The Cognitive Debt hypothesis proposes that repetitive negative thinking (RNT), a modifiable process common to many psychological risk factors for Alzheimer's disease (AD) may itself increase risk. We sought to empirically examine relationships between RNT and markers of AD, compared with anxiety and depression symptoms. ..RNT was associated with decline in global cognition (P =… Continue reading Repetitive negative #thinking is associated with #amyloid, tau, and cognitive decline
Category: Psychiatry
Current and 1-Year Psychological and Physical Effects of Replacing Sedentary Time With Time in Other Behaviors
Sedentary time is inversely associated with health. Capturing 24 hours of behavior (i.e., sleep, sedentary, light physical activity, and moderate-to-vigorous physical activity) is necessary to understand behavior–health associations.. ..Cross-sectional analyses revealed substituting prolonged sedentary time for sleep was associated with lower stress (standardized β= −0.11), better mood (−0.12), and lower BMI (−0.10). Substituting total or… Continue reading Current and 1-Year Psychological and Physical Effects of Replacing Sedentary Time With Time in Other Behaviors
Screening for Anxiety in Adolescent and Adult Women: A Recommendation From the Women’s Preventive Services Initiative
..Recommendation: The WPSI recommends screening for anxiety in women and adolescent girls aged 13 years or older who are not currently diagnosed with anxiety disorders, including pregnant and postpartum women. Optimal screening intervals are unknown, and clinical judgment should be used to determine frequency. When screening suggests the presence of anxiety, further evaluation is necessary… Continue reading Screening for Anxiety in Adolescent and Adult Women: A Recommendation From the Women’s Preventive Services Initiative
Outcomes of Online #Mindfulness-Based Cognitive Therapy for Patients With Residual Depressive Symptoms A Randomized Clinical Trial
Patients with residual depressive symptoms face a gap in care because few resources, to date, are available to manage the lingering effects of their illness.. To evaluate the effectiveness for treating residual depressive symptoms with Mindful Mood Balance (MMB), a web-based application that delivers mindfulness-based cognitive therapy, plus usual depression care compared with usual depression… Continue reading Outcomes of Online #Mindfulness-Based Cognitive Therapy for Patients With Residual Depressive Symptoms A Randomized Clinical Trial
Loneliness around the world: Age, gender, and cultural differences in loneliness
Highlights •Younger people reported more loneliness than the middle-aged. •The middle-aged reported more loneliness than older people. •Men reported more loneliness than women. •People in individualistic (vs. collectivist) countries reported more loneliness. •Age, gender, and culture interacted to predict loneliness. https://bit.ly/3eYVzk2
Efficacy and Safety of a 2-Month Formulation of Aripiprazole Lauroxil With 1-Day Initiation in Patients Hospitalized for Acute Schizophrenia Transitioned to Outpatient Care
Evaluate efficacy and safety of a 2-month formulation of aripiprazole lauroxil (AL) with 1-day initiation during hospitalization for acute exacerbation of schizophrenia followed by transition to outpatient care.. The phase 3b double-blind Aripiprazole Lauroxil and Paliperidone palmitate: INitiation Effectiveness (ALPINE) study was conducted from November 2017 to March 2019. Adults with acute schizophrenia according to… Continue reading Efficacy and Safety of a 2-Month Formulation of Aripiprazole Lauroxil With 1-Day Initiation in Patients Hospitalized for Acute Schizophrenia Transitioned to Outpatient Care
#Cognitive behavioral group therapy for panic disorder in a general clinical setting: a prospective cohort study with 12 to 31-years follow-up
The long-term prognosis after cognitive behavioral therapy (CBT) in outpatient groups for panic disorder and agoraphobia is not well known. The purpose of this study was to assess long-term outcomes in terms of psychological health, health-related quality of life (HRQoL), quality of life (QoL) and treatment satisfaction after CBT for panic disorder and agoraphobia ..The… Continue reading #Cognitive behavioral group therapy for panic disorder in a general clinical setting: a prospective cohort study with 12 to 31-years follow-up
Assessment of a Prediction Model for Antidepressant Treatment Stability Using Supervised Topic Models
..Stable treatment response, intended as a proxy for treatment effectiveness, defined as continued prescription of an antidepressant for 90 days. Supervised topic models were used to extract 10 interpretable covariates from coded clinical data for stability prediction. With use of data from 1 hospital system (site A), generalized linear models and ensembles of decision trees… Continue reading Assessment of a Prediction Model for Antidepressant Treatment Stability Using Supervised Topic Models
Effects of #yoga on depressive symptoms in people with mental disorders: a systematic review and meta-analysis
..Eligibility criteria for selecting studies We included randomised controlled trials with a yoga intervention comprising ≥50% physical activity in adults with a recognised diagnosed mental disorder according to DSM-3, 4 or 5. Results 19 studies were included in the review (1080 participants) and 13 studies were included in the meta-analysis (632 participants). Disorders of depression,… Continue reading Effects of #yoga on depressive symptoms in people with mental disorders: a systematic review and meta-analysis
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