Higher working #memory capacity and distraction-resistance associated with strategy (not action) #game playing in younger adults, but #puzzle game playing in older adults

Superior attention and Working Memory (WM) have been reported for habitual action video gamers compared to other gamers or non-players. With an online experiment we measured visuo-spatial WM capacity and ability to ignore distraction, and participants listed the video games they played. Categorising the 209 young adult participants (18–30 years) according to the game type… Continue reading Higher working #memory capacity and distraction-resistance associated with strategy (not action) #game playing in younger adults, but #puzzle game playing in older adults

Speakers of different #languages remember #visual scenes differently

Language can have a powerful effect on how people experience events. Here, we examine how the languages people speak guide attention and influence what they remember from a visual scene. When hearing a word, listeners activate other similar-sounding words before settling on the correct target. We tested whether this linguistic coactivation during a visual search… Continue reading Speakers of different #languages remember #visual scenes differently

American #Football Play and #Parkinson Disease Among Men

Importance  Parkinsonism and Parkinson disease (PD) are known to result from repetitive head impacts from boxing. Repetitive head impacts from American football may also be associated with increased risk of neurodegenerative pathologies that cause parkinsonism, yet in vivo research on the association between football play and PD is scarce and limited by small samples and equivocal… Continue reading American #Football Play and #Parkinson Disease Among Men

Regional, circuit and network heterogeneity of #brain abnormalities in #psychiatric disorders

The substantial individual heterogeneity that characterizes people with mental illness is often ignored by classical case–control research, which relies on group mean comparisons. Here we present a comprehensive, multiscale characterization of the heterogeneity of gray matter volume (GMV) differences in 1,294 cases diagnosed with one of six conditions (attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder,… Continue reading Regional, circuit and network heterogeneity of #brain abnormalities in #psychiatric disorders

Dietary wheat #gluten induces astro- and #microgliosis in the hypothalamus of male mice

Gluten, which is found in cereals such as wheat, rye and barley, makes up a major dietary component in most western nations, and has been shown to promote body mass gain and peripheral inflammation in mice. In the current study, we investigated the impact of gluten on central inflammation that is typically associated with diet-induced… Continue reading Dietary wheat #gluten induces astro- and #microgliosis in the hypothalamus of male mice

Cumulative Use of #Proton Pump Inhibitors and Risk of #Dementia: The Atherosclerosis Risk in Communities Study

Studies on the association between proton pump inhibitor (PPI) use and dementia report mixed results and do not examine the impact of cumulative PPI use. We evaluated the associations between current and cumulative PPI use and risk of incident dementia in the Atherosclerosis Risk in Communities (ARIC) Study.Methods. These analyses used participants from a community-based cohort… Continue reading Cumulative Use of #Proton Pump Inhibitors and Risk of #Dementia: The Atherosclerosis Risk in Communities Study

Low-Dose #Aspirin and the Risk of #Stroke and Intracerebral #Bleeding in Healthy Older People Secondary Analysis of a Randomized Clinical Trial

Low-dose aspirin has been widely used for primary and secondary prevention of stroke. The balance between potential reduction of ischemic stroke events and increased intracranial bleeding has not been established in older individuals.Objective  To establish the risks of ischemic stroke and intracranial bleeding among healthy older people receiving daily low-dose aspirin.Design, Setting, and Participants  This secondary analysis… Continue reading Low-Dose #Aspirin and the Risk of #Stroke and Intracerebral #Bleeding in Healthy Older People Secondary Analysis of a Randomized Clinical Trial

#IQ After Pediatric #Concussion

This study investigated IQ scores in pediatric concussion (ie, mild traumatic brain injury) versus orthopedic injury.METHODS:Children (N = 866; aged 8–16.99 years) were recruited for 2 prospective cohort studies from emergency departments at children’s hospitals (2 sites in the United States and 5 in Canada) ≤48 hours after sustaining a concussion or orthopedic injury. They completed… Continue reading #IQ After Pediatric #Concussion

#Constipation Associated with #Cognitive #Aging and Decline

Key Takeaways:Chronic constipation — one bowel movement every three days or more — could signal worsening cognition.People who were chronically constipated had worse cognition equal to three years of aging, according to the study, which is the first to look at constipation’s potential impact on the aging brain.The new findings add to mounting research aligning… Continue reading #Constipation Associated with #Cognitive #Aging and Decline