Background/Objectives: Depression is a major global health burden, and previous studies suggest that nutrient deficiencies may contribute to its development. However, research on mineral intake and depression, particularly sodium and potassium, is limited. We conducted a cross-sectional analysis of data from the National Health and Nutrition Examination Survey in Korea (KNHANES) and the United States… Continue reading #Mineral Intake and #Depression: A Cross-Sectional Comparative Study Based on National Health and Nutrition Examination Surveys in Korea and the United States
Tag: zinc
Human #cells experience a #Zn2+ pulse in early G1
Highlights•Human cells experience a transient zinc pulse in early G1•The magnitude of the pulse tracks with the amount of zinc in the cytosol and media•Knockdown of MTF-1 decreases metallothionein and increases the zinc pulse•Cells pause proliferation until labile cellular zinc is in the optimum range SummaryZinc is an essential micronutrient required for all domains of… Continue reading Human #cells experience a #Zn2+ pulse in early G1
Associations of serum zinc, copper, and selenium with sleep disorders in the American adults: Data from NHANES 2011–2016
BackgroundEven though various studies have been conducted to investigate the relationship between trace metals and sleep, few epidemiological studies have evaluated the relationship between trace metals and sleep disorders in American adults.ObjectiveThis study intended to evaluate the associations of serum zinc (Zn), copper (Cu), selenium (Se), Zn/Cu, Zn/Se, and Cu/Se ratios with sleep disorders in… Continue reading Associations of serum zinc, copper, and selenium with sleep disorders in the American adults: Data from NHANES 2011–2016
Zinc ions prevent α-synuclein aggregation by enhancing chaperone function of human serum albumin
Metal ions present in cellular microenvironment have been implicated as drivers of aggregation of amyloid forming proteins. Zinc (Zn2+) ions have been reported to directly interact with α-synuclein (AS), a causative agent of Parkinson's disease and other neurodegenerative diseases, and promote its aggregation. AS is a small intrinsically disordered protein (IDP) i.e., understanding molecular factors… Continue reading Zinc ions prevent α-synuclein aggregation by enhancing chaperone function of human serum albumin
Therapies to Prevent Progression of COVID-19, Including Hydroxychloroquine, Azithromycin, Zinc, and Vitamin D3 With or Without Intravenous Vitamin C: An International, Multicenter, Randomized Trial
Therapies to Prevent Progression of COVID-19, Including Hydroxychloroquine, Azithromycin, Zinc, and Vitamin D3 With or Without Intravenous Vitamin C: An International, Multicenter, Randomized TrialKarin Ried, Taufiq BinJemain, Avni Sali Published: November 25, 2021 (see history) DOI: 10.7759/cureus.19902 Cite this article as: Ried K, BinJemain T, Sali A (November 25, 2021) Therapies to Prevent Progression of… Continue reading Therapies to Prevent Progression of COVID-19, Including Hydroxychloroquine, Azithromycin, Zinc, and Vitamin D3 With or Without Intravenous Vitamin C: An International, Multicenter, Randomized Trial
#Zinc for the prevention or treatment of acute viral #respiratory tract infections in adults: a rapid systematic review and meta-analysis of randomised controlled trials
To evaluate the benefits and risks of zinc formulations compared with controls for prevention or treatment of acute viral respiratory tract infections (RTIs) in adults. Method Seventeen English and Chinese databases were searched in April/May 2020 for randomised controlled trials (RCTs), and from April/May 2020 to August 2020 for SARS-CoV-2 RCTs. Cochrane rapid review methods… Continue reading #Zinc for the prevention or treatment of acute viral #respiratory tract infections in adults: a rapid systematic review and meta-analysis of randomised controlled trials
#Zinc, Vitamin D and Vitamin C: Perspectives for #COVID-19 With a Focus on Physical Tissue Barrier Integrity
Some nutrients play key roles in maintaining the integrity and function of the immune system, presenting synergistic actions in steps determinant for the immune response. Among these elements, zinc and vitamins C and D stand out for having immunomodulatory functions and for playing roles in preserving physical tissue barriers. Considering the COVID-19 pandemic, nutrients that… Continue reading #Zinc, Vitamin D and Vitamin C: Perspectives for #COVID-19 With a Focus on Physical Tissue Barrier Integrity
#Zinc drives #vasorelaxation by acting in sensory nerves, endothelium and smooth muscle
Zinc, an abundant transition metal, serves as a signalling molecule in several biological systems. Zinc transporters are genetically associated with cardiovascular diseases but the function of zinc in vascular tone regulation is unknown. We found that elevating cytoplasmic zinc using ionophores relaxed rat and human isolated blood vessels and caused hyperpolarization of smooth muscle membrane.… Continue reading #Zinc drives #vasorelaxation by acting in sensory nerves, endothelium and smooth muscle
Low #Zinc Levels at Admission Associates with Poor Clinical Outcomes in #SARS-CoV-2 Infection
Background: Zinc is an essential micronutrient that impacts host–pathogen interplay at infection. Zinc balances immune responses, and also has a proven direct antiviral action against some viruses. Importantly, zinc deficiency (ZD) is a common condition in elderly and individuals with chronic diseases, two groups with an increased risk for severe severe coronavirus disease 2019 (COVID-19)… Continue reading Low #Zinc Levels at Admission Associates with Poor Clinical Outcomes in #SARS-CoV-2 Infection
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