To determine whether the dietary inflammatory index (DII®) scores were associated with knee structural changes and pain over a 10.7-year follow-up.MethodsThis study utilised data from a prospective population-based cohort study (mean age 63 years, 51% female) in which 1,099, 875, 768 and 566 participants completed assessments at baseline, 2.6, 5.1 and 10.7 years, respectively. T1-weighted and T2-weighted… Continue reading #Dietary inflammatory index and MRI-detected #knee structural change and pain: a 10.7-year follow-up study
Category: Orthopedy
Silver─Gallium Nano-Amalgamated Particles as a Novel, Biocompatible Solution for #Antibacterial Coatings
Bacterial infections account for countless deaths globally. Antibiotics are the primary countermeasure; however, the alarming spread of antibiotic-resistant strains necessitates alternative solutions. Silver and silver compounds have emerged as promising antibacterial agents. However, issues related to cytotoxicity and genotoxicity of silver remain concern. To overcome these challenges, this proposes an easy-to-control and straightforward method to… Continue reading Silver─Gallium Nano-Amalgamated Particles as a Novel, Biocompatible Solution for #Antibacterial Coatings
Lower serum #testosterone is associated with increased likelihood of #arthritis
Studies have suggested that serum testosterone levels may be strongly correlated with the pathogenesis of arthritis. Therefore, the aim of this study was to assess the relationship between serum testosterone levels and arthritis in US adults using the National Health and Nutrition Examination Survey (NHANES). We used the database from NHANES, 2013–2016 to perform a… Continue reading Lower serum #testosterone is associated with increased likelihood of #arthritis
A two-cohort study on the association between the gut #microbiota and #bone density, microarchitecture, and strength
The gut microbiome affects the inflammatory environment through effects on T-cells, which influence the production of immune mediators and inflammatory cytokines that stimulate osteoclastogenesis and bone loss in mice. However, there are few large human studies of the gut microbiome and skeletal health. We investigated the association between the human gut microbiome and high resolution… Continue reading A two-cohort study on the association between the gut #microbiota and #bone density, microarchitecture, and strength
Opioid analgesia for acute low back pain and neck pain (the OPAL trial): a randomised placebo-controlled trial
Opioid analgesics are commonly used for acute low back pain and neck pain, but supporting efficacy data are scarce. We aimed to investigate the efficacy and safety of a judicious short course of an opioid analgesic for acute low back pain and neck pain.MethodsOPAL was a triple-blinded, placebo-controlled randomised trial that recruited adults (aged ≥18… Continue reading Opioid analgesia for acute low back pain and neck pain (the OPAL trial): a randomised placebo-controlled trial
The effect of mindfulness and motivational interviewing along with neuromuscular exercises on pain, function, and balance of women affected by knee osteoarthritis: a rater-blinded randomized controlled clinical trial
This study aimed to evaluate the effect of motivational interviewing (MI) and mindfulness (MF) added to neuromuscular (NM) exercises on improving pain, function, balance, and quality of life in patients with knee osteoarthritis (KOA).MethodsThis randomized clinical trial was conducted on sixty patients who were randomly assigned to the MI + NM, MF + NM, and NM groups. The groups… Continue reading The effect of mindfulness and motivational interviewing along with neuromuscular exercises on pain, function, and balance of women affected by knee osteoarthritis: a rater-blinded randomized controlled clinical trial
An overview of systematic reviews on the public health consequences of social isolation and loneliness
Highlights•There is consistent evidence linking social isolation and loneliness to worse cardiovascular and mental health outcomes.•Less is known on the role of other conditions and wider socio-economic consequences.•Policy makers and commissioners should consider asset-based prevention strategies. Social isolation and loneliness have been associated with ill health and are common in the developed world. A clear understanding… Continue reading An overview of systematic reviews on the public health consequences of social isolation and loneliness
Osteoporosis Medication Use After Hip Fracture in U.S. Patients Between 2002 and 2011
ABSTRACTHip fractures are common, morbid, costly, and associated with subsequent fractures. Historically, postfracture osteoporosis medication use rates have been poor, but have not been recently examined in a large-scale study. We conducted a retrospective, observational cohort study based on U.S. administrative insurance claims data for beneficiaries with commercial or Medicare supplemental health insurance. Eligible participants… Continue reading Osteoporosis Medication Use After Hip Fracture in U.S. Patients Between 2002 and 2011
Hip Fractures in Institutionalized Elderly People: Incidence Rates and Excess Mortality
It is assumed that nursing homes are the setting with the highest incidence of hip fractures. This observation is, however, based on very little data. The aim of this study was to analyze hip fracture rates and the associated excess mortality in a large nursing home population. A cohort of >69,000 women and men newly… Continue reading Hip Fractures in Institutionalized Elderly People: Incidence Rates and Excess Mortality
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