Question Is clinical use of artificial intelligence (AI)–generated draft radiograph reports associated with documentation efficiency, clinical accuracy, textual quality, and ability to promptly detect pneumothorax requiring intervention?Findings In this cohort study, in 11 980 model-assisted radiograph interpretations in live clinical care, model use was associated with a 15.5% documentation efficiency improvement, with no change in radiologist-evaluated… Continue reading Efficiency and Quality of Generative #AI–Assisted #Radiograph Reporting
Category: practice
Does #oral #hygiene prevents nosocomial #infections in hospitalized patients? A systematic review and meta-analysis
Background: This study aimed to evaluate the impact of oral hygiene (OH) with chlorhexidine (CHX) on the evolution of nosocomial infections (NI).Material and methods: Electronic searches were carried out in PubMed, Scopus, Cochrane Library, Web of Science, VHL, and Grey Literature databases. Randomized clinical trials were included. Methodological quality and risk of bias were assessed… Continue reading Does #oral #hygiene prevents nosocomial #infections in hospitalized patients? A systematic review and meta-analysis
#Artificial #intelligence vs human #clinicians: a comparative analysis of complex medical query handling across the USA and Australia
PurposeThis study sought to explore the practical application and effectiveness of AI-generated responses in healthcare and compared these with human clinician responses to complex medical queries in the USA and Australia. The study identifies strengths and limitations of AI in clinical settings and offers insights into its potential to enhance healthcare delivery.Design/methodology/approachA comparative analysis used… Continue reading #Artificial #intelligence vs human #clinicians: a comparative analysis of complex medical query handling across the USA and Australia
Evaluation of an Ambient Artificial Intelligence Documentation Platform for #Clinicians
Importance The increase of electronic health record (EHR) work negatively impacts clinician well-being. One potential solution is incorporating an ambient artificial intelligence (AI) documentation platform.Objective To understand clinician experience before and after implementing ambient AI.Design, Setting, and Participants This quality improvement study was a pilot evaluation with before and after survey and EHR metrics conducted… Continue reading Evaluation of an Ambient Artificial Intelligence Documentation Platform for #Clinicians
Sociodemographic #biases in medical decision making by large language models
Large language models (LLMs) show promise in healthcare, but concerns remain that they may produce medically unjustified clinical care recommendations reflecting the influence of patients’ sociodemographic characteristics. We evaluated nine LLMs, analyzing over 1.7 million model-generated outputs from 1,000 emergency department cases (500 real and 500 synthetic). Each case was presented in 32 variations (31… Continue reading Sociodemographic #biases in medical decision making by large language models
Share onGlobal Effect of #Cardiovascular Risk Factors on Lifetime Estimates
Five risk factors account for approximately 50% of the global burden of cardiovascular disease. How the presence or absence of classic risk factors affects lifetime estimates of cardiovascular disease and death from any cause remains unclear.MethodsWe harmonized individual-level data from 2,078,948 participants across 133 cohorts, 39 countries, and 6 continents. Lifetime risk of cardiovascular disease… Continue reading Share onGlobal Effect of #Cardiovascular Risk Factors on Lifetime Estimates
‘Experimentum Crucis’: Hauksbee the Younger’s ‘decisive experiment’ for comparing the ‘Safety and Efficacy’ of new medicines (1743)
AbstractIn 1743 Francis Hauksbee the Younger published a proposal for an ‘Experimentum Crucis’ (‘decisive experiment’) to compare his own medication for venereal disease with other treatments. Previously he had sought to replicate the methods of James Jurin FRS, who published outcomes from inoculation against smallpox in the 1720s. By seeking to record outcomes (‘Safety and… Continue reading ‘Experimentum Crucis’: Hauksbee the Younger’s ‘decisive experiment’ for comparing the ‘Safety and Efficacy’ of new medicines (1743)
Defining ortholog-specific UHRF1 inhibition by STELLA for #cancer therapy
UHRF1 maintains DNA methylation by recruiting DNA methyltransferases to chromatin. In mouse, these dynamics are potently antagonized by a natural UHRF1 inhibitory protein STELLA, while the comparable effects of its human ortholog are insufficiently characterized, especially in cancer cells. Herein, we demonstrate that human STELLA (hSTELLA) is inadequate, while mouse STELLA (mSTELLA) is fully proficient… Continue reading Defining ortholog-specific UHRF1 inhibition by STELLA for #cancer therapy
The massed-spaced #learning effect in non-neural human #cells
The massed-spaced effect is a hallmark feature of memory formation. We now demonstrate this effect in two separate non-neural, immortalized cell lines stably expressing a short-lived luciferase reporter controlled by a CREB-dependent promoter. We emulate training using repeated pulses of forskolin and/or phorbol ester, and, as a proxy for memory, measure luciferase expression at various… Continue reading The massed-spaced #learning effect in non-neural human #cells
2 Medical News 