Association of Eating and Sleeping Intervals With Weight Change Over Time: The Daily24 Cohort

BackgroundWe aim to evaluate the association between meal intervals and weight trajectory among adults from a clinical cohort.Methods and ResultsThis is a multisite prospective cohort study of adults recruited from 3 health systems. Over the 6‐month study period, 547 participants downloaded and used a mobile application to record the timing of meals and sleep for …

Continue reading Association of Eating and Sleeping Intervals With Weight Change Over Time: The Daily24 Cohort

Increased Intake of Both Caffeine and Non-Caffeine Coffee Components Is Associated with Reduced NAFLD Severity in Subjects with Type 2 Diabetes

Coffee may protect against non-alcoholic fatty liver disease (NAFLD), but the roles of the caffeine and non-caffeine components are unclear. Coffee intake by 156 overweight subjects (87% with Type-2-Diabetes, T2D) was assessed via a questionnaire, with 98 subjects (all T2D) also providing a 24 h urine sample for quantification of coffee metabolites by LC–MS/MS. NAFLD …

Continue reading Increased Intake of Both Caffeine and Non-Caffeine Coffee Components Is Associated with Reduced NAFLD Severity in Subjects with Type 2 Diabetes

Social isolation and 9-year dementia risk in community-dwelling Medicare beneficiaries in the United States

BackgroundSocial isolation can influence whether older adults develop dementia. We examine the association between social isolation and incident dementia among older adults in a nationally representative sample of community dwelling older adults in the United States (U.S.). We also investigate whether this association varies by race and ethnicity.MethodsData (N = 5022) come from the National Health and …

Continue reading Social isolation and 9-year dementia risk in community-dwelling Medicare beneficiaries in the United States

Dietary exposure to nitrites and nitrates in association with type 2 diabetes risk: Results from the NutriNet-Santé population-based cohort study

Nitrites and nitrates occur naturally in water and soil and are commonly ingested from drinking water and dietary sources. They are also used as food additives, mainly in processed meats, to increase shelf life and to avoid bacterial growth. Experimental studies suggested both benefits and harmful effects of nitrites and nitrates exposure on type 2 …

Continue reading Dietary exposure to nitrites and nitrates in association with type 2 diabetes risk: Results from the NutriNet-Santé population-based cohort study

Guidelines of care for the management of atopic dermatitis in adults with topical therapies

BackgroundNew evidence has emerged since the 2014 guidelines that further informs the management of AD with topical therapies. These guidelines update the 2014 recommendations for management of atopic dermatitis (AD) with topical therapies.ObjectiveTo provide evidence-based recommendations related to management of AD in adults using topical treatments.MethodsA multidisciplinary workgroup conducted a systematic review and applied the …

Continue reading Guidelines of care for the management of atopic dermatitis in adults with topical therapies