Background: Older adults account for an increasing proportion of emergency department visits for mild traumatic brain injury (mTBI). Although age is incorporated as a high-risk criterion in major clinical decision rules, the operational impact of risk stratification on computed tomography (CT) utilization in very elderly patients remains uncertain.Methods: We conducted a retrospective cohort study including… Continue reading Limited clinical utility of risk stratification for CT decision-making in patients ≥ 75 years with mild traumatic brain injury
Author: aledopress
Medicine and Technology enthusiast..
Beyond conventional lipid markers: Atherogenic index of plasma and triglyceride-glucose index in relation to cardiometabolic multimorbidity in older adults
Purpose: This study aimed to compare the associations and predictive performance of atherogenic index of plasma (AIP) and the triglyceride-glucose (TyG) index for incident cardiometabolic multimorbidity (CMM).Methods: Data was analyzed from 2261 adults (mean age 63 years; 45.0% men) in the English Longitudinal Study of Ageing without a history of cardiometabolic disease at baseline (2008-2009).… Continue reading Beyond conventional lipid markers: Atherogenic index of plasma and triglyceride-glucose index in relation to cardiometabolic multimorbidity in older adults
Korean Clinical Practice Guidelines for Interstitial Lung Disease: Part 2. Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrosing interstitial pneumonia characterized by declining lung function, severe dyspnea, and a poor prognosis. Although antifibrotic agents have improved outcomes in patients with IPF, important challenges remain in the diagnosis, monitoring, and long-term management of the disease. Since the publication of the first Korean clinical practice guideline… Continue reading Korean Clinical Practice Guidelines for Interstitial Lung Disease: Part 2. Idiopathic Pulmonary Fibrosis
Explainable Machine Learning for Predicting Deep Vein Thrombosis in Critically Ill Patients with COPD: Development and Multicenter External Validation
Background: Deep vein thrombosis (DVT) is a frequent yet underrecognized complication in critically ill patients with chronic obstructive pulmonary disease (COPD). Existing risk assessment tools are not specifically tailored to this high-risk population. We aimed to develop and externally validate an interpretable machine-learning model for early prediction of DVT in ICU-admitted COPD patients.Methods: Adult COPD… Continue reading Explainable Machine Learning for Predicting Deep Vein Thrombosis in Critically Ill Patients with COPD: Development and Multicenter External Validation
Impact of Pre-injury Statin Use on Mortality and Short-Term Clinical Outcomes Following Intracerebral Hemorrhage: A Propensity-Matched Cohort Study
Background Intracerebral hemorrhage (ICH) is associated with high mortality and limited therapeutic options. The impact of statin therapy on outcomes following ICH remains controversial. Methods A retrospective cohort study was conducted using the TriNetX Global Collaborative Network. Adult patients (≥18 years) with nontraumatic ICH were identified and stratified based on statin use within three months… Continue reading Impact of Pre-injury Statin Use on Mortality and Short-Term Clinical Outcomes Following Intracerebral Hemorrhage: A Propensity-Matched Cohort Study
Assessing noise perceptions in Italian adolescents: validation of the Italian youth attitude to noise scale (YANS-it)
Objective: To translate, culturally adapt, and validate the Italian version of the Youth Attitude to Noise Scale (YANS-It) and to assess Italian adolescents' attitudes towards noise exposure.Design: Cross-cultural adaptation and validation study using forward-backward translation and pilot testing, followed by a nationwide online cross-sectional survey. Psychometric analysis included Confirmatory Factor Analysis with the WLSMV estimator,… Continue reading Assessing noise perceptions in Italian adolescents: validation of the Italian youth attitude to noise scale (YANS-it)
Long-term impact of acute pancreatitis on patients’ quality of life: a multi-center prospective study in Japan
Background: Although acute pancreatitis often resolves, its long-term impact on health-related quality of life (HRQoL) and social participation remains unclear. This study investigated the longitudinal changes in HRQoL and factors affecting incomplete recovery of social participation following acute pancreatitis.Methods: This multi-center, prospective cohort study included patients aged ≥ 18 years who were hospitalized with acute… Continue reading Long-term impact of acute pancreatitis on patients’ quality of life: a multi-center prospective study in Japan
The gut microbiome in chemotherapy-induced fatigue: Exploring clinical associations and modulation via fecal microbiota transplantation in female mice
Background: Fatigue is a common and debilitating side effect of chemotherapy, negatively affecting treatment adherence and survival. Chemotherapy alters gut microbiome composition, and accumulating evidence suggests that gut microbes contribute to chemotherapy-induced fatigue. Because the gut microbiome is modifiable through targeted interventions, such as fecal microbiota transplantation (FMT), microbiome modulation has emerged as a potential… Continue reading The gut microbiome in chemotherapy-induced fatigue: Exploring clinical associations and modulation via fecal microbiota transplantation in female mice
Extending the Fear-Avoidance Model of pain to youth: Psychometric evaluation of the 11-item Tampa Scale of Kinesiophobia in children and adolescents
Kinesiophobia plays a central role in understanding adult pain mechanisms, yet its assessment and theoretical relevance in pediatric pain remain poorly understood. Research to clarify the role of kinesiophobia in pediatric populations requires a valid and reliable measure of the construct. The most commonly used measure is the Tampa Scale of Kinesiophobia (TSK). Unfortunately, prior… Continue reading Extending the Fear-Avoidance Model of pain to youth: Psychometric evaluation of the 11-item Tampa Scale of Kinesiophobia in children and adolescents
2 Medical News 