BackgroundThe pattern of structural brain abnormalities in anorexia nervosa (AN) is still not well understood. While several studies report substantial deficits in grey matter volume and cortical thickness in acutely underweight patients, others find no differences, or even increases in patients compared with healthy controls. Recent weight regain before scanning may explain some of this… Continue reading Brain Structure in Acutely Underweight and Partially Weight-Restored Individuals with Anorexia Nervosa – A Coordinated Analysis by the ENIGMA Eating Disorders Working Group
Tag: Brain
A retrospective observational study on cases of anaplastic brain tumors treated with the Di Bella Method: A rationale and effectiveness
AbstractDespite all the new developments in cancer therapy, the life expectancy of patients with malignant anaplastic brain tumors and glioblastoma multiform (GBM) remains short. Since the establishment of the Di Bella Method (DBM) in cancer therapy, DBM was able to increase the survival rate and life quality, without overt toxicity, in comparison to what is… Continue reading A retrospective observational study on cases of anaplastic brain tumors treated with the Di Bella Method: A rationale and effectiveness
Big-C creativity in artists and scientists is associated with more random global but less random local fMRI functional connectivity.
Brain mechanisms underlying creativity are largely unknown and few studies have involved exceptionally creative individuals. We examined functional MRI (fMRI) connectivity in a “smart comparison group” (SCG; n = 24), and in exceptionally creative (“Big C”) visual artists (VIS; n = 21) and scientists (SCI; n = 21). Groups were matched on age, sex, and… Continue reading Big-C creativity in artists and scientists is associated with more random global but less random local fMRI functional connectivity.
Decoding COVID-19 mRNA Vaccine Immunometabolism in Central Nervous System: human brain normal glial and glioma cells by Raman imaging
The paper presents the effect of COVID-19 mRNA (Pfizer/BioNT) vaccine on in vitro glial cells of the brain studied by means of Raman spectroscopy and imaging.. The results obtained for human brain normal and tumor glial cells of astrocytes, astrocytoma, glioblastoma incubated with the Covid-19 mRNA vaccine Pfizer/BioNT vaccine show alterations in the reduction-oxidation pathways… Continue reading Decoding COVID-19 mRNA Vaccine Immunometabolism in Central Nervous System: human brain normal glial and glioma cells by Raman imaging
Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study
BackgroundA new syndrome of vaccine-induced immune thrombotic thrombocytopenia (VITT) has emerged as a rare side-effect of vaccination against COVID-19. Cerebral venous thrombosis is the most common manifestation of this syndrome but, to our knowledge, has not previously been described in detail. We aimed to document the features of post-vaccination cerebral venous thrombosis with and without… Continue reading Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study
Saccade-related neural communication in the human medial temporal lobe is modulated by the social relevance of stimuli
Humans predominantly explore their environment by moving their eyes. To optimally communicate and process visual information, neural activity needs to be coordinated with the execution of eye movements. We investigated the coordination between visual exploration and interareal neural communication by analyzing local field potentials and single neuron activity in patients with epilepsy. We demonstrated that… Continue reading Saccade-related neural communication in the human medial temporal lobe is modulated by the social relevance of stimuli
Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism
The mediobasal hypothalamus (MBH) is the central region in the physiological response to metabolic stress. The FK506-binding protein 51 (FKBP51) is a major modulator of the stress response and has recently emerged as a scaffolder regulating metabolic and autophagy pathways. However, the detailed protein-protein interactions linking FKBP51 to autophagy upon metabolic challenges remain elusive. We… Continue reading Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism
Associations between alcohol consumption and gray and white matter volumes in the UK Biobank
Heavy alcohol consumption has been associated with brain atrophy, neuronal loss, and poorer white matter fiber integrity. However, there is conflicting evidence on whether light-to-moderate alcohol consumption shows similar negative associations with brain structure. To address this, we examine the associations between alcohol intake and brain structure using multimodal imaging data from 36,678 generally healthy… Continue reading Associations between alcohol consumption and gray and white matter volumes in the UK Biobank
Sensory-Tactile Functional Mapping and Use-Associated Structural Variation of the Human Female Genital Representation Field
The precise location of the human female genital representation field in the primary somatosensory cortex (S1) is controversial and its capacity for use-associated structural variation as a function of sexual behavior remains unknown. We used an fMRI-compatible sensory-tactile stimulation paradigm to functionally map the location of the female genital representation field in 20 adult women.… Continue reading Sensory-Tactile Functional Mapping and Use-Associated Structural Variation of the Human Female Genital Representation Field
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