To address a crucial knowledge deficiency concerning the correlation between fried food consumption and the risk of anxiety and depression, here we revealed that frequent fried food consumption is strongly associated with a higher risk of anxiety and depression. Notably, acrylamide is a representative contaminant in fried foods, thereby further elucidating its toxicological mode of… Continue reading High fried food consumption impacts anxiety and depression due to lipid metabolism disturbance and neuroinflammation
Category: Psychiatry
Music to improve sleep quality in adults with depression-related insomnia (MUSTAFI): randomized controlled trial
Background Insomnia in depression is common and difficult to resolve. Unresolved depression-related sleep disturbances increase risk of relapse at high costs for individuals and society. Trials have suggested music for insomnia in various populations, but there is little research on the effectiveness of music for depression-related insomnia. Methods We examined the efficacy of a music… Continue reading Music to improve sleep quality in adults with depression-related insomnia (MUSTAFI): randomized controlled trial
Burnout, Professionalism, and the Quality of US Health Care
Physician burnout is a major threat to health care quality, patient outcomes, and the vitality of the medical workforce.1 More than half of US physicians report at least 1 symptom of burnout—nearly twice the rate of the general working population—and many also experience depression, anxiety, or suicidal ideation.2 Burnout is estimated to cost the health… Continue reading Burnout, Professionalism, and the Quality of US Health Care
Depressive Symptoms and Risk of Acute Stroke: INTERSTROKE Case-Control Study
Depression has been reported to be a risk factor for acute stroke, based largely on studies in high-income countries. In the INTERSTROKE study, we explored the contribution of depressive symptoms to acute stroke risk and 1-month outcome across regions of the world, within subpopulations and by stroke typeMethodsINTERSTROKE is an international case-control study of risk… Continue reading Depressive Symptoms and Risk of Acute Stroke: INTERSTROKE Case-Control Study
Effectiveness of physical activity interventions for improving depression, anxiety and distress: an overview of systematic reviews
Objective To synthesise the evidence on the effects of physical activity on symptoms of depression, anxiety and psychological distress in adult populations.Design Umbrella review.Data sources Twelve electronic databases were searched for eligible studies published from inception to 1 January 2022.Eligibility criteria for selecting studies Systematic reviews with meta-analyses of randomised controlled trials designed to increase… Continue reading Effectiveness of physical activity interventions for improving depression, anxiety and distress: an overview of systematic reviews
Effect of Technology-Enhanced Screening in Addition to Standard Targeted Clinician Education on the Duration of Untreated PsychosisA Cluster Randomized Clinical Trial
Reducing the duration of untreated psychosis (DUP) is essential to improving outcomes for people with first-episode psychosis (FEP). Current US approaches are insufficient to reduce DUP to international standards of less than 90 days.Objective To determine whether population-based electronic screening in addition to standard targeted clinician education increases early detection of psychosis and decreases DUP,… Continue reading Effect of Technology-Enhanced Screening in Addition to Standard Targeted Clinician Education on the Duration of Untreated PsychosisA Cluster Randomized Clinical Trial
Gut microbiome-wide association study of depressive symptoms
Depression is one of the most poorly understood diseases due to its elusive pathogenesis. There is an urgency to identify molecular and biological mechanisms underlying depression and the gut microbiome is a novel area of interest. Here we investigate the relation of fecal microbiome diversity and composition with depressive symptoms in 1,054 participants from the… Continue reading Gut microbiome-wide association study of depressive symptoms
Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder: A Living Clinical Guideline From the American College of Physicians
...Recommendation 1a:ACP recommends monotherapy with either cognitive behavioral therapy or a second-generation antidepressant as initial treatment in patients in the acute phase of moderate to severe major depressive disorder (strong recommendation; moderate-certainty evidence).Recommendation 1b:ACP suggests combination therapy with cognitive behavioral therapy and a second-generation antidepressant as initial treatment in patients in the acute phase of… Continue reading Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder: A Living Clinical Guideline From the American College of Physicians
Social isolation and 9-year dementia risk in community-dwelling Medicare beneficiaries in the United States
BackgroundSocial isolation can influence whether older adults develop dementia. We examine the association between social isolation and incident dementia among older adults in a nationally representative sample of community dwelling older adults in the United States (U.S.). We also investigate whether this association varies by race and ethnicity.MethodsData (N = 5022) come from the National Health and… Continue reading Social isolation and 9-year dementia risk in community-dwelling Medicare beneficiaries in the United States
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