The effect of #depression status change on daily #cigarette smoking amount according to sex: an eleven-year follow up study of the Korea Welfare Panel Study

In the past decade, the Korean smoking rate has only decreased by 3%, despite several smoking control policies. There is a need for such policies to take smokers’ psychological characteristics into account. Depression is a well-known contributor to failed smoking cessation. This study aimed to examine the effect of smokers’ depression status changes on their… Continue reading The effect of #depression status change on daily #cigarette smoking amount according to sex: an eleven-year follow up study of the Korea Welfare Panel Study

#Social Health and #Cardiovascular Disease Risk Factors: A cross-sectional study in a healthy older adult population

Poor social health is a risk factor for cardiovascular disease (CVD), however an in-depth exploration of the link through CVD risk factors is lacking. AimTo examine the relationship between social health (social isolation, social support, loneliness) and CVD risk factors among healthy older women and men. MethodsData were from 11,498 healthy community-dwelling Australians aged ≥70… Continue reading #Social Health and #Cardiovascular Disease Risk Factors: A cross-sectional study in a healthy older adult population

A phase 2 trial of inhaled #nitrous oxide for treatment-resistant major #depression

Laughing gas improves depressionAbout one-third of individuals suffering from depression are at risk for treatment resistance. Whereas inhaled 50% nitrous oxide has early antidepressant effects on individuals with treatment-resistant major depression (TRMD), adverse effects can occur at this concentration. In this phase 2 clinical trial, Nagele et al. studied the effects of a single 1-hour… Continue reading A phase 2 trial of inhaled #nitrous oxide for treatment-resistant major #depression

Reduced adaptation of glutamatergic #stress response is associated with #pessimistic expectations in #depression

Stress is a significant risk factor for the development of major depressive disorder (MDD), yet the underlying mechanisms remain unclear. Preclinically, adaptive and maladaptive stress-induced changes in glutamatergic function have been observed in the medial prefrontal cortex (mPFC). Here, we examine stress-induced changes in human mPFC glutamate using magnetic resonance spectroscopy (MRS) in two healthy… Continue reading Reduced adaptation of glutamatergic #stress response is associated with #pessimistic expectations in #depression

Sex differences in risk factors for #depressive symptoms in patients with #COPD: The 2014 and 2016 Korea National Health and Nutrition Examination Survey

Although depression is a common comorbidity of chronic obstructive pulmonary disease (COPD), the role of sex remains unexplored. We evaluated sex differences of risk factors of depressive symptoms in adults with COPD. MethodsThis was a population-based cross-sectional study using data from the 2014 and 2016 Korea National Health and Nutrition Examination Survey. Spirometry was used… Continue reading Sex differences in risk factors for #depressive symptoms in patients with #COPD: The 2014 and 2016 Korea National Health and Nutrition Examination Survey

Association of #Depressive Symptoms with Rapid #Kidney Function Decline in Adults with Normal Kidney Function

The relationship of depressive symptoms with kidney function remains poorly investigated. We aimed to evaluate the prospective association between depressive symptoms and rapid decline in kidney function in Chinese adults with normal kidney function. Design, setting, participants, & measurements A total of 4763 participants with eGFR≥60 ml/min per 1.73 m2 at baseline were enrolled from… Continue reading Association of #Depressive Symptoms with Rapid #Kidney Function Decline in Adults with Normal Kidney Function

Genetically Proxied Diurnal Preference, #Sleep Timing, and Risk of Major #Depressive Disorder

Morning diurnal preference is associated with reduced risk of major depressive disorder (MDD); however, causality in this association is uncertain. Objective To examine the association of genetically proxied morning diurnal preference with depression risk using mendelian randomization. Design, Setting, and Participants This 2-sample mendelian randomization study used summary-level genetic associations with diurnal preference and MDD.… Continue reading Genetically Proxied Diurnal Preference, #Sleep Timing, and Risk of Major #Depressive Disorder

Dynamic Associations Between #Anxiety, #Depression, and #Tobacco Use in Older Adults: Results From The Irish Longitudinal Study on Ageing

Evidence supports moderate-to-large reductions in anxiety, depression, and perceived stress after smoking cessation; however, much of the available evidence has focused on young adults. Therefore, this study quantified associations between smoking and smoking cessation on prevalent and incident generalised anxiety disorder (GAD) and major depression (MDD) in a nationally representative sample of Irish older adults.… Continue reading Dynamic Associations Between #Anxiety, #Depression, and #Tobacco Use in Older Adults: Results From The Irish Longitudinal Study on Ageing

Clinical outcomes in a large registry of patients with major #depressive disorder treated with Transcranial #Magnetic Stimulation

Clinical outcomes were examined in the largest registry of patients treated for an episode of major depressive disorder. •The registry included more than more than 5,000 patients treated with TMS at more than 100 private practice sites. •Self-report and clinician ratings showed robust antidepressant effects, greater than those in the early studies of TMS. •Efficacy… Continue reading Clinical outcomes in a large registry of patients with major #depressive disorder treated with Transcranial #Magnetic Stimulation