Early-stage esophageal cancers show better treatment response but are harder to detect. Li et al. developed a deep learning pipeline to aid clinicians in identifying early-stage, high-risk esophageal lesions and tested it in a randomized clinical trial in patients undergoing endoscopy. Deep learning assistance doubled the detection of high-risk esophageal lesions compared with the unassisted control group.… Continue reading Deep learning assists detection of #esophageal #cancer and precursor lesions in a prospective, randomized controlled study
Category: Tech
Are Blood Tests for #Alzheimer Disease Ready for Prime Time?
This is a transformative time for patients with Alzheimer disease. Alzheimer disease is increasingly viewed as a treatable condition and managed like other major chronic diseases, such as heart disease and cancer. Management of Alzheimer disease includes early diagnosis with molecular confirmation, disease-modifying treatments that are initiated early in the disease course, better risk reduction… Continue reading Are Blood Tests for #Alzheimer Disease Ready for Prime Time?
#Drone delivery of automated external #defibrillators compared with ambulance arrival in real-life suspected out-of-hospital cardiac arrests: a prospective observational study in Sweden
Background: A novel approach to improve bystander defibrillation for out-of-hospital cardiac arrests is to dispatch and deliver an automated external defibrillator (AED) directly to the suspected cardiac arrest location by drone. The aim of this study was to investigate how often a drone could deliver an AED before ambulance arrival and to measure the median time… Continue reading #Drone delivery of automated external #defibrillators compared with ambulance arrival in real-life suspected out-of-hospital cardiac arrests: a prospective observational study in Sweden
#Screen Media Use and #Mental Health of Children and AdolescentsA Secondary Analysis of a Randomized Clinical Trial
Importance Excessive screen media use has been associated with poorer mental health among children and adolescents in several observational studies. However, experimental evidence supporting this hypothesis is lacking.Objective To investigate the effects of a 2-week screen media reduction intervention on children’s and adolescents’ mental health.Design, Setting, and Participants This prespecified secondary analysis of a cluster randomized clinical trial… Continue reading #Screen Media Use and #Mental Health of Children and AdolescentsA Secondary Analysis of a Randomized Clinical Trial
#AI-based differential diagnosis of #dementia etiologies on multimodal data
Differential diagnosis of dementia remains a challenge in neurology due to symptom overlap across etiologies, yet it is crucial for formulating early, personalized management strategies. Here, we present an artificial intelligence (AI) model that harnesses a broad array of data, including demographics, individual and family medical history, medication use, neuropsychological assessments, functional evaluations and multimodal… Continue reading #AI-based differential diagnosis of #dementia etiologies on multimodal data
An ingestible device for #gastric electrophysiology
The ability to record high-quality electrophysiology data from the gastrointestinal tract and enteric nervous system is of use in understanding a variety of disorders and improving healthcare via early diagnosis. However, such measurements remain challenging because electrodes must be implanted surgically or worn on the skin, which results in a trade-off between signal quality and… Continue reading An ingestible device for #gastric electrophysiology
#Smartphone application versus written material for #smoking reduction and cessation in individuals undergoing low-dose computed tomography (LDCT) screening for lung cancer: a phase II open-label randomised controlled trial
BackgroundCounseling, nicotine replacement, and other cessation medications have been proven effective in smoking cessation. The wide-scale adoption of smartphones and other mobile devices has opened new possibilities for scalable and personalized smoking cessation approaches. The study investigated whether a smartphone application would be more effective than written material for smoking cessation and reduction in smoking… Continue reading #Smartphone application versus written material for #smoking reduction and cessation in individuals undergoing low-dose computed tomography (LDCT) screening for lung cancer: a phase II open-label randomised controlled trial
#Virtual reality for #pain management in hospitalized patients with #cancer: A randomized controlled trial
Hospitalized patients with cancer often experience acute and/or chronic pain. Although virtual reality (VR) has been extensively studied across a wide range of clinical settings, no studies have yet evaluated potential impact on pain management in this patient population.MethodsProspective randomized controlled trial at an urban academic hospital comparing VR against an active control to mitigate… Continue reading #Virtual reality for #pain management in hospitalized patients with #cancer: A randomized controlled trial
#Light stimulation of mitochondria reduces blood #glucose levels
Mitochondria regulate metabolism, but solar light influences its rate. Photobiomodulation (PBM) with red light (670 nm) increases mitochondrial membrane potentials and adenosine triphosphate production and may increase glucose demand. Here we show, with a glucose tolerance test, that PBM of normal subjects significantly reduces blood sugar levels. A 15 min exposure to 670 nm light reduced the degree… Continue reading #Light stimulation of mitochondria reduces blood #glucose levels
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