The rising prevalence of prediabetes has increased the risk of diabetes, particularly among younger populations, if timely interventions are not implemented. In India, the limited availability of cohort-based incidence studies underscores the need for retrospective analyses using hospital-based electronic medical information systems (EMIS). This study estimates the transition probabilities and duration of stay in the… Continue reading Transition between #prediabetic and #diabetic stages in an urban community in india: a decade-long retrospective cohort study
Category: Endocrinology
A six-year longitudinal study identifies a #statin -independent association between low LDL- #cholesterol and risk of type 2 #diabetes
Statin therapy has been associated with increased risk of type 2 diabetes (T2D). We investigated the relationship between Low-Density Lipoprotein Cholesterol (LDL-C) plasma concentrations and incident T2D and evaluated the modifying effect of statin therapy in a large population-based cohort.MethodsIndividuals free of T2D and cardiovascular disease at baseline were followed longitudinally for the development of… Continue reading A six-year longitudinal study identifies a #statin -independent association between low LDL- #cholesterol and risk of type 2 #diabetes
#Electroacupuncture modulates myocardial insulin signaling and inflammatory markers in a rat model of type 2 #diabetes
Objective: To evaluate the effects of electroacupuncture (EA) on myocardial insulin resistance (IR) in Zucker diabetic fatty (ZDF) rats, an established model for type 2 diabetes mellitus (T2DM).Methods: Twenty-four ZDF-Leprfa/fa rats were randomized to: (1) ZDF group (n = 8); (2) ZDF + PIO (pioglitazone) group (n = 8); and (3) ZDF + EA group… Continue reading #Electroacupuncture modulates myocardial insulin signaling and inflammatory markers in a rat model of type 2 #diabetes
Treatment patterns of #romosozumab in postmenopausal women with severe #osteoporosis in Denmark: findings from the ROmosozumab in Scandinavia real-world Evidence Study (ROSES)
To describe patient and prescriber characteristics and factors associated with utilization of romosozumab in Denmark.MethodsThis registry‑based Danish retrospective cohort study comprised females aged ≥ 50 receiving osteoporosis medication from September 2020 − October 2023. Three cohorts were identified: those treated with romosozumab (cohort 1), those with osteoporosis‑related fracture within the last three years treated with other osteoporosis medications (cohort… Continue reading Treatment patterns of #romosozumab in postmenopausal women with severe #osteoporosis in Denmark: findings from the ROmosozumab in Scandinavia real-world Evidence Study (ROSES)
Association Between Wake-Time #Movement Behaviors and #Weight Loss Maintenance
We examined whether wake-time movement composition was associated with weight loss maintenance among individuals who experienced clinically meaningful weight loss (> 5% of initial weight) using compositional data analysis.MethodsThis was a secondary analysis from a behavioral weight loss maintenance intervention on weight regain over 12 months following clinically meaningful 3-month weight loss. Body weight was assessed… Continue reading Association Between Wake-Time #Movement Behaviors and #Weight Loss Maintenance
Daily #Mango Intake Improves #Glycemic and Body Composition Outcomes in Adults with #Prediabetes: A Randomized Controlled Study
Background: Prediabetes is on the rise and can progress to type 2 diabetes and related cardiometabolic complications if left untreated. Nutrition plays a critical role in blood glucose regulation, and evaluating the effects of whole foods on indices of glycemic control and body composition within individuals with prediabetes is important. This study examined whether consuming… Continue reading Daily #Mango Intake Improves #Glycemic and Body Composition Outcomes in Adults with #Prediabetes: A Randomized Controlled Study
Effect of #Metformin on the Risk of Post- #coronavirus Disease 2019 Condition Among Individuals With #Overweight or #Obese: A Population-based Retrospective Cohort Study
BackgroundA subgroup analysis of the COVID-OUT trial's long-term outcome found that starting metformin within 3 days of coronavirus disease 2019 (COVID-19) diagnosis reduced post–COVID-19 condition (PCC) incidence by 63% in overweight or obese individuals. However, its generalizability remains uncertain.ObjectivesTo evaluate the effectiveness of metformin in preventing PCC in adults with overweight or obesity who had… Continue reading Effect of #Metformin on the Risk of Post- #coronavirus Disease 2019 Condition Among Individuals With #Overweight or #Obese: A Population-based Retrospective Cohort Study
Serum microRNA analysis facilitates decision-making between active surveillance and immediate surgery for low-risk #thyroid #tumors
Objective: To develop a practical and cost-effective test to distinguish patients with malignant thyroid nodules eligible for active surveillance from those requiring immediate surgery.Methods: This prospective observational study included patients with malignant thyroid nodules (3 to 15 mm) who were assigned to either an Active Surveillance Group (n = 30) or a Surgery Group (n… Continue reading Serum microRNA analysis facilitates decision-making between active surveillance and immediate surgery for low-risk #thyroid #tumors
Total and specific #potato intake and risk of type 2 #diabetes: results from three US cohort studies and a substitution meta-analysis of prospective cohorts
Objectives To investigate the associations between total and individual potato intake and risk of type 2 diabetes (T2D), estimate the effect on T2D risk of replacing potatoes with whole grains and other major carbohydrate sources, and conduct a dose-response and substitution meta-analysis of prospective cohort studies.Design Prospective cohort study and dose-response meta-analysis of prospective cohort… Continue reading Total and specific #potato intake and risk of type 2 #diabetes: results from three US cohort studies and a substitution meta-analysis of prospective cohorts
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