Long #Working Hours and the Prevalence of Masked and Sustained #Hypertension

Previous studies on the effect of long working hours on blood pressure have shown inconsistent results. Mixed findings could be attributable to limitations related to blood pressure measurement and the lack of consideration of masked hypertension.. Ambulatory blood pressure was defined as the mean of the next readings recorded every 15 minutes during daytime working… Continue reading Long #Working Hours and the Prevalence of Masked and Sustained #Hypertension

Associations of Processed #Meat, Unprocessed Red Meat, Poultry, or #Fish Intake With Incident #Cardiovascular Disease and All-Cause Mortality

Although the associations between processed meat intake and cardiovascular disease (CVD) and all-cause mortality have been established, the associations of unprocessed red meat, poultry, or fish consumption with CVD and all-cause mortality are still uncertain.. .. Intake of processed meat (adjusted HR, 1.03 [95% CI, 1.02-1.05]; adjusted ARD, 0.90% [95% CI, 0.43%-1.38%]) or unprocessed red… Continue reading Associations of Processed #Meat, Unprocessed Red Meat, Poultry, or #Fish Intake With Incident #Cardiovascular Disease and All-Cause Mortality

Updating insights into #rosiglitazone and cardiovascular risk through shared data: individual patient and summary level meta-analyses

individual patient level data (IPD) ..The odds ratios for myocardial infarction, heart failure, cardiovascular related death, and non-cardiovascular related death were 1.17 (0.92 to 1.51), 1.54 (1.14 to 2.09), 1.15 (0.55 to 2.41), and 1.18 (0.60 to 2.30), respectively. For analyses including trials for which IPD were not available, odds ratios for myocardial infarction and… Continue reading Updating insights into #rosiglitazone and cardiovascular risk through shared data: individual patient and summary level meta-analyses

Updating insights into #rosiglitazone and #cardiovascular risk through shared data: individual patient and summary level meta-analyses

..The odds ratios for myocardial infarction, heart failure, cardiovascular related death, and non-cardiovascular related death were 1.17 (0.92 to 1.51), 1.54 (1.14 to 2.09), 1.15 (0.55 to 2.41), and 1.18 (0.60 to 2.30), respectively. For analyses including trials for which IPD were not available, odds ratios for myocardial infarction and cardiovascular related death were attenuated… Continue reading Updating insights into #rosiglitazone and #cardiovascular risk through shared data: individual patient and summary level meta-analyses

#Lifestyle Changes in Relation to Initiation of #Antihypertensive and #Lipid‐Lowering Medication: A Cohort Study

Lifestyle modification is a key component of cardiovascular disease prevention before and concurrently with pharmacologic interventions.. ..In participants who initiated medication use, body mass index increased more (difference in change 0.19; 95% CI, 0.16–0.22) and physical activity declined (−0.09 metabolic equivalent of task hour/day; 95% CI, −0.16 to −0.02) compared with noninitiators. The likelihood of… Continue reading #Lifestyle Changes in Relation to Initiation of #Antihypertensive and #Lipid‐Lowering Medication: A Cohort Study

Early onset of #menopause is associated with increased peripheral #atherosclerotic plaque volume and progression

Cardiovascular disease (CVD) is the leading cause of death in western countries. One risk factor unique to women is the menopausal status. The aim of this study was to analyse the influence of the onset of menopause (MP) on the extent and progression of atherosclerotic plaque volume (PV). ..110 consecutive postmenopausal women (mean age 65.5)… Continue reading Early onset of #menopause is associated with increased peripheral #atherosclerotic plaque volume and progression

#Pet Ownership and #Cardiovascular Health in the US general population

The 2013 American Heart Association Scientific Statement on pet ownership and cardiovascular risk suggested that dog ownership is probably associated with decreased cardiovascular risk. Several studies have been shown that pet ownership, particularly of dogs, is associated with increased physical activity levels, social support, and improved outcomes after a major cardiovascular event.. Pet owners were… Continue reading #Pet Ownership and #Cardiovascular Health in the US general population

#Marijuana Use in Patients With #Cardiovascular Disease: JACC Review Topic of the Week

Marijuana use is increasing as more states are legalizing cannabis for both medicinal and recreational purposes. National survey data estimate that >2 million Americans with established cardiovascular diseases currently use or have used marijuana in its variety of forms, including inhalation and vaping. Cannabinoid receptors are distributed in multiple tissue beds and cells, including platelets,… Continue reading #Marijuana Use in Patients With #Cardiovascular Disease: JACC Review Topic of the Week

High-#protein diets increase #cardiovascular risk by activating macrophage mTOR to suppress mitophagy

High-protein diets are commonly utilized for weight loss, yet they have been reported to raise cardiovascular risk. The mechanisms underlying this risk are unknown. Here, we show that dietary protein drives atherosclerosis and lesion complexity. Protein ingestion acutely elevates amino acid levels in blood and atherosclerotic plaques, stimulating macrophage mammalian target of rapamycin (mTOR) signalling.… Continue reading High-#protein diets increase #cardiovascular risk by activating macrophage mTOR to suppress mitophagy