This 16-week randomised controlled trial (8-week treatment followed by 8-week follow-up) evaluated the symptomatic improvement in patients with knee osteoarthritis on 3 sessions per week of acupuncture (TSWA) compared to 1 session per week of acupuncture (OSWA). Sixty participants were randomised to either the TSWA or the OSWA group in a 1:1 ratio. The primary… Continue reading #Acupuncture of different treatment frequencies in knee #osteoarthritis: a pilot randomised controlled trial
Category: Orthopedy
#Depression and subsequent risk for incident rheumatoid #arthritis among women
We investigated the association of depression with subsequent risk of rheumatoid arthritis (RA) by serologic phenotype.. ..Among 195,358 women, we identified 858 incident RA cases (65% seropositive) over 3,087,556 person‐years (median 17.9 years/participant). Compared to women without depression, those with depression had multivariable HRs (95%CIs) of: 1.28(1.10‐1.48) for all RA; 1.12(0.93‐1.35) for seropositive RA; and… Continue reading #Depression and subsequent risk for incident rheumatoid #arthritis among women
Effectiveness of #Curcuma longa Extract for the Treatment of Symptoms and Effusion–Synovitis of Knee #Osteoarthritis
To determine the efficacy of Curcuma longa extract (CL) for reducing knee symptoms and effusion–synovitis in patients with symptomatic knee osteoarthritis and knee effusion–synovitis.. ..2 capsules of CL (n = 36) or matched placebo (n = 34) per day for 12 weeks. Measurements: The 2 primary outcomes were changes in knee pain on a visual… Continue reading Effectiveness of #Curcuma longa Extract for the Treatment of Symptoms and Effusion–Synovitis of Knee #Osteoarthritis
Warmth Prevents #Bone Loss Through the Gut #Microbiota
Osteoporosis is the most prevalent metabolic bone disease, characterized by low bone mass and microarchitectural deterioration. Here, we show that warmth exposure (34°C) protects against ovariectomy-induced bone loss by increasing trabecular bone volume, connectivity density, and thickness, leading to improved biomechanical bone strength in adult female, as well as in young male mice. Transplantation of… Continue reading Warmth Prevents #Bone Loss Through the Gut #Microbiota
Effectiveness of a high volume injection as treatment for chronic #Achilles #tendinopathy: randomised controlled trial
.. Primary outcome was pain and function assessed using the validated Victorian Institute of Sports Assessment-Achilles (VISA-A) questionnaire at 24 weeks (analysed using a generalised estimation equations model). Secondary outcomes were patient satisfaction, return to sport, degree of ultrasonographic Doppler flow, visual analogue scale on 10 hop test, power and flexibility of the gastrocnemius and… Continue reading Effectiveness of a high volume injection as treatment for chronic #Achilles #tendinopathy: randomised controlled trial
The Association of Pain Sensitization and Conditioned Pain Modulation to Pain Patterns in #Knee #Osteoarthritis
To examine the cross‐sectional association of ascending pain mechanisms (APM), implicated in pain sensitization (PS), and descending pain modulation with pain patterns and unpredictability of pain The Multicenter Osteoarthritis (OA) Study is a longitudinal cohort of older adults with or at risk of knee OA. Peripheral and central APM were assessed using quantitative sensory tests… Continue reading The Association of Pain Sensitization and Conditioned Pain Modulation to Pain Patterns in #Knee #Osteoarthritis
Atypical Femur #Fracture Risk versus Fragility Fracture Prevention with #Bisphosphonates
Bisphosphonates are effective in reducing hip and osteoporotic fractures. However, concerns about atypical femur fractures have contributed to substantially decreased bisphosphonate use, and the incidence of hip fractures may be increasing. Important uncertainties remain regarding the association between atypical femur fractures and bisphosphonates and other risk factors.. ..Among 196,129 women, 277 atypical femur fractures occurred.… Continue reading Atypical Femur #Fracture Risk versus Fragility Fracture Prevention with #Bisphosphonates
Prevalence of Hip or Groin Pain in Adolescents: A Systematic Review and Meta‐Analysis
Musculoskeletal pain is a common cause of pain in adolescence and can be an important predictor of future pain. The prevalence of hip or groin pain that could potentially affect different adolescent populations has not yet been systematically reviewed. This systematic review aimed to determine the prevalence of hip or groin pain in this population.… Continue reading Prevalence of Hip or Groin Pain in Adolescents: A Systematic Review and Meta‐Analysis
New Therapy Reduces Chronic Low Back Pain in Large International Study
A new study hasfound that tanezumab, a monoclonal antibody that inhibits nerve activity, provides relief in patients with chronic low back pain, one of the leading reasons why people seek medical care and the number one cause of disability worldwide. “This demonstration of efficacy is a major breakthrough in the global search to develop non-opioid… Continue reading New Therapy Reduces Chronic Low Back Pain in Large International Study
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