Background: Prediabetes is on the rise and can progress to type 2 diabetes and related cardiometabolic complications if left untreated. Nutrition plays a critical role in blood glucose regulation, and evaluating the effects of whole foods on indices of glycemic control and body composition within individuals with prediabetes is important. This study examined whether consuming… Continue reading Daily #Mango Intake Improves #Glycemic and Body Composition Outcomes in Adults with #Prediabetes: A Randomized Controlled Study
Category: Endocrinology
Effect of #Metformin on the Risk of Post- #coronavirus Disease 2019 Condition Among Individuals With #Overweight or #Obese: A Population-based Retrospective Cohort Study
BackgroundA subgroup analysis of the COVID-OUT trial's long-term outcome found that starting metformin within 3 days of coronavirus disease 2019 (COVID-19) diagnosis reduced post–COVID-19 condition (PCC) incidence by 63% in overweight or obese individuals. However, its generalizability remains uncertain.ObjectivesTo evaluate the effectiveness of metformin in preventing PCC in adults with overweight or obesity who had… Continue reading Effect of #Metformin on the Risk of Post- #coronavirus Disease 2019 Condition Among Individuals With #Overweight or #Obese: A Population-based Retrospective Cohort Study
Serum microRNA analysis facilitates decision-making between active surveillance and immediate surgery for low-risk #thyroid #tumors
Objective: To develop a practical and cost-effective test to distinguish patients with malignant thyroid nodules eligible for active surveillance from those requiring immediate surgery.Methods: This prospective observational study included patients with malignant thyroid nodules (3 to 15 mm) who were assigned to either an Active Surveillance Group (n = 30) or a Surgery Group (n… Continue reading Serum microRNA analysis facilitates decision-making between active surveillance and immediate surgery for low-risk #thyroid #tumors
Total and specific #potato intake and risk of type 2 #diabetes: results from three US cohort studies and a substitution meta-analysis of prospective cohorts
Objectives To investigate the associations between total and individual potato intake and risk of type 2 diabetes (T2D), estimate the effect on T2D risk of replacing potatoes with whole grains and other major carbohydrate sources, and conduct a dose-response and substitution meta-analysis of prospective cohort studies.Design Prospective cohort study and dose-response meta-analysis of prospective cohort… Continue reading Total and specific #potato intake and risk of type 2 #diabetes: results from three US cohort studies and a substitution meta-analysis of prospective cohorts
Exposure to per- and poly-fluoroalkyl substances in association to later occurrence of type 2 #diabetes and metabolic pathway #dysregulation in a multiethnic US population
Growing evidence suggests that exposure to per- and polyfluoroalkyl substances ( #PFAS ) are linked to an increased risk of type 2 diabetes (T2D); however, the effect of PFAS mixtures and underlying mechanisms are not well understood. We examined the associations between exposure to PFAS mixture with later T2D diagnosis and underlying metabolic dysregulations.MethodsWe conducted… Continue reading Exposure to per- and poly-fluoroalkyl substances in association to later occurrence of type 2 #diabetes and metabolic pathway #dysregulation in a multiethnic US population
Association of #Weekend #Warrior and Other Physical #Activity Patterns With #Mortality Among Adults With #Diabetes: A Cohort Study
Background:“Weekend warrior” and regularly active physical activity patterns have been associated with reduced mortality risk in the general population. The association in patients with diabetes is unknown.Objective:To examine the associations of different physical activity patterns, particularly weekend warrior and regularly active behavior, with all-cause, cardiovascular, and cancer mortality among adults with diabetes.Design:Prospective cohort study.Setting:National Health… Continue reading Association of #Weekend #Warrior and Other Physical #Activity Patterns With #Mortality Among Adults With #Diabetes: A Cohort Study
Body #mass index and #breast cancer risk among #postmenopausal women with and without cardiometabolic diseases: Findings from two prospective cohort studies in Europe
BackgroundAdiposity, measured by body mass index (BMI), is a known risk factor for postmenopausal breast cancer. However, whether the association of BMI with breast cancer risk differs among women with and without cardiovascular diseases (CVDs) or type 2 diabetes (T2D) is uncertain.MethodsThis study used individual participant data from the European Prospective Investigation into Cancer and… Continue reading Body #mass index and #breast cancer risk among #postmenopausal women with and without cardiometabolic diseases: Findings from two prospective cohort studies in Europe
Later #eating #timing in relation to an individual internal clock is associated with lower #insulin sensitivity and affected by genetic factors
BackgroundAlthough the contribution of the circadian clock to metabolic regulation is widely recognized, the role of eating timing in glucose metabolism and diabetes risk remains insufficiently studied. This study aimed (i) to investigate the link between the eating timing pattern relative to individual clock and glucose homoeostasis and (ii) to explore the contribution of genetic… Continue reading Later #eating #timing in relation to an individual internal clock is associated with lower #insulin sensitivity and affected by genetic factors
Emerging and accumulating safety signals for the use of #estrogen among #transgender women
Efforts to alleviate the psychological distress of gender dysphoria have included the use of exogenous estrogen (often with anti-androgens) to alter secondary sex characteristics of natal males. In response to the rapid increase in presenting cases among young people, extensive scrutiny has now been brought to bear on these medical interventions for minors, with ESCAP… Continue reading Emerging and accumulating safety signals for the use of #estrogen among #transgender women
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