Association between dietary #copper intake and #cognitive function in American older adults: NHANES 2011–2014

This cross-sectional observational study examined the association between dietary copper intake and cognitive function in American older adults, using data from the 2011 to 2014 National Health and Nutrition Examination Survey (NHANES). Analyzing a total of 2420 participants, dietary copper intake was determined by averaging two 24-h dietary recalls, whereas cognitive function was assessed by… Continue reading Association between dietary #copper intake and #cognitive function in American older adults: NHANES 2011–2014

Later #eating #timing in relation to an individual internal clock is associated with lower #insulin sensitivity and affected by genetic factors

BackgroundAlthough the contribution of the circadian clock to metabolic regulation is widely recognized, the role of eating timing in glucose metabolism and diabetes risk remains insufficiently studied. This study aimed (i) to investigate the link between the eating timing pattern relative to individual clock and glucose homoeostasis and (ii) to explore the contribution of genetic… Continue reading Later #eating #timing in relation to an individual internal clock is associated with lower #insulin sensitivity and affected by genetic factors

Health effects associated with consumption of processed #meat, #sugar -sweetened beverages and trans fatty acids: a Burden of Proof study

Previous research suggests detrimental health effects associated with consuming processed foods, including processed meats, sugar-sweetened beverages (SSBs) and trans fatty acids (TFAs). However, systematic characterization of the dose–response relationships between these foods and health outcomes is limited. Here, using Burden of Proof meta-regression methods, we evaluated the associations between processed meat, SSBs and TFAs and… Continue reading Health effects associated with consumption of processed #meat, #sugar -sweetened beverages and trans fatty acids: a Burden of Proof study

Health effects associated with consumption of #processed #meat, #sugar -sweetened beverages and trans #fatty acids: a Burden of Proof study

Previous research suggests detrimental health effects associated with consuming processed foods, including processed meats, sugar-sweetened beverages (SSBs) and trans fatty acids (TFAs). However, systematic characterization of the dose–response relationships between these foods and health outcomes is limited. Here, using Burden of Proof meta-regression methods, we evaluated the associations between processed meat, SSBs and TFAs and… Continue reading Health effects associated with consumption of #processed #meat, #sugar -sweetened beverages and trans #fatty acids: a Burden of Proof study

The relationship between #polyunsaturated #fatty acids and #inflammation: evidence from cohort and Mendelian randomization analyses

Omega-3 (n-3) and omega-6 (n-6) polyunsaturated fatty acids (PUFAs) are thought to have anti- and pro-inflammatory roles, respectively, and influence the risk of various chronic diseases. However, it is unclear whether these associations are causal.MethodsWe examined the associations of dietary polyunsaturated FAs with biomarkers of systemic inflammation: C-reactive protein (CRP), glycoprotein acetyls (GlycA), and interleukin… Continue reading The relationship between #polyunsaturated #fatty acids and #inflammation: evidence from cohort and Mendelian randomization analyses

Genetic Correlation and Mendelian Randomization Analyses Support Causal Relationships Between Instant #Coffee and Age-Related #Macular Degeneration

Coffee is a popular beverage, and previous cohort studies suggest it may reduce the risk of age-related macular degeneration (AMD). However, confounding factors in these studies necessitate further exploration of causal relationships using advanced methods. We obtained data on coffee consumption from genome-wide association studies (GWAS) and the latest AMD-related GWAS summary data from the… Continue reading Genetic Correlation and Mendelian Randomization Analyses Support Causal Relationships Between Instant #Coffee and Age-Related #Macular Degeneration

#Rapamycin, Not #Metformin, Mirrors #Dietary Restriction-Driven #Lifespan Extension in Vertebrates: A Meta-Analysis

Dietary restriction (DR) robustly increases lifespan across taxa. However, in humans, long-term DR is difficult to maintain, leading to the search for compounds that regulate metabolism and increase lifespan without reducing caloric intake. The magnitude of lifespan extension from two such compounds, rapamycin and metformin, remains inconclusive, particularly in vertebrates. Here, we conducted a meta-analysis… Continue reading #Rapamycin, Not #Metformin, Mirrors #Dietary Restriction-Driven #Lifespan Extension in Vertebrates: A Meta-Analysis

Association of #plant -based diets with subclinical #cardiovascular disease in U.S. adults, 1999-2004

BackgroundDietary patterns currently recommended for cardiovascular health often emphasize the consumption of plant foods.MethodsWe included 7,708 participants from the National Health and Nutrition Examination Survey 1999-2004 aged ≥20 years who were not pregnant and did not have a self-reported history of cardiovascular disease. Dietary intake was assessed using a 24-hour dietary recall. All plant-based dietary… Continue reading Association of #plant -based diets with subclinical #cardiovascular disease in U.S. adults, 1999-2004

Short-Term Cardiometabolic Response to #Mango Intake in Post #menopausal #Women

Consumption of mangos has been associated with improved diet quality, with reported reductions in systolic blood pressure and inflammatory biomarkers when consumed daily in robust amounts for six to eight weeks. Whether these changes could occur with a shorter intake period is unknown.MethodsThis study explored the effect of two weeks of mango intake (330 g/d) on… Continue reading Short-Term Cardiometabolic Response to #Mango Intake in Post #menopausal #Women