Music can effectively induce emotional arousal, which is associated with the release of stress hormones that are important for the emotional modulation of memory. Thus, music may serve as a powerful modulator of memory and mood, making it a promising therapeutic tool for memory and mood disorders such as Alzheimer's disease or depression. However, music's… Continue reading Fine-Tuning the Details: Post-encoding #Music Differentially Impacts General and Detailed #Memory
Category: Neurology
Decoding #memory function through naturalistic gaze patterns
#Eye movements are closely linked to encoding and retrieval processes, with changes in viewing behavior reflecting age- and pathology-related memory decline. In the current study, we leveraged this relationship to explore possible gaze-based indicators of memory function. Across two task-free viewing experiments, we investigated changes in naturalistic viewing behavior across five participant groups spanning a… Continue reading Decoding #memory function through naturalistic gaze patterns
Human #thalamocortical structural connectivity develops in line with a hierarchical axis of #cortical plasticity
Human cortical development follows a hierarchical, sensorimotor-to-association sequence. The brain’s capacity to enact this sequence indicates that it relies on unknown mechanisms to regulate regional differences in the timing of cortical maturation. Given evidence from animal systems that thalamic axons mechanistically regulate periods of cortical plasticity, here we evaluate in humans whether the development of… Continue reading Human #thalamocortical structural connectivity develops in line with a hierarchical axis of #cortical plasticity
#Electrophysiological correlates of dynamic #cycling in #Parkinson’s diseaseAuthor
Physical exercise like dynamic cycling has shown promise in enhancing motor function in Parkinson’s disease (PD). We examined the underlying mechanisms of dynamic cycling in PD, emphasizing its impact on the activity of the subthalamic nucleus (STN), a pivotal region within the basal ganglia.MethodsThe investigation involved 100 dynamic cycling sessions conducted among nine PD individuals.… Continue reading #Electrophysiological correlates of dynamic #cycling in #Parkinson’s diseaseAuthor
Phenome-wide Analysis of #Diseases in Relation to Objectively Measured #Sleep Traits and Comparison with Subjective Sleep Traits in 88,461 Adults
Background: Sleep traits have been suggested to correlate with various diseases, but most evidence is based on subjective sleep measurement. We investigated the associations of accelerometer-derived objective sleep traits with diseases throughout physiological systems to ascertain whether the disease spectrum related to objective sleep traits differs from that related to subjective sleep traits. Methods: In… Continue reading Phenome-wide Analysis of #Diseases in Relation to Objectively Measured #Sleep Traits and Comparison with Subjective Sleep Traits in 88,461 Adults
Time to Diagnosis in #Dementia: A Systematic Review With Meta-Analysis
Timely dementia diagnosis is a global priority, reflected in most national and regional policies and plans. Nevertheless, there are currently no robust estimates of the average time to diagnosis (TTD) and factors influencing diagnostic intervals. This article presents the first systematic review of quantitative studies on TTD in dementia and the factors associated with its… Continue reading Time to Diagnosis in #Dementia: A Systematic Review With Meta-Analysis
Association Between #COVID-19 #Vaccination and #Neuropsychiatric Conditions
Introduction: This study explores the potential associations between COVID-19 vaccination and neuropsychiatric conditions. Methods: Data were collected from the CDC and FDA. The VAERS database was queried from January 1, 1990, to December 27, 2024, for adverse events (AEs) involving neuropsychiatric complications following COVID-19 vaccination. The timeframe included 420 months for all vaccines except COVID-19… Continue reading Association Between #COVID-19 #Vaccination and #Neuropsychiatric Conditions
Classification of #Parkinson’s disease and isolated #REM sleep behaviour disorder: delineating progression markers from the sebum volatilome
Parkinson’s Disease (PD) has been associated with a distinct odour, emanating from the skin and strongest in sebum-rich areas. Here, volatile components from sebum were analysed directly with Thermal Desorption Gas Chromatography - Mass Spectrometry. We analysed samples from subjects with clinically established PD (n = 46), controls (n = 28) and participants with isolated REM sleep behaviour disorder… Continue reading Classification of #Parkinson’s disease and isolated #REM sleep behaviour disorder: delineating progression markers from the sebum volatilome
Effects of various #exercise interventions in #insomnia patients: a systematic review and network meta-analysis
Objectives To compare the effectiveness of different exercise interventions in improving sleep quality and alleviating insomnia severity among patients with insomnia.Design Our study design was a systematic review and network meta-analysis.Eligibility criteria Our study eligibility criteria was restricted to include randomised controlled trials (RCTs) involving adults with insomnia that evaluated exercise-based interventions.Data sources PubMed, Cochrane… Continue reading Effects of various #exercise interventions in #insomnia patients: a systematic review and network meta-analysis