Vitamin D is best known for its role in maintaining bone health and calcium homeostasis. However, it also exerts a broad range of extra-skeletal effects on cellular physiology and on the immune system. Vitamins D2 and D3 share a high degree of structural similarity. Functional equivalence in their vitamin D-dependent effects on human physiology is… Continue reading Vitamins D2 and D3 Have Overlapping But Different Effects on the Human Immune System Revealed Through Analysis of the Blood Transcriptome
Category: supplements
Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis of Early COVID-19 and Treated at Home Within 3 Days or After 3 Days of Symptom Onset with Prescribed and Non-Prescribed Treatments Between November 2020 and August 2021
This retrospective study aimed to investigate outcomes and hospitalization rates in patients with a confirmed diagnosis of early COVID-19 treated at home with prescribed and non-prescribed treatments. MATERIAL AND METHODS: The medical records of a cohort of 158 Italian patients with early COVID-19 treated at home were analyzed. Treatments consisted of indomethacin, low-dose aspirin, omeprazole,… Continue reading Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis of Early COVID-19 and Treated at Home Within 3 Days or After 3 Days of Symptom Onset with Prescribed and Non-Prescribed Treatments Between November 2020 and August 2021
Vitamin D deficiency is associated with higher risks for SARS-CoV-2 infection and COVID-19 severity: a retrospective case–control study
Robust evidence of whether vitamin D deficiency is associated with COVID-19 infection and its severity is still lacking. The aim of the study was to evaluate the association between vitamin D levels and the risks of SARS-CoV-2 infection and severe disease in those infected. A retrospective study was carried out among members of Clalit Health… Continue reading Vitamin D deficiency is associated with higher risks for SARS-CoV-2 infection and COVID-19 severity: a retrospective case–control study
Vitamin #D supplementation reduces the risk of #fall in the vitamin D deficient elderly: an updated systematic review and meta-analysis
Vitamin D supplementation has been widely recommended to prevent falls. However, considerable controversy exists regarding the association of such supplementation and fall risk. Previous meta-analyses yielded inconsistent results because of differences in the baseline of 25-hydroxyvitamin D (25[OH]D) and dose of vitamin D and use of vitamin D or in combination with calcium in different… Continue reading Vitamin #D supplementation reduces the risk of #fall in the vitamin D deficient elderly: an updated systematic review and meta-analysis
A Systematic Review of Dietary #Supplements and Alternative Therapies for #Weight Loss
Dietary supplements and alternative therapies are commercialized as a panacea for obesity/weight gain as a result of the minimal regulatory requirements in demonstrating efficacy. These products may indirectly undermine the value of guideline-driven obesity treatments. Included in this study is a systematic review of the literature of purported dietary supplements and alternative therapies for weight… Continue reading A Systematic Review of Dietary #Supplements and Alternative Therapies for #Weight Loss
#Calcifediol treatment and #COVID-19-related outcomes
COVID-19 is a major health problem because of saturation of intensive care units (ICU) and mortality. Vitamin D has emerged as a potential treatment able to reduce the disease severity. ObjectiveTo elucidate the effect of calcifediol [25OHD3] treatment on COVID-19-related outcomes. DesignObservational cohort study from March to May, 2020. SettingPatients admitted to COVID-19 wards of… Continue reading #Calcifediol treatment and #COVID-19-related outcomes
#Glucosamine #Chondroitin and Mortality in a US NHANES Cohort
Background: Limited previous studies in the United Kingdom or a single US state have demonstrated an association between intake of glucosamine/chondroitin and mortality. This study sought to investigate the association between regular consumption of glucosamine/chondroitin and overall and cardiovascular (CVD) mortality in a national sample of US adults. Methods: Combined data from 16,686 participants in… Continue reading #Glucosamine #Chondroitin and Mortality in a US NHANES Cohort
The Efficacy and Safety of Vitamin #C for Iron Supplementation in Adult Patients With Iron Deficiency #Anemia
It remains uncertain whether vitamin C routinely used with oral iron supplements is essential for patients with iron deficiency anemia (IDA).. ..The primary outcome was the change in hemoglobin level from baseline to 2 weeks of treatment, and an equivalence margin of 1 g/dL in hemoglobin was chosen for the demonstration of comparable efficacy. Secondary… Continue reading The Efficacy and Safety of Vitamin #C for Iron Supplementation in Adult Patients With Iron Deficiency #Anemia
Vitamin #D for treatment of non‐alcoholic #fatty liver disease detected by transient elastography: A randomized, double‐blind, placebo‐controlled trial
To evaluate the effects of vitamin D on transient elastography (TE, FibroScan) indices of liver steatosis (controlled attenuation parameter [CAP]) and fibrosis (liver stiffness measurement [LSM]) in adults with non‐alcoholic fatty liver disease (NAFLD).. ..Both CAP and LSM gradually decreased in vitamin D‐treated patients and slightly increased in the placebo arm. Vitamin D was superior… Continue reading Vitamin #D for treatment of non‐alcoholic #fatty liver disease detected by transient elastography: A randomized, double‐blind, placebo‐controlled trial
