..Based on CDC criteria, among our study patients, 74% had severe COVID-19 infection and 32.8% were vitamin D sufficient. After adjusting for confounding factors, there was a significant association between vitamin D sufficiency and reduction in clinical severity, inpatient mortality serum levels of C-reactive protein (CRP) and an increase in lymphocyte percentage. Only 9.7% of… Continue reading Vitamin #D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with #COVID-19 infection
Category: Infectivology
Effect of convalescent #blood products for patients with severe acute #respiratory infections of #viral etiology: a systematic review and meta-analysis
To determine whether convalescent blood products (CBPs) could offer a survival advantage for patients with severe acute respiratory infections (SARI) of viral etiology.. ..According to observational studies, the cases received CPBs showed a decline of all-cause mortality compared with cases without using (OR 0.36, 95% CI 0.23 to 0.56, P < 0.00001). The all-cause mortality in the… Continue reading Effect of convalescent #blood products for patients with severe acute #respiratory infections of #viral etiology: a systematic review and meta-analysis
Impact of the #COVID-19 Pandemic on #Mental Health: Real-Time Surveillance Using Google Trends
In the wake of COVID-19, the capacity to track emerging trends in mental health symptoms and needs will guide public health responses at multiple ecological levels. Using Google Trends to track population-level mental health-related Google searches in the United States, this investigation identified pandemic-associated spikes in searches related to anxiety symptoms and remote treatments for… Continue reading Impact of the #COVID-19 Pandemic on #Mental Health: Real-Time Surveillance Using Google Trends
Facial Masking for #Covid-19 — Potential for “#Variolation” as We Await a Vaccine
...SARS-CoV-2 has the protean ability to cause myriad clinical manifestations, ranging from a complete lack of symptoms to pneumonia, acute respiratory distress syndrome, and death. Recent virologic, epidemiologic, and ecologic data have led to the hypothesis that facial masking may also reduce the severity of disease among people who do become infected.3 This possibility is… Continue reading Facial Masking for #Covid-19 — Potential for “#Variolation” as We Await a Vaccine
Vitamin #D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with #COVID-19 infection
To investigate the association between serum 25-hydroxyvitamin D levels and its effect on adverse clinical outcomes, and parameters of immune function and mortality due to a SARS-CoV-2 infection.. ..Based on CDC criteria, among our study patients, 74% had severe COVID-19 infection and 32.8% were vitamin D sufficient. After adjusting for confounding factors, there was a… Continue reading Vitamin #D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with #COVID-19 infection
#Meningeal γδ T cells regulate #anxiety-like behavior via IL-17a signaling in neurons
Interleukin (IL)-17a has been highly conserved during evolution of the vertebrate immune system and widely studied in contexts of infection and autoimmunity. Studies suggest that IL-17a promotes behavioral changes in experimental models of autism and aggregation behavior in worms. Here, through a cellular and molecular characterization of meningeal γδ17 T cells, we defined the nearest… Continue reading #Meningeal γδ T cells regulate #anxiety-like behavior via IL-17a signaling in neurons
Risk for Serious #Infection With Low-Dose #Glucocorticoids in Patients With #Rheumatoid Arthritis
Low-dose glucocorticoids are frequently used for the management of rheumatoid arthritis (RA) and other chronic conditions, but the safety of long-term use remains uncertain.. ..Associations between glucocorticoid dose (none, ≤5 mg/d, >5 to 10 mg/d, and >10 mg/d) and hospitalized infection were evaluated using inverse probability–weighted analyses, with 1-year cumulative incidence predicted from weighted models.… Continue reading Risk for Serious #Infection With Low-Dose #Glucocorticoids in Patients With #Rheumatoid Arthritis
The unfolding #COVID-19 pandemic: A probability-based, nationally representative study of #mental health in the U.S.
The COVID-19 pandemic is a collective stressor unfolding over time, yet rigorous published empirical studies addressing mental health consequences of COVID-19 among large probability-based national samples are rare. Between 3/18-4/18/20, during an escalating period of illness and death in the United States, we assessed acute stress, depressive symptoms and direct, community, and media-based exposures to… Continue reading The unfolding #COVID-19 pandemic: A probability-based, nationally representative study of #mental health in the U.S.
Chest x-ray findings and temporal #lung changes in patients with #COVID-19 pneumonia
Chest CT scan and chest x-rays show characteristic radiographic findings in patients with COVID-19 pneumonia. Chest x-ray can be used in diagnosis and follow up in patients with COVID-19 pneumonia. The study aims at describing the chest x-ray findings and temporal radiographic changes in COVID-19 patients.. ..A total of 88 patients (50 (56.8%) females and… Continue reading Chest x-ray findings and temporal #lung changes in patients with #COVID-19 pneumonia
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