adults with diagnosed #ADHD in the UK: matched cohort study

Nearly 3% of adults have attention-deficit and hyperactivity disorder (ADHD), although in the UK, most are undiagnosed. Adults with ADHD on average experience poorer educational and employment outcomes, worse physical and mental health and are more likely to die prematurely. No studies have yet used mortality data to examine the life expectancy deficit experienced by… Continue reading #Life expectancy and years of life lost for adults with diagnosed #ADHD in the UK: matched cohort study

Association of #Diet and #Waist-to-Hip Ratio With Brain Connectivity and #Memory in #Aging

Importance  Epidemiological studies suggest that lifestyle factors are associated with risk of dementia. However, few studies have examined the association of diet and waist to hip ratio (WHR) with hippocampus connectivity and cognitive health.Objective  To ascertain how longitudinal changes in diet quality and WHR during midlife are associated with hippocampal connectivity and cognitive function in… Continue reading Association of #Diet and #Waist-to-Hip Ratio With Brain Connectivity and #Memory in #Aging

Suboptimal #dietary patterns are associated with accelerated biological #aging in young adulthood: A study with twins

Background & aimsSuboptimal diets increase morbidity and mortality risk. Epigenetic clocks are algorithms that can assess health and lifespan, even at a young age, before clinical manifestations of diseases. We investigated the association between dietary patterns and biological aging in young adult twins.MethodsThe data were drawn from the population-based FinnTwin12 study and consisted of twins… Continue reading Suboptimal #dietary patterns are associated with accelerated biological #aging in young adulthood: A study with twins

A dual-pathway architecture for #stress to disrupt agency and promote #habit

Chronic stress can change how we learn and, thus, how we make decisions1,2,3,4,5. Here we investigated the neuronal circuit mechanisms that enable this. Using a multifaceted systems neuroscience approach in male and female mice, we reveal a dual-pathway, amygdala–striatal neuronal circuit architecture by which a recent history of chronic stress disrupts the action–outcome learning underlying… Continue reading A dual-pathway architecture for #stress to disrupt agency and promote #habit

#Higher income is associated with greater life satisfaction, and more #stress

Is there a cost to our well-being from increased affluence? Drawing upon responses from 2.05 million U.S. adults from the Gallup Daily Poll from 2008 to 2017 we find that with household income above ~$63,000 respondents are more likely to experience stress. This contrasts with the trend below this threshold, where at higher income the… Continue reading #Higher income is associated with greater life satisfaction, and more #stress