Relationship Among Sensory Over-Responsivity, Problem Behaviors, and #Anxiety in Emerging Adults with #Autism Spectrum Disorder

Despite the highly prevailing rate of sensory over-responsivity, problem behaviors, and anxiety among emerging adults with autism spectrum disorder (ASD), little is known about the nature of their experiences. While previous studies have indicated potential relationships among these conditions, their connections still need to be clarified. This study aimed to examine the relationships between sensory… Continue reading Relationship Among Sensory Over-Responsivity, Problem Behaviors, and #Anxiety in Emerging Adults with #Autism Spectrum Disorder

#Meningeal γδ T cells regulate #anxiety-like behavior via IL-17a signaling in neurons

Interleukin (IL)-17a has been highly conserved during evolution of the vertebrate immune system and widely studied in contexts of infection and autoimmunity. Studies suggest that IL-17a promotes behavioral changes in experimental models of autism and aggregation behavior in worms. Here, through a cellular and molecular characterization of meningeal γδ17 T cells, we defined the nearest… Continue reading #Meningeal γδ T cells regulate #anxiety-like behavior via IL-17a signaling in neurons

#Sleep duration and affective reactivity to #stressors and positive events in daily life

Objective: Experimental evidence suggests that inadequate sleep disrupts next-day affective processing and evokes greater stress reactivity. However, less research has focused on whether sleep predicts next-day affective reactivity to naturally occurring stressors and positive events in daily life, as well as the reversed direction of association (i.e., affective reactivity to daily events as predictors of… Continue reading #Sleep duration and affective reactivity to #stressors and positive events in daily life

The unfolding #COVID-19 pandemic: A probability-based, nationally representative study of #mental health in the U.S.

The COVID-19 pandemic is a collective stressor unfolding over time, yet rigorous published empirical studies addressing mental health consequences of COVID-19 among large probability-based national samples are rare. Between 3/18-4/18/20, during an escalating period of illness and death in the United States, we assessed acute stress, depressive symptoms and direct, community, and media-based exposures to… Continue reading The unfolding #COVID-19 pandemic: A probability-based, nationally representative study of #mental health in the U.S.

#Loneliness and type 2 #diabetes incidence: findings from the English Longitudinal Study of Ageing

Loneliness is associated with all-cause mortality and coronary heart disease. However, the prospective relationship between loneliness and type 2 diabetes onset is unclear.. ..A total of 264 (6.42%) participants developed type 2 diabetes over the follow-up period. Loneliness was a significant predictor of incident type 2 diabetes (HR 1.46; 95% CI 1.15, 1.84; p = 0.002) independent… Continue reading #Loneliness and type 2 #diabetes incidence: findings from the English Longitudinal Study of Ageing

#Depression and subsequent risk for incident rheumatoid #arthritis among women

We investigated the association of depression with subsequent risk of rheumatoid arthritis (RA) by serologic phenotype.. ..Among 195,358 women, we identified 858 incident RA cases (65% seropositive) over 3,087,556 person‐years (median 17.9 years/participant). Compared to women without depression, those with depression had multivariable HRs (95%CIs) of: 1.28(1.10‐1.48) for all RA; 1.12(0.93‐1.35) for seropositive RA; and… Continue reading #Depression and subsequent risk for incident rheumatoid #arthritis among women

Post-traumatic stress disorder as a risk factor for #dementia: systematic review and meta-analysis

Post-traumatic stress disorder (PTSD) has been identified as a potential risk factor for developing dementia. There are currently, however, no meta-analyses quantifying this risk.. ..PTSD was associated with a significant risk for all-cause dementia: pooled hazard ratio HR = 1.61 (95% CI 1.43–1.81, I2= 85.8%, P < 0.001; n = 1 693 678; 8 studies).… Continue reading Post-traumatic stress disorder as a risk factor for #dementia: systematic review and meta-analysis

It’s surprisingly nice to hear you: Misunderstanding the impact of #communication media can lead to suboptimal choices of how to connect with others.

Positive social connections improve wellbeing. Technology increasingly affords a wide variety of media that people can use to connect with others, but not all media strengthen social connection equally. Optimizing wellbeing, therefore, requires choosing how to connect with others wisely. We predicted that people’s preferences for communication media would be at least partly guided by… Continue reading It’s surprisingly nice to hear you: Misunderstanding the impact of #communication media can lead to suboptimal choices of how to connect with others.

Estimates of the Association of #Dementia With US #Mortality Levels Using Linked Survey and Mortality Records

..Of the 7342 total sample, 4348 participants (60.3%) were women. At baseline, 4533 individuals (64.0%) were between ages 70 and 79 years, 2393 individuals (31.0%) were between 80 and 89 years, and 416 individuals (5.0%) were between 90 and 99 years; percentages were weighted. The percentage of deaths attributable to dementia was 13.6% (95% CI,… Continue reading Estimates of the Association of #Dementia With US #Mortality Levels Using Linked Survey and Mortality Records