..In order to demonstrate the changes in end-tidal CO2 (ETCO2) and oxygen saturation (SpO2) before and after wearing a surgical mask, we used a convenience sample of 15 housestaff physicians without lung conditions (aged 31.1 1.9 years, 60% male) and 15 veterans with severe COPD (aged 71.6 8.7 years, FEV1 44.0 22.2%,… Continue reading Effect of Face #Masks on Gas Exchange in Healthy Persons and Patients with #COPD
Category: Infectivology
#HPV Vaccination and the Risk of Invasive #Cervical Cancer
The efficacy and effectiveness of the quadrivalent human papillomavirus (HPV) vaccine in preventing high-grade cervical lesions have been shown. However, data to inform the relationship between quadrivalent HPV vaccination and the subsequent risk of invasive cervical cancer are lacking.. ..During the study period, we evaluated girls and women for cervical cancer until their 31st birthday.… Continue reading #HPV Vaccination and the Risk of Invasive #Cervical Cancer
Fecal #Microbiota Transplant is Highly Effective in Real-World Practice: Initial Results from the FMT National Registry
Fecal microbiota transplantation (FMT) is commonly used for treatment of C. difficile infections (CDI), although prospective safety data are limited and real-world FMT practice and outcomes are not well described. The FMT National Registry was designed to assess FMT methods and both safety and effectiveness outcomes from North American FMT providers.. ..Of the first 259… Continue reading Fecal #Microbiota Transplant is Highly Effective in Real-World Practice: Initial Results from the FMT National Registry
Vitamin #D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with #COVID-19 infection
..Based on CDC criteria, among our study patients, 74% had severe COVID-19 infection and 32.8% were vitamin D sufficient. After adjusting for confounding factors, there was a significant association between vitamin D sufficiency and reduction in clinical severity, inpatient mortality serum levels of C-reactive protein (CRP) and an increase in lymphocyte percentage. Only 9.7% of… Continue reading Vitamin #D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with #COVID-19 infection
Effect of convalescent #blood products for patients with severe acute #respiratory infections of #viral etiology: a systematic review and meta-analysis
To determine whether convalescent blood products (CBPs) could offer a survival advantage for patients with severe acute respiratory infections (SARI) of viral etiology.. ..According to observational studies, the cases received CPBs showed a decline of all-cause mortality compared with cases without using (OR 0.36, 95% CI 0.23 to 0.56, P < 0.00001). The all-cause mortality in the… Continue reading Effect of convalescent #blood products for patients with severe acute #respiratory infections of #viral etiology: a systematic review and meta-analysis
Impact of the #COVID-19 Pandemic on #Mental Health: Real-Time Surveillance Using Google Trends
In the wake of COVID-19, the capacity to track emerging trends in mental health symptoms and needs will guide public health responses at multiple ecological levels. Using Google Trends to track population-level mental health-related Google searches in the United States, this investigation identified pandemic-associated spikes in searches related to anxiety symptoms and remote treatments for… Continue reading Impact of the #COVID-19 Pandemic on #Mental Health: Real-Time Surveillance Using Google Trends
Facial Masking for #Covid-19 — Potential for “#Variolation” as We Await a Vaccine
...SARS-CoV-2 has the protean ability to cause myriad clinical manifestations, ranging from a complete lack of symptoms to pneumonia, acute respiratory distress syndrome, and death. Recent virologic, epidemiologic, and ecologic data have led to the hypothesis that facial masking may also reduce the severity of disease among people who do become infected.3 This possibility is… Continue reading Facial Masking for #Covid-19 — Potential for “#Variolation” as We Await a Vaccine
Vitamin #D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with #COVID-19 infection
To investigate the association between serum 25-hydroxyvitamin D levels and its effect on adverse clinical outcomes, and parameters of immune function and mortality due to a SARS-CoV-2 infection.. ..Based on CDC criteria, among our study patients, 74% had severe COVID-19 infection and 32.8% were vitamin D sufficient. After adjusting for confounding factors, there was a… Continue reading Vitamin #D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with #COVID-19 infection
#Meningeal γδ T cells regulate #anxiety-like behavior via IL-17a signaling in neurons
Interleukin (IL)-17a has been highly conserved during evolution of the vertebrate immune system and widely studied in contexts of infection and autoimmunity. Studies suggest that IL-17a promotes behavioral changes in experimental models of autism and aggregation behavior in worms. Here, through a cellular and molecular characterization of meningeal γδ17 T cells, we defined the nearest… Continue reading #Meningeal γδ T cells regulate #anxiety-like behavior via IL-17a signaling in neurons
2 Medical News 