The Effects of the #Mediterranean Diet on #Health and Gut #Microbiota

The Mediterranean Diet (MD) is plant-based and consists of multiple daily portions of vegetables, fruit, cereals, and olive oil. Although there are challenges with isolating the MD from the typical Mediterranean lifestyle and culture (including prolonged ‘social’ meals and siestas), much evidence supports the health benefits of the MD that include improved longevity, reduced metabolic… Continue reading The Effects of the #Mediterranean Diet on #Health and Gut #Microbiota

Total and specific #potato intake and risk of type 2 #diabetes: results from three US cohort studies and a substitution meta-analysis of prospective cohorts

Objectives To investigate the associations between total and individual potato intake and risk of type 2 diabetes (T2D), estimate the effect on T2D risk of replacing potatoes with whole grains and other major carbohydrate sources, and conduct a dose-response and substitution meta-analysis of prospective cohort studies.Design Prospective cohort study and dose-response meta-analysis of prospective cohort… Continue reading Total and specific #potato intake and risk of type 2 #diabetes: results from three US cohort studies and a substitution meta-analysis of prospective cohorts

#Dietary patterns and accelerated multimorbidity in #older adults

Diet could influence disease development and shape multimorbidity trajectories. Here we examined how four dietary patterns relate to 15-year multimorbidity accumulation in 2,473 community-dwelling older adults from the Swedish SNAC-K cohort. Multimorbidity was operationalized as the total number of chronic conditions and grouped into three organ systems. Higher adherence to the Mediterranean-DASH Diet Intervention for… Continue reading #Dietary patterns and accelerated multimorbidity in #older adults

#Sucralose consumption ablates #cancer immunotherapy response through #microbiome disruption

Gut microbiota composition is directly associated with response to immunotherapies in cancer. How the diet impacts the gut microbiota and downstream immune responses to cancer remains unclear. Here, we show that consumption of a common non-nutritive sweetener, sucralose, modifies microbiome composition, restricts T cell metabolism and function, and limits immunotherapy response in preclinical models of… Continue reading #Sucralose consumption ablates #cancer immunotherapy response through #microbiome disruption

Association between ultra-processed #food consumption and #lung #cancer risk: a population-based cohort study

Background The evidence on associations between ultra-processed foods (UPF) and lung cancer risk is limited and inconsistent.Research question Are UPF associated with an increased risk of lung cancer, non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC)?Methods Data of participants in this study were collected from the Prostate, Lung, Colorectal and Ovarian (PLCO)… Continue reading Association between ultra-processed #food consumption and #lung #cancer risk: a population-based cohort study

Association of #Egg Intake With #Alzheimer’s #Dementia Risk in #Older Adults: The Rush #Memory and Aging Project

BackgroundAlzheimer’s disease (AD) is a neurodegenerative disorder with increasing prevalence due to population aging. Eggs provide many nutrients important for brain health, including choline, omega-3 fatty acids, and lutein. Emerging evidence suggests that frequent egg consumption may improve cognitive performance on verbal tests, but whether consumption influences the risk of Alzheimer’s dementia and AD is… Continue reading Association of #Egg Intake With #Alzheimer’s #Dementia Risk in #Older Adults: The Rush #Memory and Aging Project

Association between dietary #copper intake and #cognitive function in American older adults: NHANES 2011–2014

This cross-sectional observational study examined the association between dietary copper intake and cognitive function in American older adults, using data from the 2011 to 2014 National Health and Nutrition Examination Survey (NHANES). Analyzing a total of 2420 participants, dietary copper intake was determined by averaging two 24-h dietary recalls, whereas cognitive function was assessed by… Continue reading Association between dietary #copper intake and #cognitive function in American older adults: NHANES 2011–2014

Later #eating #timing in relation to an individual internal clock is associated with lower #insulin sensitivity and affected by genetic factors

BackgroundAlthough the contribution of the circadian clock to metabolic regulation is widely recognized, the role of eating timing in glucose metabolism and diabetes risk remains insufficiently studied. This study aimed (i) to investigate the link between the eating timing pattern relative to individual clock and glucose homoeostasis and (ii) to explore the contribution of genetic… Continue reading Later #eating #timing in relation to an individual internal clock is associated with lower #insulin sensitivity and affected by genetic factors

Health effects associated with consumption of processed #meat, #sugar -sweetened beverages and trans fatty acids: a Burden of Proof study

Previous research suggests detrimental health effects associated with consuming processed foods, including processed meats, sugar-sweetened beverages (SSBs) and trans fatty acids (TFAs). However, systematic characterization of the dose–response relationships between these foods and health outcomes is limited. Here, using Burden of Proof meta-regression methods, we evaluated the associations between processed meat, SSBs and TFAs and… Continue reading Health effects associated with consumption of processed #meat, #sugar -sweetened beverages and trans fatty acids: a Burden of Proof study