Opioid analgesics are commonly used for acute low back pain and neck pain, but supporting efficacy data are scarce. We aimed to investigate the efficacy and safety of a judicious short course of an opioid analgesic for acute low back pain and neck pain.MethodsOPAL was a triple-blinded, placebo-controlled randomised trial that recruited adults (aged ≥18… Continue reading Opioid analgesia for acute low back pain and neck pain (the OPAL trial): a randomised placebo-controlled trial
Category: Orthopedy
The effect of mindfulness and motivational interviewing along with neuromuscular exercises on pain, function, and balance of women affected by knee osteoarthritis: a rater-blinded randomized controlled clinical trial
This study aimed to evaluate the effect of motivational interviewing (MI) and mindfulness (MF) added to neuromuscular (NM) exercises on improving pain, function, balance, and quality of life in patients with knee osteoarthritis (KOA).MethodsThis randomized clinical trial was conducted on sixty patients who were randomly assigned to the MI + NM, MF + NM, and NM groups. The groups… Continue reading The effect of mindfulness and motivational interviewing along with neuromuscular exercises on pain, function, and balance of women affected by knee osteoarthritis: a rater-blinded randomized controlled clinical trial
An overview of systematic reviews on the public health consequences of social isolation and loneliness
Highlights•There is consistent evidence linking social isolation and loneliness to worse cardiovascular and mental health outcomes.•Less is known on the role of other conditions and wider socio-economic consequences.•Policy makers and commissioners should consider asset-based prevention strategies. Social isolation and loneliness have been associated with ill health and are common in the developed world. A clear understanding… Continue reading An overview of systematic reviews on the public health consequences of social isolation and loneliness
Osteoporosis Medication Use After Hip Fracture in U.S. Patients Between 2002 and 2011
ABSTRACTHip fractures are common, morbid, costly, and associated with subsequent fractures. Historically, postfracture osteoporosis medication use rates have been poor, but have not been recently examined in a large-scale study. We conducted a retrospective, observational cohort study based on U.S. administrative insurance claims data for beneficiaries with commercial or Medicare supplemental health insurance. Eligible participants… Continue reading Osteoporosis Medication Use After Hip Fracture in U.S. Patients Between 2002 and 2011
Hip Fractures in Institutionalized Elderly People: Incidence Rates and Excess Mortality
It is assumed that nursing homes are the setting with the highest incidence of hip fractures. This observation is, however, based on very little data. The aim of this study was to analyze hip fracture rates and the associated excess mortality in a large nursing home population. A cohort of >69,000 women and men newly… Continue reading Hip Fractures in Institutionalized Elderly People: Incidence Rates and Excess Mortality
‘Skeletal Age’ for mapping the impact of fracture on mortality
Fragility fracture is associated with an increased risk of mortality, but mortality is not part of doctor-patient communication. Here, we introduce a new concept called ‘Skeletal Age’ as the age of an individual’s skeleton resulting from a fragility fracture to convey the combined risk of fracture and fracture-associated mortality for an individual.Methods:We used the Danish… Continue reading ‘Skeletal Age’ for mapping the impact of fracture on mortality
Increased risk of osteoarthritis in patients with atopic disease
Objectives To determine the incidence of osteoarthrits (OA) in patients with atopic disease compared with matched non-exposed patients.Methods We conducted a retrospective cohort study with propensity score matching using claims data from Optum’s de-identified Clinformatics Data Mart (CDM) (January 2003 to June 2019) and electronic health record data from the Stanford Research Repository (STARR) (January 2010 to… Continue reading Increased risk of osteoarthritis in patients with atopic disease
Insight into the assembly of lipid-hyaluronan complexes in osteoarthritic conditions
Interactions between molecules in the synovial fluid and the cartilage surface may play a vital role in the formation of adsorbed films that contribute to the low friction of cartilage boundary lubrication. Osteoarthritis (OA) is the most common degenerative joint disease. Previous studies have shown that in OA-diseased joints, hyaluronan (HA) not only breaks down… Continue reading Insight into the assembly of lipid-hyaluronan complexes in osteoarthritic conditions
Migraine Headaches in Patients with Upper Extremity Compressive Neuropathy
Background: Upper extremity nerve compression syndromes and migraines caused by nerve entrapment have many similarities, including patient presentation, anatomical findings, and treatment by surgical decompression of affected nerves. Parallels between the two conditions point toward the possibility of shared predisposition. The aim of this study was to evaluate the relationship between migraine and upper extremity… Continue reading Migraine Headaches in Patients with Upper Extremity Compressive Neuropathy
2 Medical News 